Protein kinase C (PKC) is a family of serine/threonine protein kinases that plays a central role in transducing extracellular signals into a variety of intracellular responses ranging from cell proliferation to apoptosis. Nine PKC genes have been identified in the human genome, which encode 10 proteins. Each member of this protein kinase family displays distinct biochemical characteristics and is

This well-written paper is devoted to proving pointwise gradient estimates for functions satisfying a suitable inequality, which arises, for instance, in parabolic obstacle problems as well as in the study of parabolic $Q$-minima.

The local density theory is developed by Hohenberg, Kohn and Sham is extended to the spin polarized case. A spin dependent one- electron potential pertinent to ground state properties is obtained from calculations of the total energy per electron made with a `bubble' (or random phase) type of dielectric function. The potential is found to be well represented by an analytic expression corresponding

Different system identification methods have been applied to determine ship steering dynamics from full-scale experiments. The techniques used include output error, maximum likelihood and more general prediction error methods. Different model structures have been investigated ranging from input-output models in difference equation form to the equations of motion in their natural form. Effects of d

A 5.4GHz multiple-pass ring voltage controlled oscillator (VCO) based phase-locked loop (PLL) is described. For the sake of active devices’ sensitivity to process and temperature regarding ring oscillators, an effective automatic frequency calibration scheme is proposed. A new process-independent differential to single (DTOS) is used to adjust control voltage range and loop gain. The chip is imple

This key note paper discusses heterosexuality, heteronormativity and exclusion by homophobia.

Results are presented of proton-induced x-ray emission analysis of aerosol samples taken in Miami, Fla., in the summer of 1974. Elemental concentrations and elemental ratios as a function of particle size are shown for 13 elements. These size distributions allow the determination of the sources of several elements observed in the Miami aerosol. Data from north Florida and Bermuda are compared.

Due to increasing demand for software project managers in industry, efforts are needed to develop the management-related knowledge and skills of the current and future software workforce. In particular, university education needs to provide to their computer science students not only technology-related skills but, in addition, a basic understanding of typical phenomena occurring in industrial (and