Small leucine-rich proteoglycans play important roles in the organization of the extracellular matrix as well as for the regulation of cell behavior; two biological processes that are essential for angiogenesis. We investigated consequences of the targeted ablation of decorin (DCN), biglycan (BGN) and fibromodulin (FMOD) genes on inflammation-induced angiogenesis in the cornea. In wildtype mice, D

Absence or reduced activity of coagulation factor IX (FIX) causes the severe bleeding disorder haemophilia B. FIX contains a Gla module, two epidermal growth factor-like (EGF) modules, and a serine protease region. I characterized a monoclonal antibody and found that it recognizes an epitope around residues 72 and 80 in the C-terminal part of EGF1 in human FIX. The antibody exhibited 10-fold great

New basis sets of the atomic natural orbital (ANO) type have been developed for the atoms Li-Fr and Be-Ra. The ANOs have been obtained from the average density matrix of the ground states and the lowest excited states of the atom, the positive ion, and the dimer at its equilibirium geometry. Scalar realtivisitc effects are included through the use of a Douglas-Kroll Hamiltonian. Multiconfiguration

We studied narrow (submicron) constrictions in the layers of ferromagnetic semiconductor (Ga, Mn)As. We have demonstrated a contribution of the quantum localization effects to the magnetoresistance of the constricted samples. We have also found a negative contribution of a domain wall trapped in the constriction to the resistance, due presumably to the erasing of the localization effects by the do

The aim of the study was to test the hypothesis that a newborn infant's cry can be used in conjunction with an instrument to measure pain. Crying due to pain was analysed after a heel-prick stimulus. In a prospective, descriptive study, 50 healthy newborn infants were subjected to a heel-prick for phenylketonuria screening. Their cries of pain were recorded and analysed. Duration of the crying sou

Relations between locus of control, coping strategies and emotional well-being in persons with traumatically acquired spinal cord lesion (SCL) were examined. The sample included 132 community-residing adults. Structural equation modelling, including confirmatory factor analysis, was used. A model was hypothesized based on the transactional theory of stress and coping where coping strategies mediat

Popular Abstract in Swedish Vattenkraft är Islands främsta energikälla. År 2005 svarade vattenkraft för 80,8% av all elproduktion på Island (7015 Gwh). Vattenkraft påverkas av både variationer och förändringar i vattenflöden. Denna avhandling fokuserar på studier av trender och variationer i tidsserier av vattenflöden och klimatvariabler, kombinerat med modellering av avrinningsområden och analys Hydropower is the main source of electricity production in Iceland. In 2005, 80.8% of all electricity was generated by hydropower (7015 GWh). Hydropower production is affected both by variations and changes in discharge. This thesis focuses on studies of the trends and the variability found in records of discharge and climatic variables, combined with watershed modelling and an analysis of a proje

The mixotroph Poterioochromonas malhamensis was grown in batch and semicontinuous cultures in order to examine the dependence of phagotrophy versus phototrophy at bacterial densities similar to those found in oligo- and mesotrophic lakes in combination with differing light regimes. In addition, the growth rates and biomass accumulation of the mixotroph were compared to those of the heterotroph Spu

Essä om bilden av andra världskriget under 1990-talet

We present new results for relative sea-level change for Southern Greenland for the interval from 9000 cal. yr BP to the present. Together with earlier work from the same region this yields a nearly complete record from the time of deglaciation to the present. Isolation and/or transgression sequences in one lake and five tidal basins have been identified using lithostratigraphic analyses, sediment

High-spin states of the neutron deficient (100)pd nucleus have been investigated via the Cr-50(Ni-58, 4p alpha) and Zn-70(S-36,6n) heavy-ion induced reactions. For the detection of evaporated particles and gamma rays the NORDBALL array equipped with ancillary detectors and the EUROGAM II detector system were utilized. By the use of in-beam spectroscopic methods 89 transitions belonging to (100)pd

The effects of intracameral injections of cholecystokinin (CCK) on the pupil size were determined in monkeys, cats, rabbits, rats and guinea-pigs. In animals under muscarinic cholinergic blockade, CCK caused miosis in monkeys but not in the other species investigated. In monkeys CCK-8 was more potent than CCK-33, which was, however, much more potent than non-sulphated CCK-8. These observations ind

Abstract in Norwegian Den kalde krigens slutt og Sovjetunionens fall har gjort det lettere for personlige kontakter på tvers av de «gamle grenser». Økt migrasjon fra det tidligere Sovjet, samt fra de nye statene i Sentral- og Øst-Europa, er et kjennetegn på den postsosialistiske perioden. Denne statistisk målbare forandringen har også fått følger på det diskursive planet. Migrasjonsproblematikken

Purpose: To investigate the effect of different levels of visual field defect in glaucoma on utilities and to test if utilities could be assessed using a general questionnaire such as the EQ-5D. Methods: A cross-sectional study in 199 patients with ocular hypertension or open-angle glaucoma grouped into 5 severity stages according to visual field defects was performed in 4 specialized ophthalmic c

While the concept of regular equivalence is equally applicable to dichotomous as well as valued networks, the identification of regular blocks in regular blockmodels is somewhat problematic when dealing with valued networks. Applying the standard procedure for identifying ties in such blockmodels, a procedure perhaps most suited for dichotomous networks, does tend to generate block images and redu

CS 22949-037 is one of the most metal-poor giants known ([Fe/H]~-4.0),and it exhibits large overabundances of carbon and nitrogen (Norris etal.). Using VLT-UVES spectra of unprecedented quality, regardingresolution and S/N ratio, covering a wide wavelength range (from lambda= 350 to 900 nm), we have determined abundances for 21 elements in thisstar over a wide range of atomic mass. The major new d

This study is about how the 'global' becomes localized and how the 'local' is articulated through the 'global'. It deals with the Van (forest) Gujjars, a people of nomadic forest pastoralists who inhabit the Central Himalayas of India. The study has two main foci: One is the everyday life-world of the Van Gujjars in the forest - a Van Gujjar ethnography - and the other is the conflict over 'conser

PURPOSE: This study used simultaneous videomanometry to measure pressure characteristics in a group of patients with evidence of laryngeal and/or tracheal barium penetration, and to compare the results to those of one group of healthy volunteers and one group of patients with dysphagia but a normal barium swallow. MATERIAL AND METHODS: Videomanometry during barium swallowing was performed in 25 pa