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Impact of non-orthogonal training on performance of downlink base station cooperative transmission

Base station (BS) cooperative transmission is a promising technique to improve spectral efficiency of cellular systems, using which the channels become asymmetric in average gain. In this paper, we study the impact of the asymmetric channel gains on the performance of coherent cooperative transmission systems, when minimum mean square error (MMSE) and least square (LS) channel estimators are appli

Leukotriene receptors are differently expressed in fibroblast from peripheral versus central airways in asthmatics and healthy controls.

Leukotrienes are involved in airway inflammation, and are believed to stimulate airway remodeling in asthma. The aim of the project was to investigate the expression of leukotriene receptors in peripheral and central airway fibroblasts. Peripheral and central airway fibroblasts, from asthmatics and healthy controls, were investigated for the amount of cysteinyl-leukotriene receptors (CysLT(1) and

The time aspect of bioenergy - Climate impacts of solid biofuels due to biogenic carbon dynamics

The climate impacts from bioenergy involve an important time aspect. Using forest residues for energy may result in high initial emissions, but net emissions are reduced over time since, if the residues were left on the ground, they would decompose and release CO2 to the atmosphere. This article investigates the climate impacts from bioenergy with special focus on the time aspects. More specifical

When does a crack grow under mode II conditions?

Even cracks which seem to be favourably oriented for mode II growth might extend in mode I by kinking. The conditions that favour mode I or mode II growth are examined. It is shown that a high confining pressure promotes mode II growth and so does a low ratio between the critical stress intensity factors of modes II and I. Quantitative results are given for different coefficients of friction and c

Genetic Dissection Reveals Diabetes Loci Proximal to the Gimap5 Lymphopenia Gene.

Congenic DRF.(f/f) rats are protected from type 1 diabetes (T1D) by 34 Mb of F344 DNA introgressed proximal to the Gimap5 lymphopenia gene. To dissect the genetic factor(s) that confer protection from T1D in the DRF.(f/f) rat line, DRF.(f/f) rats were crossed to inbred BBDR or DR.(lyp/lyp) rats to generate congenic sublines that were genotyped, monitored for T1D and positional candidate genes sequ

Increased mitogenicity of an alphabeta heterodimeric PDGF receptor complex correlates with lack of RasGAP binding

The different platelet-derived growth factor (PDGF) isoforms cause activation of their alpha and beta protein tyrosine kinase receptors through dimerization. Homodimerization as well as heterodimerization of receptors occur. It has been shown previously that the heterodimeric receptor complex mediates a stronger mitogenic response than either of the homodimeric complexes. In this report, we show t

Defective insulin secretion by chronic glucagon receptor activation in glucose intolerant mice.

Stimulation of insulin secretion by short-term glucagon receptor (GCGR) activation is well characterized, however, the effect of long-term GCGR activation on beta-cell function is not known, but of interest, since hyperglucagonemia occurs early during development of type 2 diabetes. Therefore, we examined whether chronic GCGR activation affects insulin secretion in glucose intolerant mice. To indu

Enrollment experiences in a pediatric longitudinal observational study: The Environmental Determinants of Diabetes in the Young (TEDDY) study.

OBJECTIVE: Our objective was to identify characteristics of infants and their families who were enrolled, refused to enroll, or were excluded from The Environmental Determinants of Diabetes in the Young (TEDDY) study. METHOD: 16,435 infants screened at birth and identified as at increased genetic risk for type 1 diabetes (T1DM) were placed into one of three categories: enrolled, excluded, or refus

Scandinavian rational choice sociology

The present status of rational choice sociology in Scandinavia is discussed in the form of a review, examining representative work and highlighting important scholars. Despite a reputation of having a strong Scandinavian rational choice tradition, rational choice sociology is practically non-existent in Denmark, Finland and Iceland. Rational choice sociology in Scandinavia is by-and-large concentr

The current distribution on a circular disc

In this paper we derive the surface-current distribution on a perfectly conducting circular disc. The current is obtained by calculating the limit of the surface currents on an oblate spheroid as the thickness goes to zero. The null-field approach is used. We show that it is possible to calculate all quantities in terms of the spherical basis functions, thus avoiding the cumbersome spheroidal basi

Quantitative interpretation of gold nanoparticle-based bioassays designed for detection of immunocomplex formation

The authors present in this paper how the extended Mie theory can be used to translate not only end-point data but also temporal variations of extinction peak-position changes, peak(t), into absolute mass uptake, (t), upon biomacromolecule binding to localized surface plasmon resonance (SPR) active nanoparticles (NPs). The theoretical analysis is applied on a novel sensor template composed of a th

The t(X;7)(q22;q34) in paediatric T-cell acute lymphoblastic leukaemia results in overexpression of the insulin receptor substrate 4 gene through illegitimate recombination with the T-cell receptor beta locus.

Summary The t(X;7)(q22;q34), a translocation not previously reported in a neoplastic disorder, was identified and molecularly characterised in a paediatric T-cell acute lymphoblastic leukaemia (T-ALL), subsequently shown also to harbour a deletion of 6q, a STIL/TAL1 fusion and an activating NOTCH1 mutation. The t(X;7) was further investigated using fluorescence in situ hybridisation (FISH), real-t

Repeated electroconvulsive seizures increase the number of vessel-associated macrophages in rat hippocampus.

OBJECTIVES: We have previously reported that electroconvulsive seizure (ECS)-an animal model of the antidepressant treatment electroconvulsive therapy-causes glial cell activation in hippocampus and other limbic areas. In the current study, we have investigated whether the cellular response to ECS includes recruitment and infiltration of nonresident macrophages into the hippocampal brain parenchym

The cognitive profile and CSF biomarkers in dementia with Lewy bodies and Parkinson's disease dementia.

Dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) may be viewed as different points on a continuum reflecting the regional burden and distribution of pathology. An important clinical consideration is overlapping Alzheimer's disease (AD) pathology, since it has been reported that associated AD pathology in DLB shortens survival and leads to a more rapid cognitive decline. We ai

Anthropometric factors and ovarian cancer risk in the Malmö Diet and Cancer Study.

Objective: To examine the associations of measured anthropometric factors, including general and central adiposity, with epithelial ovarian cancer (EOC) risk in the Malmö Diet and Cancer Study. Methods: In 93 incident EOC cases from a Swedish population-based prospective cohort study, seven anthropometric factors; height, weight, BMI, body fat percentage, waist- and hip circumference, and waist-hi