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L-DOPA-induced dyskinesia (LID) is a significant complication of dopamine replacement therapy in Parkinson's disease (PD), and the specific role of different dopamine receptors in this disorder is poorly understood. We set out to compare patterns of dyskinetic behaviours induced by the systemic administration of L-DOPA and D1 or D2 receptor (D1R, D2R) agonists in mice with unilateral 6-hydroxydopa

Academics are becoming accustomed to growing demands on ‘performance’ as universities place increasing emphasis on quantifiable research outputs. Despite the rapid ascendancy of bibliometrics, limited empirical research has considered the definitions of “research performance” employed by institutions, and subsequent academic responses. Drawing on exploratory data collected from 58 university-based

The systematic position of a large and strikingly coloured reddish-black moth, Cartaletis dargei Herbulot, 2003 (Geometridae: Sterrhinae) from Tanzania, has remained questionable since its description. Here we present molecular and morphological evidence showing that Cartaletis dargei only superficially resembles true Cartaletis Warren, 1894 (the relative name currently considered a junior synonym

A study on the freshwater dinoflagellate (Dinophyceae) of Colombia was carried out based on samples from four swamps, nine reservoirs, a small insular lake, and additional specimens deposited in the phycological collection of Universidad de Antioquia, Colombia, and the collection of Universidad de La Plata, Argentina. For most species, detailed morphological descriptions and illustrations are prov

Diversifications often proceed along highly conserved, evolutionary trajectories. These patterns of covariation arise in ontogeny, which raises the possibility that adaptive morphologies are biased towards trait covariations that resemble growth trajectories. Here, we test this prediction in the diverse clade of Anolis lizards by investigating the covariation of embryonic growth of 13 fore- and hi

PURPOSE: To investigate the impact of COVID-19 in Sweden on rates of knee and hip surgeries.METHODS: We used healthcare data for the population of the southernmost region in Sweden (1.4 million inhabitants). We did an interrupted time-series analysis to estimate changes in rates and trends of joint replacements (JR), arthroscopies, and fracture surgeries for knee or hip in April-December 2020 comp

Kort sammanfattning av huvudproblemen inom utvalda områden av tysk grammatik med speciell tonvikt på formlära samt självrättande övningar till dessa.

Quinoa sourdough can safely be produced if the hygienic threshold of miss-fermentation during the start-up period is overcome. The aims of the present study are to map the microbiota of spontaneously formed quinoa sourdough without backslopping and select Lactiplantibacillus-strains. Viable count from grains and sourdough were performed and picked isolates were identified by gene sequencing. Lacti

Detecting and forecasting riverine floods is of paramount importance for adequate disaster risk management and humanitarian response. However, this is challenging in data-scarce and ungauged river basins in developing countries. Satellite remote sensing data offers a cost-effective, low-maintenance alternative to the limited in-situ data when training, parametrizing and operating flood models. UtiDetecting and forecasting riverine floods is of paramount importance for adequate disaster risk management and humanitarian response. However, this is challenging in data-scarce and ungauged river basins in developing countries. Satellite remote sensing data offers a cost-effective, low-maintenance alternative to the limited in-situ data when training, parametrizing and operating flood models. Uti

Main conclusion: Both mutant ert-c.1 and ert-d.7 carry T2-T3 translocations in the Ert-c gene. Principal coordinate analyses revealed the translocation types and translocation breakpoints. Mutant ert-d.7 is an Ert-cErt-d double mutant. Abstract: Mutations in the Ert-c and Ert-d loci are among the most common barley mutations affecting plant architecture. The mutants have various degrees of erect a

As contribution to the debate about the interpretation of the process of economic growth before the Industrial Revolution, we discuss two concerns about the currently available estimates of historical national accounts and the way in which these estimates should be interpreted. Firstly, we argue that estimates of the long-Term trends of economic growth should make use of all information contained

We present a strategy for failure resilient cloud control using model predictive control (MPC) extended with explicit recovery. Based on an arbitrary and unmodified device controller, the remotely operated MPC can safely manipulate the network controlled plant through temporary adjustment of an error signal generator. We show ways to implement the reliable cloud controller, relate it to two-degree

Mycobacterium tuberculosis remains one of the world's contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and its opportunistic coinfections. The severity of the disease coupled with drug resistance on the currently used drugs warrants for the search for alternative remedies from synthetic

There is a great need for efficient analysis of the composition of vegetable oils and fats, since it affects the physical and technical properties. However, due to the complex nature of these kind of samples, it is often difficult and costly. In the present study, we developed a Non-Aqueous Reversed-Phase HPLC method that can be used to separate and quantify different free fatty acids, fatty acid

Acute rhinosinusitis is a common infectious disease, which, in more than 90% of cases, is caused by viruses rather than by bacteria. Even so, antibiotics are often unnecessarily prescribed, and in the long run this contributes to the alarming level of antibiotics resistance. The reason is that there are no good guiding tools for defining the background reason of the infection. One main factor for