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Tissue and extracellular matrix remodelling in pulmonary fibrosis and chronic lung allograft dysfunction

In recent years, the prevalence of idiopathic pulmonary fibrosis (IPF) and post-COVID-19 pulmonary fibrosis has risen. Nevertheless, effective diagnostic and prognostic biomarkers alongside targeted treatments are lacking, making lung transplantation the last resort for many patients with end-stage disease. However, bronchiolitis obliterans syndrome (BOS), a manifestation of chronic lung allograft

The legacy of names : Persistence in social status in Sweden 1865-2015

This study explores how social origin, reflected by occupation and family name from both parents, has been passed down over the past 150 years in Sweden. It finds that intergenerational rank-rank associations in occupational status – a typical measure of social mobility – have remained surprisingly constant at levels around 0.27 – as in the US (Song et al., 2020). However, intergenerational correl

Fully Declarative Specification of Static Code Checkers

Static code checkers are tools that help software engineers by automatically finding defects without executing the programs. These tools contain a set of detectors that rely on static program analyses to find common programming defects or to enforce coding guidelines.While existing code checker frameworks package a rich collection of detectors, aimed at common bug defects, the effort to adapt thes

Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes

Type 1 diabetes is a chronic, autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. Early detection can facilitate timely intervention, potentially delaying or preventing disease onset. Circulating proteins reflect dysregulated biological processes and offer insights into early disease mechanisms. Here, we construct a genome-wide pQTL map of 1985 protein

Cult Film Atmospheres : Audiences, exhibitors, and live cinema spaces

Kultfilmsevenemang som Den Dåliga Filmfestivalen (Göteborg, 2019 och 2023-2025) och B-Filmsklubben (Malmö) erbjuder unika atmosfärer för publiken som besöker dem. I Malmö och Göteborg anordnar biograferna regelbundet festivaler och fristående visningar av kultfilmer som band andra The Room, Birdemic, och Miami Connection. Kännetecknande för dessa upplevelser är den översvallande atmosfär som skapaCult film events like The Bad Film Festival (Gothenburg, 2019 and 2023-2025) and The B-Film Club (Malmö) offer unique atmospheres to audiences. In the two Swedish cities of Malmö and Gothenburg, exhibitors run regular festivals and standalone screenings of cult films such as The Room, Birdemic, Miami Connection, and others where an effervescent atmosphere is generated, often featuring audience par

Postoperative word-finding difficulties in children with posterior fossa tumours : a crosslinguistic European cohort study

PURPOSE: Posterior fossa tumour (PFT) surgery carries a risk of mutism or severely reduced speech. As for higher-cognitive language functions, word-finding difficulties have been reported, but no study has compared pre- and postoperative word-finding speeds to identify impairment caused by surgery. The current study investigated changes in word-finding ability associated with PFT surgery and exami

Probabilistic and AI-based Methods for Moisture-safe and Sustainable Building Envelope Design

The increasing demand for energy-efficient and sustainable construction necessitates the need for building envelope designs that effectively balance moisture safety with sustainability. Improper moisture management in building envelopes can lead to severe consequences, including construction damage, decreased energy performance, and health risks associated with microbial growth. For instance, wate

Deletion of fbiC in Streptomyces venezuelae removes autofluorescence in the excitation-emission range of cyan fluorescent protein

Autofluorescence poses an impediment to fluorescence microscopy of biological samples. In the Gram-positive, soil-dwelling bacteria of the genus Streptomyces, sources of autofluorescence have not been examined systematically to date. Here, we show that the model organism for the genus, Streptomyces venezuelae, shows autofluorescence in two of the commonly used fluorescence channels for visualizing

CMS-06THE NOPHO-EUROPEAN STUDY ON CEREBELLAR MUTISM SYNDROME (CMS)

BACKGROUND: The cerebellar mutism syndrome (CMS) is one of the most disabling late effects after neurosurgery for a posterior fossa tumour in childhood. The reported incidences vary substantially in previous studies. AIMS: Pathophysiology is unknown, but damage to cerebello-thalamo-cerebral circuits is likely. The study focuses on the risk factors for development and severity of CMS including surg

Formal Analysis of Julia Key Agreement Protocol

The evolution of the fifth-generation network (5G) increases the demand and use of Internet of Things (IoT) devices extensively. The increased number of IoT devices increases the possibility of new attack surfaces, and thus even resource-constrained IoT devices need secure communication. In this work, we consider the Julia Key Agreement (JKA) protocol, which has been proposed as a secure and effic

The Colonic Vitamin D Receptor and Inflammatory Bowel Disease : No Correlation to Histologic or Endoscopic Inflammation

The role of the vitamin D receptor (VDR) in inflammatory bowel disease (IBD) is poorly described. The aim of this study was to examine the relationship between immunohistochemical VDR expression and IBD activity. The immunohistochemical expression of VDR was analysed in biopsies from active and inactive IBD in 28 patients (ulcerative colitis: 21, Crohn's disease: 7) and 12 non-IBD controls. VDR ex

Coding for intangible competitive advantage : mapping the distribution and characteristics of software-developing firms in the Swedish economy

Software is at the core of digitalisation and is often claimed to play a central role in innovation and in shaping competition across industries and firms. There are yet few studies of the extent and nature of software development across firms. We employ a unique firm-level survey comprising 3,929 firms across Sweden to analyse the distribution and characteristics of firms that invest in software

The sharing economy : definition, measurement and its relationship to capitalism

For the past decade, the sharing economy has not only grown but also expanded to cover a wide variety of different activities across the globe. Despite a lot of research, there is still no agreement on how to define and measure the sharing economy, and no consensus on whether the sharing economy is a part of or an alternative to a regular capitalist economy. This paper contributes by presenting a

Corynebacteria from the respiratory microbiota modulate inflammatory responses and associate with a reduced pneumococcal burden in the lungs

Background: Certain species from the normal respiratory tract microbiota have recently been proposed to positively influence human health. Corynebacterium propinquum and C. pseudodiphtheriticum (Corynebacteria) are two Gram-positive species that frequently colonize the upper respiratory tract and strongly associate with a reduced incidence of respiratory tract infections. The specific role of Cory

Putting digital innovation hubs into regional context : a European survey

While digitalisation is oftentimes thought of as a global megatrend and something that transcends national borders and geographical distances, it is at the same time a very tangible process exhibiting considerable regional and sectoral variation. Against this backdrop, Digital Innovation Hubs (DIHs) (a policy initiative in the context of the Digitising European Industry (DEI) strategy of the EU) c

Från IT till AI : digitalisering, artificiell intelligens och strukturomvandling i svensk ekonomi

Digitaliseringen och utvecklingen av en ny generation artificiell intelligens (AI) medför betydande förändring i ekonomi och samhälle. Men hur den förändringen ser ut beror inte bara på den nya tekniken, utan också på hur den till slut används. Tekniska framsteg har genom historien spelat en avgörande roll för långsiktig tillväxt och välståndsökningar, men produktivitetsökningar kommer inte gratis

A survey of cyber security in the Swedish manufacturing industry

In this paper we explore cyber security practices in Swedish manufacturing firms. Manufacturing is being trans- formed by new technologies under the label of smart industry or industry 4.0. Most of these technologies are either digital themselves or depend on digital connectivity. Their use is made possible by electronic sensors, actuators, and other devices as well as by data-driven analysis. Thi