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Measures of change in hippocampal volume derived from longitudinal MRI are a well-studied biomarker of disease progression in Alzheimer's disease (AD) and are used in clinical trials to track therapeutic efficacy of disease-modifying treatments. However, longitudinal MRI change measures based on deformable registration can be confounded by MRI artifacts, resulting in over-estimation or underestima

We examine here how issues of gender and religion are employed for ideological purposes in the discourses of radical right populist parties in Sweden and Finland. We begin with the complexity of these societies as paragons of social welfare and gender equality, within which Lutheran Christianity discreetly underpins their largely secularised character. Employing a poststructuralist methodological

Atmospheric aerosols contain organic molecules that serve as cloud condensation nucleation sites and affect the climate. Several experimental and simulation studies have been dedicated to investigate their surface propensity, but the mechanisms that drive them to the water surface are still not fully understood. In this molecular dynamics (MD) simulation study, primary alcohols are considered as a

Within the framework of the massive nonlinear sigma model extended to the next-to-leading order in the chiral counting [for corresponding to the two(-quark)-flavor Chiral Perturbation Theory], we calculate the relativistic six-pion scattering amplitude at low energy up to and including terms . Results for the pion mass, decay constant, and four-pion amplitude in the case of (meson) flavors at are

We approach critically the assertion that a referendum ultimately defends the “traditional family,” by examining the articulation of anti-gender politics in Romanian parliamentary debates. We contribute theoretically by employing the concept of retrogressive mobilization in plebiscitary circumstances. We show that in Romania the contours of retrogressive mobilization transgress both the ideologica

Pregnancy is a valuable model to study the association between DNA methylation and several cardiometabolic traits, due to its direct potential to influence mother's and child's health. Epigenetics in Pregnancy (EPIPREG) is a population-based sample with the aim to study associations between DNA-methylation in pregnancy and cardiometabolic traits in South Asian and European pregnant women and their

PURPOSE: Intrauterine undernutrition is associated with increased risk of type 2 diabetes. Children born premature or small for gestational age were reported to have abnormal retinal vascularization. However, whether intrauterine famine act as a trigger for diabetes complications, including retinopathy, is unknown. The aim of the current study was to evaluate long-term effects of perinatal famine

Diabetes increases the risk of bacterial infections. We investigated whether common genetic variants associate with infection susceptibility in Finnish diabetic individuals. We performed genome-wide association studies and pathway analysis for bacterial infection frequency in Finnish adult diabetic individuals (FinnDiane Study; N = 5092, Diabetes Registry Vaasa; N = 4247) using national register d

Resonant photoelectron spectroscopy (RPES) has been used to probe electronic structure properties of the closed-shell [FeII(CN)6]4− and open-shell [FeIII(CN)6]3− prototype transition metal complexes in aqueous solution. Site-selective Fe 2p (L-edge) RPES mapsprovide new insight into spin-coupling processes at the core-excited metal centers, with autoionization of [FeIII(CN)6]3− showing a dramatic

The ambition in this article is to present a scheme designed to facilitate an elementary analysis of political reforms. The scheme is based on six questions: Public interest or special interests? Stability or flexibility? With or against the market? Confirmation or initiation? Long or short sight? Intended or unintended consequences? There are other questions to keep in mind when evaluating reform

We present an optical design study on a nanowire heterojunction bipolar transistor solar cell. The simple structure of this novel architecture of double-junction solar cell, allows for independent power extraction from the two junctions and makes the nanowire growth easier than in current-matched double-junction solar cells as there is no need for tunnel junctions and only three main semiconductor

Context. Gaia's Early Third Data Release (EDR3) does not contain new radial velocities because these will be published in Gaia's full third data release (DR3), expected in the first half of 2022. To maximise the usefulness of EDR3, Gaia's second data release (DR2) sources (with radial velocities) are matched to EDR3 sources to allow their DR2 radial velocities to also be included in EDR3. This pre

Historiska hjälpvetenskaper bidrar till källkritik och förståelse i historisk analys. Heraldiken och genealogin är hjälpvetenskaper till historievetenskapen, men de är också hjälpvetenskaper till varandra. I denna artikel behandlas hur heraldiken kan vara en användbar hjälpvetenskap för släktforskaren. Heraldiken kan bidra till att besvara frågor om vem som utfärdade ett dokument där det finns ett

Anaphora is a study of 56 classes of vocal multiphonics that explore voiced & voiced; voiced & unvoiced; unvoiced & unvoiced, and; three or more sources. Anaphora was written for the singer Rebekka Uhlig.

The fusion-evaporation reaction 32S+28Si at 125-MeV beam energy was used to populate excited states in 55Fe. Combining the Gammasphere spectrometer with ancillary devices including the Microball CsI(Tl) array and a shell of neutron detectors, a comprehensive level scheme could be derived. The experimental results are compared with theoretical results from shell-model calculations. Taking into acco

Linking macro level political economy perspectives with micro level project-based analysis, the paper examines the impact of foreign technical assistance on urban sector projects in Egypt. The paper demonstrates how large aid flows into this sector, following Egypt's Western orientation after 1973, failed to achieve intended results. Three case studies, focusing on community development and partic

OBJECTIVE: The objectives of this study was to establish a sensitive and reproducible method to map the cartilage and subchondral bone proteomes in quantitative terms, and mine the proteomes for proteins of particular interest in the pathogenesis of osteoarthritis (OA). The horse was used as a model animal.DESIGN: Protein was extracted from articular cartilage and subchondral bone samples from thr

Hepatic failure is an important risk factor for poor outcome in septic patients. Using a chemical tagging workflow and high-resolution mass spectrometry, we demonstrate that rapid proteome remodeling of the vascular surfaces precedes hepatic damage in a murine model of Staphylococcus aureus sepsis. These early changes include vascular deposition of neutrophil-derived proteins, shedding of vascular