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Early human pregnancy serum cytokine levels predict autoimmunity in offspring.
It is generally believed that pregnancy is mediated by a Th2 response, which includes cytokines that promote placental growth and are involved in inducing tolerance to the foetus. If the balance between Th1/and Th2-mediated cytokines is disrupted, systemic and local changes could predispose the foetus to future disease. Therefore, a shift in the Th1/Th2 balance during pregnancy, possibly caused by
Recension. Hjelm, Jonny: Amasoner på planen
Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology.
This article examines the pathophysiology of lesions caused by focal cerebral ischemia. Ischemia due to middle cerebral artery occlusion encompasses a densely ischemic focus and a less densely ischemic penumbral zone. Cells in the focus are usually doomed unless reperfusion is quickly instituted. In contrast, although the penumbra contains cells "at risk," these may remain viable for at least 4 to
A new tool for predicting the probability of chronic kidney disease from a specific value of estimated GFR.
Abstract Objective. To demonstrate how patients' probability of having chronic kidney disease (CKD) stage 3-5 (measured GFR <60 mL/min/1.73 m(2)) can be predicted from a specific value of estimated glomerular filtration rate (eGFR). Material and methods. The probability of CKD stage 3-5 was predicted from a logistic regression model (n = 850) using three different eGFR prediction equations: Lund-M
Pancreatic Cancer, Healthcare Cost, and Loss of Productivity: A Register-based Approach.
BACKGROUND: Despite the fact that pancreatic cancer is the fourth leading cause of cancer-related death, there is little empirical evidence on its direct healthcare costs and, especially, its indirect costs due to loss of production. METHODS: The present study is a retrospective analysis of all patients with pancreatic cancer (excluding endocrine cancer) in the primary catchment area of Lund Unive
Changes in the ST-interval segment of the fetal electrocardiogram in relation to acid-base status at birth.
Objective To assess the occurrence of ST-interval segment changes of the fetal electrocardiogram (ECG) and cardiotocographic (CTG) abnormalities preceding acidaemia at birth. Design Case-control study. Setting University hospital labour ward. Sample Newborns with severe cord artery metabolic acidaemia (pH < 7.00 and lactate >/= 10 mmol/l; n= 24), moderate metabolic acidaemia (pH 7.00-7.09 and lact
Lund Archaeological Review 2009-2010
Is there an Islamic Public Administration Legacy in Post-Soviet Central Asia? An Ethnographic Study of Everyday Mahalla Life in Rural Ferghana, Uzbekistan
This paper examines the role of mahalla as a “hybrid” institution in the process of revamping public administration in post-Soviet Uzbekistan. It argues that the mahalla system, which is anchored on Islamic principles, has now become an institutionalized feature of Uzbekistan’s public administration (through legislative codification and executive incorporation) and now operates partly on behalf of
Paris i det fria
Artikel om European Social Forum i Paris 2003.
Marknadsföring - till vilken nytta?
The leucine-rich repeat protein PRELP binds fibroblast cell surface proteoglycans and enhances focal adhesion formation.
PRELP is a member of the leucine-rich repeat family of extracellular matrix proteins in connective tissue. In contrast to other members of the family, the amino-terminal domain of PRELP has a high content of proline and positively charged amino acids. This domain has previously been shown to bind chondrocytes and to inhibit osteoclast differentiation. Here we show that PRELP mediates cell adhesion
Possible sites of action of the new calcitonin gene-related peptide receptor antagonists.
Migraine is considered a neurovascular disease affecting more than 10% of the general population. Currently available drugs for the acute treatment of migraine are vasoconstrictors, which have limitations in their therapeutic use. The calcitonin gene-related peptide (CGRP) has a key role in migraine, where levels of CGRP are increased during acute migraine attacks. CGRP is expressed throughout the
Familial risks in understanding type 1 diabetes genetics.
Antibacterial chemokines - actors in both innate and adaptive immunity.
Several antibacterial proteins and peptides of the human innate immune system have additional roles in the regulation of adaptive immune responses. Among peptides with innate and adaptive immune functions are chemokines, a family of structurally related peptides with conserved amino-terminal motifs. Chemokines regulate leukocyte trafficking during both health and disease. In recent years, some che
Cardiovascular morbidity and mortality remain similar in two cohorts of patients with long-standing rheumatoid arthritis seen in 1978 and 1995 in Malmo, Sweden.
Objective. Patients with RA have an increased risk of cardiovascular disease. Management of RA has changed substantially over time. Our aim was to evaluate changes in cardiovascular morbidity and mortality over the period of 1978-2002. Methods. Two cohorts of consecutive patients with RA seen at outpatient clinics in Malmö, Sweden, were started in 1978 (n = 148) and 1995 (n = 161) and compared wit
Detection of Carbon-atoms In Flames Using Stimulated-emission Induced By 2-photon Laser Excitation
On José Luis Bermudez' The Paradox of Self-Consciousness
Inledningstal 19 April 2004: Finland och Sverige möts i Lund / Speech: Finland and Sweden in a European Perspective
Abstract is not available
Different assessments of immunohistochemically stained Ki-67 and hTERT in glioblastoma multiforme yield variable results: a study with reference to survival prognosis.
OBJECTIVE: To investigate a marker of tumor proliferation, Ki-67, and telomerase expression in glioblastoma multiforme and to compare the results of different mainly quantitative assessments, in relation to age and survival rates. METHODS: Immunohistochemical stainings of Ki-67 and hTERT were evaluated in 39 formaldehyde-fixed, paraffin-embedded surgical samples of glioblastoma multiforme diagnose