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VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics

Insulin resistance and lower muscle quality (strength divided by mass) are hallmarks of type 2 diabetes (T2D). Here, we explore whether alterations in muscle stem cells (myoblasts) from individuals with T2D contribute to these phenotypes. We identify VPS39 as an important regulator of myoblast differentiation and muscle glucose uptake, and VPS39 is downregulated in myoblasts and myotubes from indi

"Att famna komplexiteten" - aktionsforskning, teologi och organisatoriskt lärande

Aktionsforskning bjuder in många röster att delta i formandet av ny kunskap. I den teologiska aktionsforskningen som kapitlet beskriver, relateras de här rösterna dels till gjorda erfarenheter, dels till teologiska källor och traditioner såsom en text från evangelierna. Forskningsprocessen om lokala skeenden under flyktingmottagandet 2015 bidrar till ett organisatoriskt lärande genom ett ge rum fö

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Om Philip Pullmans His Dark Materials trilogi och relationen til hans nye Book of Dust serie.Om Philip Pullmans His Dark Materials trilogi och relationen til hans nye Book of Dust serie.

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Om Margaret Atwoods The Handmaids Tale, tv-serien af samme navn samt den nye roman The Testaments.

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Recension av Lone Hørslev: "Dagene er data" (2018) och Naja Maria Aidt: "Blå og Mørke Spor" (2018)

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Recension av Carla Lubbe: "Til rette vedkommende"

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Recension av Martin Glaz Serup: "Historien om Daniil Kharms"

Clinical significance of RBM3 expression in surgically treated colorectal lung metastases and paired primary tumours

Background The lungs are the second most common site of metastases in colorectal cancer (CRC). The aim of this study was to investigate prognostic factors, including RNA‐binding motif protein 3 (RBM3) expression, in patients with CRC treated with pulmonary metastasectomy (PM). Methods The cohort included all patients treated with PM at Skåne University Hospital, Lund, Sweden, from 2000 to 2014. C

Lung Metastases - Diagnostic, Prognostic and Molecular Aspects with Focus on Colorectal Cancer

In Sweden 4200 patients are diagnosed with lung cancer and 6500 patients with colorectal cancer (CRC) annually. The lungs are a common site for metastases. Immunohistochemistry (IHC) is a helpful aid in diagnostics of a pulmonary tumour. Selected patients with metastatic CRC undergo pulmonary metastasectomy and knowledge about which patients benefit from it is important. In this thesis IHC markers

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Recension av Richard Ford: "Kald mig Frank"

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Recension av Anne-Caroline Pandolfo and Terkel Risbjerg: "Skarabæernes konge"