This paper provides the first consistent long-run estimates of Finnish regional GDPs, from 1880 to 2010. Estimates are provided for 12 historical counties as well as for the 5 current-border NUTS 2-regions. The main results from the analyses of the long-run evolution of regional GDPs are the following. Firstly, it is clear that Finland’s geographical position, in the intersection between Eastern a

Popular Abstract in Swedish Populärvetenskaplig sammanfattning (Summary in Swedish) Syftet med de studier som ligger till grund för denna avhandling är att klarlägga den genetiska och metabola bakgrunden till typ 2 diabetes (åldersdiabetes) och dess komplikationer. Typ 2 diabetes ökar mycket snabbt i Sverige och i världen och många forskare talar om en världsomfattande diabetesepidemi. Detta är aAbstract The present study evaluated genetic and metabolic factors influencing the risk for type 2 diabetes and cardiovascular disease (CVD) with special reference to increased concentrations of free fatty acids (FFA) in 1174 Swedish diabetic and nondiabetic subjects. Common polymorphisms in the fatty acid binding protein 2 (FABP2), the B2-adrenergic receptor (B2-AR), the B3 -adrenergic receptor

Popular Abstract in Swedish Resultaten i denna avhandling visar att kvällsmåltider baserade på hela kärnor av korn (kokta kornkärnor, kornkärnbröd), har positiva effekter på blodsocker- och aptitregleringen vid den följande frukostmåltiden, jämfört med en kvällsmåltid av vitt bröd. Även ett sent kvällsmål med bruna bönor hade liknande effekter. Vidare visade resultaten att en kvällsmåltid med brunThe role of dietary fibre (DF) in disease prevention has been extensively investigated and prospective studies observed that increased DF intake decreased the risk of cardiovascular disease (CVD), reduced the risk of weight gain as well as the risk of type 2 diabetes (T2D). Also a diet characterized by low glycaemic index (GI) has been shown to reduce the risk of T2D and CVD. More recently, eviden

The issue of participation is of interest to scholars in law because of its relation to new forms of governance and regulation (Black 2000, 2001; de Burca and Scott 2006). Empirical studies of participation in biotechnology licensing show however that such procedures “itself may cause serious trouble when it is embedded in a formal procedure with a relatively strong legal framework.” (Bora & H

We discuss mass transfer in eccentric binaries containing a white dwarf and a neutron star (WD-NS binaries). We show that such binaries are produced from field binaries following a series of mass transfer episodes that allow the white dwarf to form before the neutron star. We predict the orbital properties of binaries similar to the observed WD-NS binary J1141+6545, and show that they will undergo

Popular Abstract in Swedish Inflammatoriska luftvägssjukdomar såsom astma och rinit är några av de folksjukdomar som trots den moderna läkarvetenskapen uppvisat en ökad prevalens de senaste decennierna. En allergisk reaktion och efterföljande inflammation tros ligga bakom många av de förändringar som karakteriserar astmatiska luftvägar tex infiltration av vita blodkroppar och extravasering av plasEpithelial damage may contribute to the pathology in airway diseases such as asthma and rhinitis. However, the distribution of epithelial shedding in inflammatory airway diseases and, particularly, the ensuing repair processes are largely unknown. In the present studies we have developed novel in vivo techniques to explore epithelial repair mechanisms and associated tissue responses occuring in gu

A comparisment between the historical afterlife of the Titanic disaster and the Holocaust.

Popular Abstract in Swedish Hur slutar det? Är inte detta en fråga vi ofta vill ha besvarad? Så är åtminstone fallet i min avhandling, närmre bestämt gäller det här slutet på kromosomerna, de så kallade telomererna. Telomerer definieras som den DNA/proteinstruktur som avslutar linjära kromosomer. Gener återfinns ej i denna region vilken dock har andra viktiga funktioner. Kromosomer utan telomerer Telomeres in Chironomus consist of long complex tandem DNA repeats, which in C. pallidivittatus have been shown to extend to the extreme end of chromosomes. In C. pallidivittatus the telomeric repeats are present in large blocks, 50-200kb in size, most of them belonging to four major subfamilies. The main issue of this thesis has been to elucidate possible functional roles for these different subf