PURPOSE: The aim of this study was to set up reliable and reproducible culture conditions for 3D tumoroids derived from non-small cell lung cancer (NSCLC) cell lines to enable greater opportunity for successful cultivation of patient-derived samples.METHODS: Four NSCLC cell lines, two adenocarcinomas (A549, NCI-H1975) and two squamous cell carcinomas (HCC-95, HCC-1588), were first cultured in trad

A low eGFRcystatin C/eGFRcreatinine-ratio is characteristic of a group of serious kidney disorders called ‘Selective Glomerular Hypofiltration Syndromes’. This study examines if such a low ratio can also be used to evaluate the risk for women with hypertensive disorders in pregnancy to develop severe maternal morbidity. All women discharged from the perinatal ward at the Skåne University Hospital

To analyze large, digitized corpora, we introduce the new approach of “structural reading”, which combines the abstraction of distant reading with the nuance of close reading. We do so by developing the method of “structural collocation analysis” (SCA) that uses metadata categories to investigate how research topics behave across texts belonging to different categories. The method combines the rob

Förslag på session till FEKIS2024 i KarlstadTitel: Hur kan företagsekonomi bidra till användarorienterad välfärd?Typ av session: presentationSpråk: svenskaBeräknad tidsåtgång: 45 minuterVilka som leder sessionen: Alina Lidén och Ulrika Westrup, Institutionen för tjänstevetenskap vid Lunds universitetKort beskrivning av innehållet:Välfärdsorganisationer strävar efter att utvecklas för att bättre mö

BACKGROUND: There is a growing body of evidence indicating the significant role of the immune system and immune cells in the progression of Alzheimer's disease (AD). However, the exact role of genes from various immune cell types in AD remains unclear. We aimed to utilize summary data-based Mendelian randomization (SMR) to explore the potential causal relationships between genes in specific immune

Clinical pathological diagnosis and prognosis for cancer is often confounded by spatial tissue heterogeneity. This study investigates the utility of entropy as a robust quantitative metric of spatial disorder within Fourier Transform Infrared (FTIR) chemical images of breast cancer tissue. The use of entropy is grounded in its capacity to encapsulate the complexities of pixel-wise spectral intensi

Improving the accuracy of estimated GFR (eGFR) measurement in kidney transplant recipients (KTRs) is an important goal.1 Current US and European recommendations suggest using race-free Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine-based eGFR (eGFRcr) equations (2021 age and sex [AS] or 2009 age, sex, and race–non-Black [ASR-NB]) in adults, without regard to cause or treatm

We report the discovery and characterization of a small planet, TOI-1408 c, on a 2.2 day orbit located interior to a previously known hot Jupiter, TOI-1408 b (P = 4.42 days, M = 1.86 ± 0.02 M Jup, R = 2.4 ± 0.5 R Jup) that exhibits grazing transits. The two planets are near 2:1 period commensurability, resulting in significant transit timing variations (TTVs) for both planets and transit duration

Decays of Ξb− and Ωb− baryons to Λc+h−h′− final states, with h−h′− being π−π−, K−π− and K−K− meson pairs, are searched for using data collected with the LHCb detector. The data sample studied corresponds to an integrated luminosity of 8.7 fb−1 of pp collisions collected at centre-of-mass energies s = 7, 8 and 13 TeV. The products of the relative branching fractions and fragmentation fractions for

This essay examines the Bavarian physician, mining engineer, and Catholic romantic philosopher Franz von Baader's (1765-1841) enigmatic claim that we think because we are thought with the help of the moral theologian Servain Pinckaers OP (1925-2008) and the psychologist Mihaly Csikszentmihalyi (1934-2021). Using Pinckaers' idea of 'fontal knowledge' and Csikszentmihalyi's notion of flow, I interprThis essay examines the Bavarian physician, mining engineer, and Catholic romantic philosopher Franz von Baader's (1765-1841) enigmatic claim that we think because we are thought with the help of the moral theologian Servain Pinckaers OP (1925-2008) and the psychologist Mihaly Csikszentmihalyi (1934-2021). Using Pinckaers' idea of 'fontal knowledge' and Csikszentmihalyi's notion of flow, I interpr

Measurements of the branching fraction ratio B(ϕ→μ+μ−)/B(ϕ→e+e−) with Ds +→π+ϕ and D+→ π+ϕ decays, denoted Rϕπ s and Rϕπ d, are presented. The analysis is performed using a dataset corresponding to an integrated luminosity of 5.4 fb−1 of pp collision data collected with the LHCb experiment. The branching fractions are normalised with respect to the B+ → K+J/ψ(→ e+e−) and B+ → K+J/ψ(→ μ+μ−) decay m

In this text, I develop my earlier argument on the possibility of a non-confessional theological inquiry, and hence an intellectual practice devoted to the classical theological problems that begin with reason rather than faith, at secular universities in Sweden, a country with no state church and many different religions and denominations. I answer the criticism against this tentative proposal by

The four decays, Λb0→ςc(∗)++D(∗)-K-, are observed for the first time using proton-proton collision data collected with the LHCb detector at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 6 fb-1. By considering the Λb0→Λc+D¯0K- decay as reference channel, the following branching fraction ratios are measured to be B(Λb0→ςc++D-K-)B(Λb0→Λc+D¯0K-)=0.282±0.016±0.016±0.00