In vivo knee cartilage quality assessment by direct quantification of glycosaminoglycans through chemical exchange saturation transfer (gagCEST)
Introduction: Non-invasive imaging of human articular cartilage is an important tool in understanding, and thus allowing the development of effective treatments for, osteoarthritis; a disease responsible of impaired movement of millions of otherwise healthy individuals. Glycosaminoglycans (GAG) have been attributed with important biomechanical properties, vital for the function of the articular ca