This manuscript reports the results of an international consensus on technologies of hyperthermic intraperitoneal perioperative chemotherapy (HIPEC) performed with the following goals: To provide recommendations for the technological parameters to perform HIPEC. To identify the role of heat and its application forms in treating peritoneal metastases. To provide recommendations regarding the correc

The pathophysiological mechanisms driving disease progression of frontotemporal lobar degeneration (FTLD) and corresponding biomarkers are not fully understood. Here we leveraged aptamer-based proteomics (>4,000 proteins) to identify dysregulated communities of co-expressed cerebrospinal fluid proteins in 116 adults carrying autosomal dominant FTLD mutations (C9orf72, GRN and MAPT) compared with 3

Bakgrund: Vattenfödsel erbjuds idag vid flera förlossningskliniker i Sverige till kvinnor med låg risk för förlossningskomplikationer. Trots dess växande popularitet finns fortsatt variation i tillgång, attityder och klinisk handläggning. Tidigare studier visar att barnmorskor ofta är positiva till vattenfödsel, men upplever begränsningar kopplade till riktlinjer, tekniska resurser och interprofes

Bakgrund: Trots att många kvinnor önskar föda med så få medicinska ingrepp som möjligt har användningen av interventioner vid förlossning ökat. Kvinnor idag efterfrågar även fler vårdformer än den normativa sjukhusförlossningen. Syfte: Syftet med denna kvantitativa tvärsnittsstudie var att undersöka och jämföra barnmorskors attityder till och uppfattningar om interventioner och olika vårdformer vi

With the brief of creating a solution for off-grid environments powered by solar cells, and the countless of solvable tasks existing in certain off-grid places I opted to looking at the highly populated areas of off-grid living and how the most basic needs are being met there. The meaning of off-grid is that a living space, house, or village, is self-sufficient. The living space isn’t connected to

Abstract in CzechStudie se zabývá kultem spojeným s osobností Felixe Edmundoviče Dzeržinského (1877–1926), revolucionáře a zakladatele politické policie v Sovětském svazu, a proměnami tohoto kultu v různých etapách dějin SSSR a postsovětského Ruska. Jako vedoucí nejvýznamnější represivní složky, známé pod zkratkou Čeka, stál Dzeržinskij jasně v pozadí zcela konkrétní institucionalizované podoby soThe study discusses the cult associated with the personality of Felix EdmundovichDzerzhinsky (1877–1926), a revolutionary and the founder of the political policein the Soviet Union, and the changing meanings of this cult in various stages ofthe history of the Soviet Union and post-Soviet Russia. Thanks to Dzerzhinsky, asthe head of the most significant repressive component, Soviet state terror acq

Generating electricity from solar photovoltaics (PVs) has massive potential, but realising this potential will require a genuine understanding of transaction costs associated with the adopters' acquisition of the technology. The objective of this study is thus to empirically assess the transaction costs that solar PV adopters carry when proceeding with an acquisition process. Data on transaction c

Människor har skapat arkiv i över 4 000 år – för att organisera tillvaron, förstå omvärlden och föra kunskap vidare. Arkiven präglas av sin tids värderingar, men de utgör också de mest trovärdiga källorna till historien, skriver företrädare för Universitetsbiblioteket i Lund, Statens musikverk och Svenska Unescorådet .

När president Trump nyligen fryste drygt 2 miljarder dollar i forskningsmedel till Harvard University var det ett strategiskt drag i en större kamp för att forma akademin politiskt. Att ledningen på Harvard står upp för sin frihet är både modigt och nödvändigt för att forskning alls ska kunna vara fri framöver. När Trump stryper Harvards och andra universitets finansiering, visar han med all önskv

This study investigates the potential of personal cooling solutions to mitigate heat stress in outdoor sporting environments. As global temperatures continue to rise, heat stress has become an increasing concern, particularly in urban environments where outdoor sport can cause significant thermal discomfort. A mixed methods approach was used, including online research, an experimental cooling stud

Det finns ett växande intresse för den roll som lokala aktörer spelar i utformningen av regionala utvecklingsbanor i mindre, perifera regioner. Men, när de strukturella förutsättningarna är begränsade eller ogynnsamma begränsas dock möjligheterna för lokala aktörer. I denna artikel kombinerar vi begreppen agens och möjlighetsutrymme med en processmodell för adaptiva cykler för att identifiera när,There is a growing interest in the role of agency in shaping regional development paths in smaller, peripheral regions. However, when structural pre-conditions are limited or unfavourable, opportunities for local actors are constrained. In this paper, we combine the concepts of agency and opportunity space with a process-model of adaptive cycles in order to identify when, how, and why local actors

Digital traces representing online consumer practices: A methodologicalguidance for exploratory retailing researchPatrik Stoopendahl11 Stockholm School of Economics Institute for Research (SIR)Extended abstractDigital devices, such as the smartphone, enable an array of tasks in consumers’ daily lives; searching forproducts, soliciting advice from friends, interacting with communities or retailers,

The Versatile Touchpoint: User-Generated Content Reshaping theCustomer JourneyAUTHORS1, Affiliation; 2, Affiliation; 3, Affiliation; 4. AffiliationKeywordsIntroductionCustomer Journey; User Generated Content; Social Media; Touchpoint; Brand PublicsIn this study we seek to unravel the emergence of a touchpoint that has become ubiquitousthroughout the customer journey due to social media. We are esp

Quantum mechanics has been enormously successful. The equations and rules enable accurate calculations and predictions of energies and other properties of atoms, molecules, and materials. Quantum-physics-based technology is an integrated part of our daily lives. Still, the understanding and interpretation of quantum physics offer many challenges, with the counterintuitive consequences of the rules

We introduce a new database of historical Genuine Savings (GS), an indicator of sustainable development promoted by theWorld Bank and widely used in contemporary economic research. GS derives from the theoretical work on wealth accounting, and addresses shortcomings in conventional metrics of economic development by incorporating broader measures of saving and investment, including human capital (

Quantum information science has leaped forward with the exploration of high-dimensional quantum systems, offering greater potential than traditional qubits in quantum communication and quantum computing. To advance the field of high-dimensional quantum technology, a significant effort is underway to progressively enhance the entanglement dimension between two particles. An alternative effective st