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Anemia in patients ten years after bariatric surgery

Background: More than 10% of the global population has a BMI above 35. Bariatric surgery is an efficient way to treat this condition. Unfortunately, there is a risk of nutritional deficiencies. The number of studies after a longer time span is scarce. The aim of this study was to determine the occurrence of anaemia five and ten years after bariatric surgery and how it was related to substitution t

Everything-cleft constructions in spoken British English : A neglected construction

Within the framework of Construction Grammar, this study examines constructions with a cleft form containing everything, e.g., that’s everything that’s happened, in spoken British English, using the London-Lund Corpora and the British National Corpora. We trace the development of everything-clefts in recent history and make comparisons with all-clefts since both all and everything express totality

Optimization of Drying Parameters for Pretreated Green Banana Slices Using Response Surface Methodology

In this study, the influence of drying temperature and pretreatment on the drying kinetics and quality metrics of green banana slices was investigated. The present investigation included the drying of 4 ± 1 mm green banana slices with potassium metabisulfite (KMS) at levels of 0 (control), 0.5%, 1%, and 1.5% in a tray dryer. A numerical optimization method was utilized to optimize the drying rate,

When Are Single Reader Evaluations Insufficient in Teledermoscopic Assessments? : Analyses of a Retrospective Cohort Study

Background: Teledermoscopy (TDS) emerges as an efficient tool for diagnosing skin lesions. In Sweden, double reading is the standard of care, but risk factors for misdiagnosis or mismanagement using single reader evaluations (SRE) are not well-studied. This study aimed to assess the accuracy of SRE compared with the gold standard in TDS. Methods: This retrospective cohort study involved 1,997 TDS

Histopathological Diagnostic Discordance between Punch Biopsies and Final Diagnostic Excisions of Cutaneous Squamous Cell Carcinoma : Analysis of 737 Cases

The recommended treatment for cutaneous squamous cell carcinoma is surgical excision. An initial punch biopsy is often performed as an aid to diagnosis. A retrospective registry-based study was performed to assess histopathological concordance of punch biopsy of cutaneous squamous cell carcinoma and subsequent excision. Analysis of 737 punch biopsies and subsequent matched excisions was performed.

Breast cancer and its genetic heterogeneity at single cell level: A concise perspective of cellular architecture and taxonomy

Dealing with the heterogeneity of breast tumors and treating breast cancer patients pose a great challenge. The heterogeneity within and between tumors indicates that each case of breast cancer may have a good prognosis and could benefit from tailored therapies. Breast cancer is a condition that undergoes changes as the tumor progresses and metastasizes, which presents further challenges for imple

Physical health in young males and risk of chronic musculoskeletal, cardiovascular, and respiratory diseases by middle age : A population-based cohort study

BACKGROUND: Cardiovascular, respiratory, and musculoskeletal disease are among the leading causes of disability in middle-aged and older people. Health and lifestyle factors in youth have known associations with cardiovascular or respiratory disease in adulthood, but largely unknown associations with musculoskeletal disease.METHODS AND FINDINGS: We included approximately 40,000 18-year-old Swedish

Inferring North American Holocene Land Cover Change using Paleoecological Evidence

Climate-vegetation feedbacks (CVFs) can amplify or mitigate climate variations. These feedbacks operate at multiple timescales. Fast processes such as leaf-scale carbon fluxes operate at sub-annual timescales, while slow processes, driven by changes in forest composition and structure, occur over decadal and longer timescales. Slow processes are rarely directly observed from instrumental data; yet

Holocene Land Cover Change in North America: Trends, Drivers, and Feedbacks

Land cover governs biogeophysical and biogeochemical feedbacks between the land surface and atmosphere. Holocene vegetation-atmosphere interactions are of particular interest, both to understand the climate effects of intensifying human land use and as a possible explanation for the Holocene Conundrum, a widely studied mismatch between simulated and reconstructed temperatures. Progress addressing

Deep Learning for Resolving 3D Microstructural Changes in the Fibrotic Liver

Portal hypertension, a life-threatening complication of cirrhosis,is largely triggered by increased intrahepatic vascular resistance.Fibrosis, regenerative nodule formation, intrahepatic angiogenisis and sinusoidalremodelling are classical mechanisms that account for increasedintrahepatic vascular resistance in cirrhosis. Our study leverages highresolution3D synchrotron radiation-based microtomogr

Conceptual design of a 3rd harmonic cavity system for the LNLS electron storage ring

The installation of a second RF cavity in the UVX electron storage ring at the Brazilian Synchrotron Light Laboratory (LNLS) at the end of 2003 brought about longitudinal instabilities driven by one of the HOMs of the new cavity. Even though the operational difficulties related to these unstable modes were successfully overcome by means of a combination of cavity tuning (using temperature and plun