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The Initial Interview in Palliative Care Consultation
The initial interview is a critical moment in the relationship between the patient and the palliative care team. Good communication skills, while always important in clinical medicine, are especially indispensable in this context, where a life-threatening illness and associated fear, anxiety, sadness, and hope can make for a challenging clinician-patient relationship. When done expertly, the initi
”Vi har bara det vatten vi har.” : Vattenhantering mellan vardagspraktik och framtidsvision
Vårt bidrag tar utgångspunkt i hur innovativa avlopps- och vattenhanteringspraktiker samspelar i en urban kontext. Det empiriska materialet har hämtats från ett tvärvetenskapligt forskningsprojekt om innovativ vattenhantering i en stad i Sverige. Artikeln analyserar på ett övergripande plan samtida idéutveckling vad gäller återvinning av avloppsvatten och hur denna idéutveckling producerar olika f
Clinician attitudes towards adoption of evidence‑based practice: A nationwide multiprofessional cross‑sectional study of child and adolescent mental health services in Sweden
Background Implementation of evidence-based practice (EBP) in child and adolescent mental health services (CAMHS) is a priority to improve service delivery and outcomes. Clinicians’ EBP attitudes are likely to play a crucial role in implementation but are poorly understood. This study aimed to assess variation in EBP attitudes in a large national sample of CAMHS clinicians in Sweden, and to compar
Using Augmented Reality to Strengthen Consumer/Brand Relationships: The Case of Luxury Brands
Though augmented reality (AR) is increasingly adopted in marketing, its capacity to foster consumers' engagement and attachment remain tenuous, exposing an important literature-based gap. Addressing this gap, we deploy social presence theory and luxury consumption theory to develop and test a model that proposes that consumers' engagement with AR-deploying luxury brands drives the development of t
Natural marine aerosols : A study on atmospheric chemistry, new particle formation and particle growth
The role of natural marine aerosols in the global climate system remains understudied and uncertain. This is true for the emissions of natural volatile compounds over the ocean, the oxidation of said compounds and their impact on particle formation and particle growth. In this thesis, the emission, chemistry and aerosol particle processes relating to these compounds were studied using different pr
Modelling the resource circularity gap with preparation for reuse flows using a generic material flow analysis framework
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Biallelic variants in RINT1 present as early-onset pure hereditary spastic paraplegia
Male-biased recombination at chromosome ends in a songbird revealed by precisely mapping crossover positions
Recombination plays a crucial role in evolution by generating novel haplotypes and disrupting linkage between genes, thereby enhancing the efficiency of selection. Here, we analyze the genomes of 12 great reed warblers (Acrocephalus arundinaceus) in a 3-generation pedigree to identify precise crossover positions along the chromosomes. We located more than 200 crossovers and found that these were h
Frequent hemodialysis versus standard hemodialysis for people with kidney failure : Systematic review and meta-analysis of randomized controlled trials
Background Frequent hemodialysis provided more than three times per week may lower mortality and improve health-related quality of life. Yet, the evidence is inconclusive. We evaluated the benefits and harms of frequent hemodialysis in people with kidney failure compared with standard hemodialysis. Methods We performed a systematic review of randomized controlled trials including adults on hemodia
The role of exercise training on cardiovascular risk factors and heart disease in patients with chronic kidney disease G3-G5 and G5D : a Clinical Consensus Statement of the European Association of Preventive Cardiology of the ESC and the European Association of Rehabilitation in Chronic Kidney Disease
Cardiovascular (CV) morbidity and mortality is high in patients with chronic kidney disease (CKD). Most patients reveal a high prevalence of CV risk factors such as diabetes or arterial hypertension and many have manifest cardiovascular disease (CVD), such as coronary artery disease and chronic heart failure with an increased risk of clinical events including sudden cardiac death. Diabetes mellitu
Localized and Long-Lasting Adaptation in Dragonfly Target-Detecting Neurons
Some visual neurons in the dragonfly (Hemicordulia tau) optic lobe respond to small, moving targets, likely underlying their fast pursuit of prey and conspecifics. In response to repetitive targets presented at short intervals, the spiking activity of these “small target motion detector” (STMD) neurons diminishes over time. Previous experiments limited this adaptation by including intertrial rest
Band terminations and maximum spin values with up to 18 aligned particles (and holes) in the Z,N=50 to 82 shells
Observed rotational bands that terminate or appear to terminate at very high spin are analyzed within the configuration constrained cranked Nilsson-Strutinsky (unpaired CNS or CNSB with pairing) formalism. Spin values for the nuclei discussed reach or come close to the maximum spin that can be built within the Z,N=50-82 shells. Configurations are distinguished not only by the number of particles i
Immune system adaptation during gender-affirming testosterone treatment
Infectious, inflammatory and autoimmune conditions present differently in males and females. SARS-CoV-2 infection in naive males is associated with increased risk of death, whereas females are at increased risk of long COVID1, similar to observations in other infections2. Females respond more strongly to vaccines, and adverse reactions are more frequent3, like most autoimmune diseases4. Immunologi
HMGA1 stimulates cancer stem-like features and sensitivity to monensin in gastric cancer
Gastric cancer represents a serious health problem worldwide, with insufficient molecular biomarkers and therapeutic options. Consequently, several efforts have been directed towards finding specific disease markers in order to develop new therapies capable of defeating gastric cancer. Attention has been pointed to cancer stem cells (CSCs) as they are primarily responsible for tumor initiation and
Capacity for the management of kidney failure in the International Society of Nephrology Western Europe region : report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA)
Western Europe boasts advanced health care systems, robust kidney care guidelines, and a well-established health care workforce. Despite this, significant disparities in kidney replacement therapy incidence, prevalence, and transplant access exist. This paper presents the third International Society of Nephrology Global Kidney Health Atlas's findings on kidney care availability, accessibility, aff
Peer-to-peer training among health care professionals working in dialysis clinics : an education approach from the GoodRENal project
Background: Lifestyle interventions aiming to improve dietary habits, increase physical activity level, and improve emotional well-being can positively impact clinical outcomes in patients with chronic kidney disease (CKD). Educational material for health care professionals working with CKD patients that focuses on why and how to promote lifestyle changes is lacking. The present study aims to depi
Assisted peritoneal dialysis compared to in-centre hemodialysis – an observational study of outcomes from the Swedish Renal Registry
Background: In-center hemodialysis (IHD) is the most common dialysis modality. Assisted peritoneal dialysis (assPD) is an option for frail and/or incapacitated patients. Both modalities can be used to alleviate uremic symptoms towards the end of life. There are few studies comparing these modalities. The primary aim is to compare hospital admissions between assPD and IHD. The secondary aim is to c
Tumor purity estimated from bulk DNA methylation can be used for adjusting beta values of individual samples to better reflect tumor biology
Epigenetic deregulation through altered DNA methylation is a fundamental feature of tumorigenesis, but tumor data from bulk tissue samples contain different proportions of malignant and non-malignant cells that may confound the interpretation of DNA methylation values. The adjustment of DNA methylation data based on tumor purity has been proposed to render both genome-wide and gene-specific analys