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The innate immune system is the first line of defense against invading microbes. Its specificity relies a great deal on host pattern recognition molecules that sense pathogen-associated molecular patterns of the invading pathogen. However, full protection is not always guaranteed, and some early defense mechanisms involved in bacterial killing, such as the complement system, can also exert cytolyt

Definition of individual risk profile is the first step to implement strategies to keep the delicate balance between under- and overimmunosuppression after kidney transplantation.

A measurement of the Lambda(0)(b) lifetime and mass in the decay channel Lambda(0)(b) -> J/psi (mu(+) mu(-))Lambda(0)(p pi(-)) is presented. The analysis uses a signal sample of about 2200 Lambda(0)(b) and (Lambda) over bar (0)(b) decays that are reconstructed in 4.9 fb(-1) of ATLAS pp collision data collected in 2011 at the LHC center-of-mass energy of 7 TeV. A simultaneous mass and decay time ma

It is widely believed that the light induced degradation of crystalline silicon solar cells is due to the formation of a BsO2i recombination center created by the optically excited migration of the oxygen dimer (charge-state-driven motion). In this letter the concentration dependence of the neutral state of O-2i on [O-i] in p- and n-type Cz-Si has been determined using infrared absorption. A syste

Combining experiment and theory, evidence from surface-enhanced Raman scattering (SERS) were obtained for p,p'-dimercaptoazobenzene (DMAB) produced from p-aminothiophenol (PATP) by selective catalytic coupling reaction on silver nanoparticles. The time-dependent SERS spectra of PATE are consistent with the calculated SERS spectra of DMAB), which is the direct evidence or the production of DMAB fro

For the past several decades, we have been able to directly probe the motion of atoms that is associated with chemical transformations and which occurs on the femtosecond (10(-15)-s) timescale. However, studying the inner workings of atoms and molecules on the electronic timescale(1-4) has become possible only with the recent development of isolated attosecond (10(-18)-s) laser pulses(5). Such pul

Correlations of two charged identical kaons (KchKch) are measured in pp collisions at root s = 7 TeV by the ALICE experiment at the Large Hadron Collider (LHC). One-dimensional (KKch)-K-ch correlation functions are constructed in three multiplicity and four transverse momentum ranges. The (KKch)-K-ch femtoscopic source parameters R and lambda are extracted. The (KKch)-K-ch correlations show a slig

We study how general two Higgs doublet models can be constrained by considering their properties under renormalization group evolution of the Yukawa couplings. We take into account both the appearance of a Landau pole as well as off-diagonal Yukawa couplings leading to flavour changing neutral currents in violation with experimental constraints at the electroweak scale. We find that the latter con

Patients with multiple myeloma (MM) have an increased risk of fractures. On the basis of small numbers, patients with monoclonal gammopathy of undetermined significance (MGUS) have been reported to have an increased fracture risk. Using population-based data from Sweden, we assessed the risks of fractures in 5326 MGUS patients diagnosed from 1958 to 2006, compared with 20 161 matched controls. MGU

Quinoline-3-carboxamide compounds (Q compounds) have demonstrated efficacy in treating autoimmune disease in both humans and mice. However, the mode of action of these compounds is poorly understood. Here, we show that preventive treatment with the Q compound paquinimod (ABR-215757) during the first 5 days after induction of experimental autoimmune encephalomyelitis is sufficient to significantly

Most microlevel studies in the social sciences have focused on the impact of different measured variables. While some studies have also dealt with unobserved variation, it has usually only been controlled for to perfect the estimates of the observables. In this article, the authors applied a modified version of a recently developed method designed to quantify the effect of unobserved variation in

Three incommensurately modulated gamma-brass-related composite structures in the Ni-Zn system have been solved from Xray single crystal diffraction data using a 3+1 dimensional super space description. The compounds at the end points of the compositional domain NiZn3-delta (-0.09 <= delta <= 0.34) and NiZn3.30 crystallize in the orthorhombic superspace group Fmmm(alpha 00) 0s0 {F = [(1/2, 1/2, 0,

A commonly practiced method intended to reduce mortality from recreational fisheries is mandatory (e.g., small fish protected by minimum-size limits) or voluntary catch-and-release (C&R), where fish are caught with hook and line and released alive on the assumption that fish survive unharmed. C&R can, however, have both lethal and sub-lethal consequences for fish, with altered behaviour se

Studies of antibiotic prescribing related to diagnosis comparing prescribers trained abroad with those trained in Sweden are lacking.

The impacts of swells on the atmospheric boundary layer (ABL) flows and by this on the standalone offshore wind turbine (WT) performance are investigated by using large eddy simulations (LES) and actuator-line techniques. At high swell to wind speed ratio, the swell-induced stress reduces the total wind stress resulting in higher wind velocity, less wind shear, and lower turbulence intensity level

Crystal plasticity models are often used to model the deformation behavior of polycrystalline materials. One major drawback with such models is that they are computationally very demanding. Adopting the common Taylor assumption requires calculation of the response of several hundreds of individual grains to obtain the stress in a single integration point in the overlying FEM structure. However, a

Throughout human history, people have coped with, and adapted to, their environment. This accumulated capacity at local level is increasingly recognized to be critical in improving resilience and transformation. Nevertheless, city dwellers’ coping and adaptive practices are little known, poorly documented and often not taken into account in the work of municipal authorities and aid organizations.