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Breast cancer is the most common type of cancer worldwide. Diagnosing breast cancer relies on clinical examination, imaging and biopsy. A core-needle biopsy enables a morphological and biochemical characterization of the cancer and is considered the gold standard for breast cancer diagnosis. A histopathological examination uses high-resolution microscopes with outstanding contrast in the 2D plane,
In this essay we put forward a critique of the prevailing orthodoxy of creativity and innovation which are rarely fundamentally questioned neither in science nor in public discourse. We urge to reconsider contemporary purposes and consequences of what we call instrumental and humanist conceptions of creativity and innovation. Based on our critique we speak out to transcend reified notions of creat
Construction of historical national accounts has a long history in Sweden. It started in the interwar period and later a number of improvements and extensions backward and forward in time have been made. Thus, now there are series from 1300 onwards. Of course, due to limitations of the source material, the estimates are more and more uncertain the further back in time they refer to. In this paper
Many individuals are experiencing the potentially stressful combination of providing care while still employed. In this study, the association between unpaid caregiving to another adult and self-reported stress among men and women aged 45–74 is investigated, using nationally representative time use diary data for Sweden (2000-01 and 2010–11, N = 6689). Multivariate regression analyses established
Kinas utveckling framöver har lika uppenbara som stora implikationer för svenska företag. Nu gäller det att anpassa sig till de föränderliga globala förutsättningarna för att säkerställa långsiktig framgång, skriver Björn Cappelin, biträdande chef, Nationellt kunskapscentrum om Kina, Tommy Shih, docent, Lunds universitet och Fredrik Sjöholm, professor och vd, Institutet för Näringslivsforskning (I
To differentiate between medical malpractice and expected, but rare, medical complication in a medicolegal autopsy context is often difficult. Such an assessment requires knowledge about the clinical practice associated with the procedure at hand, and that findings of the autopsy, including medical relevant information such as patient chart, radiological imaging, and statements from witnesses abou
Introducing seaweed to new food markets entails new challenges concerning efficient preservation. Hence, this study explores high-pressure processing (HPP) as an alternative technique to conventional methods by evaluating its effects on the composition, quality, and microbial safety of the Swedish grown macroalgae Saccharina latissima. The results from the physicochemical analysis showed that afte
OBJECTIVES: Early onset ataxia (EOA) concerns a heterogeneous disease group, often presenting with other comorbid phenotypes such as myoclonus and epilepsy. Due to genetic and phenotypic heterogeneity, it can be difficult to identify the underlying gene defect from the clinical symptoms. The pathological mechanisms underlying comorbid EOA phenotypes remain largely unknown. The aim of this study is
Histatin 5 is a histidine-rich, intrinsically disordered, multifunctional saliva protein known to act as a first line of defense against oral candidiasis caused by Candida albicans. An earlier study showed that, upon interaction with a common model bilayer, a protein cushion spontaneously forms underneath the bilayer. Our hypothesis is that this effect is of electrostatic origin and that the obser
Coarse-graining is commonly used to decrease the computational cost of simulations. However, coarse-grained models are also considered to have lower transferability, with lower accuracy for systems outside the original scope of parametrization. Here, we benchmark a bead-necklace model and a modified Martini 2 model, both coarse-grained models, for a set of intrinsically disordered proteins, with t
The aim of this article is to shed light on how sensory perceptions are communicated through authentic language. What are the language resources available to match multimodal perceptions, and how do we use them in real communication? We discuss insights from previous work on the topic of the interaction of perception, cognition, and language and explain how language users recontextualise perceptio
This chapter focuses on the concepts that have driven the development of Artistic Research in the Nordic countries. Acknowledging, like other regional perspectives, that there are many differences between countries and programmes within them, the chapter aims to bring out key issues informing Artistic Research. In particular, it sheds light on the disposition to include the quality of the arts pra
Elevated levels of neutrophil extracellular traps (NETs) have been reported in primary graft dysfunction, making methods to reduce or remove them highly valuable. The mechanisms behind primary graft dysfunction remain rudimentarily understood but its relation to higher rates of acute and chronic rejection necessitates the development of preventative treatments. This case series explores the use of
Databases are increasingly used in international law settings. This requires new strategies for those who want to critique international legal practices and their effects. In this essay, we claim that legal scholarship tends to conceptualize the database in ways that leave older and inadequate ideas of legal method(s) and sovereignty in the context of international law largely unquestioned or even
