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Elevations in plasma glucagon are associated with reduced insulin clearance after ingestion of a mixed-macronutrient meal in people with and without type 2 diabetes

Aims/hypothesis: The temporal suppression of insulin clearance after glucose ingestion is a key determinant of glucose tolerance for people without type 2 diabetes. Whether similar adaptations are observed after the ingestion of a mixed-macronutrient meal is unclear. Methods: In a secondary analysis of data derived from two randomised, controlled trials, we studied the temporal responses of insuli

Förintelseforskningen i Norden : Från historiskt undantag till demokratisk grundton

Something that all Nordic countries have in common is that journalistic work, popular culture phenomena and public debates resulting in subsequent political initiatives have served as driving forces in the development of academic research on the Holocaust. It is also clear that the field is heavily politicized, imbued with moral questions and highly diversified.The memories of the Holocaust have i

Asynchronous Real-Time Federated Learning for Anomaly Detection in Microservice Cloud Applications

The complexity and dynamicity of microservice architectures in cloud environments present substantial challenges to the reliability and availability of the services built on these architectures. Therefore, effective anomaly detection is crucial to prevent impending failures and resolve them promptly. Distributed data analysis techniques based on machine learning (ML) have recently gained attentionThe complexity and dynamicity of microservice architectures in cloud environments present substantial challenges to the reliability and availability of the services built on these architectures. Therefore, effective anomaly detection is crucial to prevent impending failures and resolve them promptly. Distributed data analysis techniques based on machine learning (ML) have recently gained attention

Crack growth rates for short fatigue cracks in the vicinity of a low angle grain boundary

The interaction between a low angle grain boundary in front of a crack tip and the emerging plasticity from the tip of a microstructurally short edge crack subjected to fatigue loading has been studied. The modeling rests solely on discrete dislocations, were the geometry is described by dislocation dipole elements in a boundary element approach and the plasticity, restricted to one slip plane, to

Comparison between fatigue crack growth modelled by continous dislocation distributions and discrete dislocations

Short fatigue cracks are known to have a growth behaviour different from that of long cracks, the latter well predicted by linear elastic fracture mechanics. Short cracks can grow at high rates at load levels well below the threshold value for long cracks, before entering into the long crack region, or arrest and become nonpropagating cracks. The growth behaviour of short cracks is strongly influe

‘Proxy Parenting’ and Creating a ‘Golden Touch’. : Practices and Discourses of Intensive Grandparenting.

Grandparents’ involvement in their adult children’s families has increased in recent decades, especially in relation to care arrangements around grandchildren. This ‘new army of proxy parents’ calls for the need to critically analyse grandparental care. Drawing on a study on intergenerational care in Sweden, involving grandparents, adult children and grandchildren (63 interviewees including 28 graGrandparents’ involvement in their adult children’s families has increased in recent decades, especially in relation to care arrangements around grandchildren. This ‘new army of proxy parents’ calls for the need to critically analyse grandparental care. Drawing on a study on intergenerational care in Sweden, involving grandparents, adult children and grandchildren (63 interviewees including 28 gra

Fatigue crack growth in the vicinity of a grain boundary modelled using a discrete dislocation technique

It is well known that the behaviour of short cracks differs from that of long cracks due to the relatively large plastic zone and strong influence from the surrounding microstructure, and for very low growth rates, it is important to account for discrete dislocations within the material. In this study, a discrete dislocation model is presented for the study of the growth behaviour of a short edge

Cell types or cell states? An investigation of adrenergic and mesenchymal cell phenotypes in neuroblastoma

Neuroblastoma exhibits two cellular phenotypes: therapy-sensitive adrenergic (ADRN) and therapy-resistant mesenchymal (MES). To understand treatment response, it is important to elucidate how these phenotypes impact the dynamics of cancer cell populations and whether they represent distinct cell types or dynamic cell states. Here, we use an integrated experimental and mathematical modeling approac

Clinical guidelines for the management of mammographic density : a systematic review of breast screening guidelines worldwide

Background: High breast density is an independent risk factor for breast cancer and decreases the sensitivity of mammography. This systematic review synthesizes the international clinical guidelines and the evidence base for screening and supplemental screening recommendations in women with dense breasts. Methods: A systematic search of CINHAL, Embase, and Medline databases was performed in August

Novel insights into the cognitive, emotional, and experiential dimensions of stakeholder acceptance of wildlife management

Understanding wildlife stakeholders is vital in mitigating the risk for inertia in the implementation of management and illegal activities, e.g., poaching. We used a unique set of questionnaire data of stakeholders in Sweden (n = 8728) comprising birdwatchers, hunters, farmers, and the general public, to analyze evaluations of geese, beliefs about goose management at multiple levels, and acceptanc

(De)colonial Sweden in the world : An email conversation

This chapter reflects on the need for a decolonial turn in Sweden’s foreign policy. The growing ecological emergencies that we are faced with call on us to recognise and address quite profound global inequities, many of which are rooted in histories of European colonialism. In a sprawling conversation about the coloniality of the global economy and Sweden’s role in it, the chapter addresses such t

Visuo-Locomotive Complexity as a Component of Parametric Design for Architecture : 8th International Conference on Research into Design (ICoRD 2021, Online Conference), IDC School of Design, IIT Bombay, Mumbai, India, January 7-10, 2021

A people-centred approach for designing large-scale built-up spaces necessitates systematic anticipation of user’s embodied visuo-locomotive experience from the viewpoint of human-environment interaction factors pertaining to aspects such as navigation, wayfinding, usability. In this context, we develop a behaviour-based visuo-locomotive complexity model that functions as a key correlate of cognit

Evaluating carbon removal : Integrating technical potential with environmental, social, governance criteria, and sequestration permanence

Climate modeling suggests that achieving international climate goals requires a reduction in current CO2 emissions by over 90%, with any remaining emissions to be addressed through carbon dioxide removal (CDR) solutions. Sixteen CDR strategies are evaluated by integrating technical potential, environmental, social, and governance (ESG) criteria, along with sequestration permanence. This evaluation

Surgical treatment and outcomes in aortic valve endocarditis and perivalvular abscesses

Patients with aortic root abscesses experience increased morbidity and mortality compared to those without abscess in aortic valve infective endocarditis. The superior intervention for patients with aortic root abscess is not determined. This research investigates the degree to which increased morbidity and mortality of aortic root abscess, and to describe perioperative characteristics and outcome