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When Britain decided, in 1968, to terminate its official colonial presence in the Persian (Arabian) Gulf as of 1971, this action prompted the Gulf Arab States (Kuwait, Bahrain, Saudi Arabia, Qatar, United Arab Emirates, and Oman) to start the search for a form of partnership that would bring them together to better cope with the insecurity and danger surrounding them and their regimes. A key probl
Starch microsphere is a dosage form suitable for the encapsulation of protein drugs. The starch microspheres investigated in this thesis are intended for release of the drug in a pre-designed way, or in controlled manner. For this purpose the starch microspheres can be coated by poly(DL-lactide-co-glycolide) (PLG) film, which is a release controlling. The term microsphere quality is complicated an
This thesis deals with the development of novel methodologies for the synthesis of hetero- and carbocycles enabled by transition metal catalysis. The second chapter of the thesis describes a gold-catalyzed three-component reaction to form a variety of substituted oxazoles from readily available N-benzylimines, terminal alkynes, and acyl chlorides. Sacrificial benzyl groups are used to merge two o
This study investigates the interaction between dendritic cells (DC) and the Gram negative intracellular bacterium Salmonella typhimurium. Using in vitro and in vivo approaches, the capacity of DC to directly and indirectly present antigens from Salmonella-infected cells, cytokine production by infected DC, and activation of bacteria-specific T cells was analyzed. These studies revealed differenti
Neuroleptic maintenance treatment is effective to reduce the risk of further episodes of schizophrenia and other chronic psychoses, except affective. Lack of insight often lead to poor compliance to the prescripted medication. Then, neuroleptics might be given as depot injections. A group of chronic psychotic outpatients were assessed of clinical symptoms and side effects regularely during the th
The work presented in this thesis deals with metallacyclic late transition metal complexes, obtained by intramolecular Csp3-H activation, and the application of such compounds in catalysis. The new hemilabile P,O phosphines N-methyl-N-propionyl-2-(diphenylphosphino)benzylamine (DPPAM), o-(diphenylphosphino)benzoic acid ethyl ester (DPPES), o-(diphenylphosphino)benzoic acid methyl ether (DPPET) and
Bacillus subtilis is a model organism for endospore-forming gram-positive bacteria. Endospores are formed in response to nutrient starvation. They can resist harsh environments and last for long periods of time. Once nutrients again become available, the endospore can germinate and the vegetative life cycle be resumed. The outermost layers of the endospore are cortex and coat that protect the cell
Cancer is a complex and heterogeneous disease where cells have started to grow uncontrolled and this disease remains a major health problem. Because of diffuse symptoms it often presents at a late stage. Insufficient understanding of the different phenotypes hinders the development of targeted therapeutics and consequently patients show a diverse range of responses to a given treatment. This thes
Genetic information, which is stored in DNA, is transferred to messenger RNA (mRNA) in a process called transcription. mRNAs are then translated by ribosomes into proteins which, with some important exceptions, catalyze chemical reactions in cells. Since cells must be able to adapt to changes in the environment, mRNAs must be unstable. The present investigation concerns mRNA degradation mainly in
Hemicelluloses are tremendous sources of renewable raw materials, which utilisation have the potential to be highly increased in the future. Hemicelluloses are among the major groups of compounds in plant cell walls, together with cellulose and lignin. These three components are closely associated, making them difficult to separate from each other. Hemicelluloses are complex polysaccharides and tw
This thesis offers an investigation of the literary form and the literary composition of The Ladder by John Climacus, as well as a study of how the author uses the tradition to form his reader. Besides a brief introduction with a survey of the previous research, the study comprises four chapters. In the first chapter it is shown, from a number of detailed text analyses, that the material in the s
Stream ciphers are cryptographic primitives used to ensure privacy in digital communication. In this thesis we focus on stream ciphers built using Linear Feedback Shift Registers (LFSRs). Several different stream ciphers are analysed and new attacks are presented. In addition, two new stream ciphers are presented, both based on the same design. The first attack is performed on SOBER-t16 and SOBER
Most animals use eyes to guide their behaviour. Analysing, and understanding, visually guided behaviours gets more complicated the more advanced the animal gets. Box jellyfish provide a relatively simple system for understanding visually guided behaviours. They have a limited nervous system, but they also possess a visual system that is quite impressive for a jellyfish. Box jellyfish have 24 eyes
Locating and evaluating a suitable partner for mating is one of the most important events in any sexually reproducing organism. To achieve this, an animal must be able to locate its partner over both long and short distances, and finally evoke the proper mating behaviour. This is made possible by use of conspecific signals picked up by one or several sensory systems, the most well investigated bei
This thesis concerns a religious actor in the civil society in times of violent conflict. During the British Mandate period in Palestine, Jewish, Muslim and Christian children studied together at Anglican missionary schools. At this time Jerusalem bore all the imprints of ethnic and religious separation and division. The Anglican educational project became part of the efforts made by the Anglican
The aim of this dissertation is to explore some of the problems associated with introducing authentic assessment in teacher education. In the first part of the dissertation the question is investigated, through a literature review, whether the use of scoring rubrics can aid in supporting credible assessment of complex performance, and at the same time support student learning of such complex perfo
Diabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. This is accomplished by insulin injections. Even though the treatment methods have been improve
The aim of this dissertation is to discuss the two theologic anthropological concepts microcosm and steward within the World Council of Churches project called the JPIC-process - their JPIC stands for justice, peace and the integrity of creation - and to relate the two anthropological concepts to each other using a theological correlation method. After an introduction the JPIC-process, which offic
Traditional off-line programming is not enough in order to use the full potential of virtual models and simulation system in industrial robot applications. The interface between off-line programming system and the robot controller is today restricted to program transfer. In this way a large amount of information is lost since typical robot programming languages is rather limited. If the virtual m
The link between population mobility and environmental change is fundamental for our understanding of how future global environmental changes will affect our societies, and also how the increased mobility will change our role in the Earth system. Climate change has been predicted as a major cause of human migration, both voluntary and forced, through for example increased storm and drought frequen
