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By using ancient texts, medieval documents, philological observations, and archaeological artifacts, scholars have reconstructed a prehistorical world and religion. The people who upheld this culture have been named, inter alia, "Indo-Europeans", "Aryans", "Japhetites" and "Wiros". Yet, these people have not left any texts, no artifacts can with certainty be ascribed to them, nor do we know any in
This thesis describes the design, synthesis and evaluation of synthetic inhibitors for the carbohydrate binding proteins called galectins. Potent and selective inhibitors can be used as important research tools in the endeavor to chart the true role of galectins in biological events such as cancer and inflammation and possibly as lead for future galectin targeting drugs. A panel of O-galactosyl a
The aim of this thesis was to analyze the value of pictures in a number of cognitive tasks that are predominantly verbal in nature. Three studies, with three experiments each, are included in the thesis. The first study found automatic interference effects from pictures (facial expressions) on the affective evaluation of words. In the Stroop-like presentation of integrated picture-and-word stimuli
The objective of this thesis is to develop a simulation tool and a method by which robot trajectories, temperature histories, residual stresses and distortion can be analysed and optimized off-line. This was performed by integrating robot simulation software with finite element analysis software. A special interface was created which facilitated information exchange between the two software progra
For people with central visual field loss, eccentric vision is all that they have to rely on. Even for those who learn how to correctly utilize their eccentric vision, it will never be as good as the central for two entirely different reasons: the off-axis optics of the eye can result in large refractive errors, and the low function of the peripheral retina. This thesis deals with the first of the
In this thesis a strategy perspective (the resource-based view) is applied to the New Technology-Based Firms (NTBFs) in Science Parks, arguing that the Science Park provides the firms with a set of resources that if used could help them build their resource base and thus develop and grow. Three categories of resources are identified in the Science Park; University related resources, Science Park f
Capsazepine and similar compounds, capsazepinoids, were shown to be general inhibitors of agonist (leukotriene D4, histamine, acetylcholine, prostaglandin D2) evoked constriction of human small airway preparations. The mechanism of action remains to be elucidated, but established bronchodilator principles, e.g. beta2-adrenoceptor agonism, as well as TRPV1 antagonism were shown to be less likely. F
This thesis presents the developement and verification of cutting force models for multi-toothed cutting processes. The scope of the thesis includes the modelling and measuring of factors that affect the mechanical load variation between individual cutting edges in the process. These factors will for example influence tool life and workpiece quality. The most important factors are; errors in radia
The aim of these studies has been to investigate what information that can be obtained on gel-emulsions with nuclear magnetic resonance, NMR, as the investigating tool. The gel-emulsions are important in many technical applications such as in food products, in cosmetic and pharmaceutical formulations, and in emulsion explosives, just to name a few applications. We have worked with the NMR diffusom
The rapid development of computer-based design analysis tools and methods such as the finite element method (FEM) within computational structural mechanics (CSM), computational fluid dynamics (CFD), and multi-body systems (MBS) during recent decades has fundamentally changed the way in which products are designed and developed. Among the many advantages observed in industrial practice, one can men
The development of immature progenitor cells into highly differentiated effector cells is a process central in modern medicine with applications in the fields of cell therapy as well as oncology. This thesis is focused on the molecular mechanisms that control the development of B lymphocytes. This is a complex and tightly regulated process involving several stages proceeding from stem cells to ant
Hydrophobic pervaporation has gained a lot of attention as an alternative process for mild aroma recovery, but the real commercial applications of this process are still in their infancies. Better understanding of mass transport phenomena in composite pervaporation membranes is essential from the point of view of membrane manufacturing, while process simulation is an important tool for predicting
This thesis aimed to investigate visual-vestibular interactions in healthy subjects and in patients with a well defined unilateral vestibular lesion (vestibular schwannoma before and six months after translabyrinthine surgery). Visual information is particularly important for balance control during perturbed stance. The physical act of having the eyes open or closed affects motion strategy in pos
The life and history of the Hawaiians has been documented ever since the contact with Western adventurers at the end of the 18th century. In connection with the arrival of American missionaries in 1820, these missionaries introduced and established a puritanical doctrine and method of communicating knowledge by way of the written word. The encounters between the different cultures have been descri
Obesity is increasing throughout the world at an epidemic rate, partly due to increased consumption of diets rich in fat and/or sugar. Ghrelin and leptin are hormones, originating from the periphery, involved in the regulation of food intake and of maintaining energy homeostasis. Circulating ghrelin levels increase in times of energy deficiency, such as fasting, signalling hunger whereas circulati
The present study is composed of eight chapters relating to children's rights and child labor activity in the Republic of Paraguay. The problem of child labor in Paraguay is central for this study and the legal ideals that are intended to uphold and strengthen the rights of the child are described and contrasted with the present normative reality in which the children work and live. The discrepanc
The ionization sensor is an electrical probe for diagnostics in internal combustion engines. The combustion process affects the electrical properties of the gas in the cylinder. Thus the sensor signal contains copious information about the conditions in the combustion chamber. A thorough characterization of the sensor makes it possible to take advantage of a larger portion of this information for
The sovereignty- and self-determination movements of indigenous peoples are a salient factor on the political agenda in many western world countries. Indigenous peoples in Hawai´i and elsewhere have become increasingly politicised in hope of changing their relationship with the states within which they are located. The discourse of indigenous peoples turn around the concept ”First Nations” whose c
There is an increasing need for education since the workforce of today is expected to be highly educated and continuously learn. Distance education is a powerful response to meet the growing need for education. Online education, here concisely defined as distance education mediated online, is the most common type of distance education. It mainly relies on asynchronous communication although it is
