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Hemicellulose isolation from thermomechanical pulp mill process water using UF: Optimisation and economics

Every year, 100,000 tons of dissolved hemicelluloses are discharge unused with wastewater from thermomechanical pulp mills around the world. Isolation of these hemicelluloses from the wastewater would not only reduce the treatment costs for the pulp mills but would also provide an excellent raw material for high value applications such as oxygen barriers in food packaging. The isolation of the hem

Assessment of cognition in ageing. Investigating internal validity, occurrence and reversion of Mild Cognitive Impairment. Data from the general population study “Good Aging in Skåne”

Bakgrund Med en snabbt växande äldre populationsgrupp kommer även andelen med kognitiva störningar, som demens, att växa. Det är således nödvändigt med forskning på kognition och åldrande. Denna avhandling, genom fyra delarbeten, redogör för testledareffekter vid kognitionsmätningar och hur yngre födelsekohorter (generationer) presterar bättre än äldre på kognitionstester. Den kommer även förklaraGiven a growing population of older adults and the common occurrence of natural as well as pathological cognitive decline, i.e. dementia, there is a need to better understand how to accurately measure and classify level of cognitive functioning. Both using multiple test administrators to collect cognitive data and what year the participant is born (birth cohort effects) can influence participants’

Apolipoprotein A-I in glucose metabolism and amyloidosis

The role of Apolipoprotein A-I (ApoA-I), the main protein component of HDL, in cholesterol transport and metabolism is well known and has been studied for more than four decades. More recently, ApoA-I protein has been shown to also have a positive role in glucose control by both stimulation of glucose uptake by muscles and by increasing glucose-stimulated pancreatic insulin secretion. Two of the f

Remote sensing of grassland communities : integrated effects of soil nutrients and habitat age

Semi-natural grasslands are characterized by high fine-scale plant species richness. The richest grassland communities, with many habitat-specialist species, are found in ancient grassland sites that have a long continuity of grazing management and low levels of soil nutrients. Grazed grasslands were widespread in the historical landscape. Agricultural intensification over the last two centuries h

Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease-Related β-Amyloid Status

Importance: Accurate blood-based biomarkers for Alzheimer disease (AD) might improve the diagnostic accuracy in primary care, referrals to memory clinics, and screenings for AD trials. Objective: To examine the accuracy of plasma β-amyloid (Aβ) and tau measured using fully automated assays together with other blood-based biomarkers to detect cerebral Aβ. Design, Setting, and Participants: Two pros

Modelling and Simulation of the Fifth-Generation District Heating and Cooling

Fjärrvärme och fjärrkyla är ändamålsenliga system för distribution av värme och kyla i tätbebyggda områden. Dessa system är viktiga vid planeringen av framtida energieffektiva system på grund av deras höga potential för att integrera förnybara energikällor. Systemen spelar också en viktig roll i samhällets energiförsörjningssäkerhet, vilket gör dem till ett tvärvetenskapligt forskningsområde. Den District heating and cooling are efficient systems for distributing heat and cold in urban areas. They are a key solution for planning future urban energy-efficient systems due to their high potential for integrating renewable energy sources. The systems also play an important role in community resilience, which makes them a multidisciplinary research topic. The continuous development of these sys

Low-level HIV viremia during antiretroviral therapy

In most cases, antiretroviral therapy (ART) results in undetectable plasma HIV viral load (VL). Still, up to 25% of ART recipients may have detectable low-level viremia (LLV) of different amplitude and persistence. This thesis explores the impact of LLV during ART on virologic and clinical outcomes. Paper I–III are retrospective analyses based on InfCare HIV, a national quality register for people

CUnT-SPLICING THOUGHT-FORMS : Promiscuous Play with Quantum Physics and Spirituality

CUnT-SPLICING THOUGHT-FORMS — Promiscuous Play with Quantum Physics and Spirituality could perhaps best be described as an invocation of excited states. In more ways than one, this dissertation indulges in a weird threesome between quantum thinking, tantric practices, and feminist theory, with artistic practice at its core. It proposes the term “cunt-splicing”—a reference to ropework and the so-ca

Land rent, capital, rate of profit : A critique of Harvey’s model of urban land rent

This study critically evaluates David Harvey’s model of urban land rent and its centrality in his explanation of the material forces that underlie and limit urban land policies, strategies, planning decisions, and investment choices. Harvey emphasizes structural forces of capital in relating economic urbanization processes to uneven patterns of capitalist development, recurrent economic crises of

The micrometeorite flux to Earth through the Phanerozoic Eon : Reconstructed using sediment-dispersed extraterrestrial spinels

The purpose of this thesis is to add an astronomical component to the history and evolution of Earth by reconstructing the micrometeorite flux to Earth at different time intervals during the Phanerozoic Eon, using sediment-dispersed extraterrestrial spinel group minerals as a proxy. Chromite and chrome spinel are common refractory members of the spinel group, occurring in both extraterrestrial and

Effect of Enteral Lipid Supplement on Severe Retinopathy of Prematurity : A Randomized Clinical Trial

Importance: Lack of arachidonic acid (AA) and docosahexaenoic acid (DHA) after extremely preterm birth may contribute to preterm morbidity, including retinopathy of prematurity (ROP).Objective: To determine whether enteral supplementation with fatty acids from birth to 40 weeks' postmenstrual age reduces ROP in extremely preterm infants.Design, Setting, and Participants: The Mega Donna Mega trial,

Characterisation of the genetic discordance between body mass index and type 2 diabetes: a phenome-wide analysis : No 111

Background and aims: Obesity is on the rise globally, and is a leading risk factor for T2D. However, it is very heterogeneous, with varying degrees of T2D risk within the same levels of BMI. Better classification may lead to improve outcomes of current preventive and therapeutic strategies. Moreover, by elucidating the mechanisms uncoupling obesity from T2D risk, new possible therapeutic targets m

Skiljeavtal, "tredje man" och step-in-klausuler – Särskilt om skiljebundenhetens omfattning och rättsliga grund

I svensk rätt gäller som huvudregel att ett avtal endast är bindande mellan parterna. Så är fallet även vad gäller skiljeavtal. Vissa typsituationer, till exempel singularsuccession och borgen, kan ge upphov till frågan om någon som inte skrivit under ett skiljeavtal (en icke-signatär) trots allt är skiljebunden. En följdfråga som uppstår är om icke-signatärens skiljebundenhet förutsätter att icke

Barn under straffbarhetsåldern i straffprocessen - En analys av bevistalans utvidgning i ljuset av barnkonventionens principer om barnets bästa i straffprocessen

Under senare år har en växande oro över att allt yngre barn misstänks för grov brottslighet drivit fram en kriminalpolitisk agenda och lagstiftningsreformer som successivt minskar skillnaderna mellan barn och vuxna i det svenska straffsystemet. År 2023 reformerades bevistaleinstitutet, genom vilket en domstol kan pröva om ett barn under 15 år har begått en brottslig gärning utan att någon påföljd

Vad bör en forensisk expert inte uttala sig om?

Mitt syfte med uppsatsen är att undersöka hur väl forensikers egen uppfattning om vad de bör uttala sig om och vad de inte bör uttala sig om stämmer överens med en idealbild av expertrollen. Mot bakgrund av syftet ställdes elva påståenden till 50 forensiska experter vid Nationellt forensiskt centrum (NFC) i form av en enkätundersökning. De sätt på vilka forensiker kan avvika från idealet som testa

Water Penetration in Solid Clay Brick Masonry and its Mitigation by Repointing

Clay brick masonry façades are widely used because of their extended durability and aesthetic appeal. They also offer good protection against wind-driven rain (WDR), one of the most common moisture sources in Northern Europe. In clay brick masonry, WDR is associated with elevated water content and the possibility of water penetration, which may negatively impact the hygrothermal performance of bui

Elevated carbohydrate antigen 125 (CA125) is associated with incident heart failure and mortality in acute coronary syndrome

AIMS: Carbohydrate antigen 125 (CA125), a mucin produced by serosal cells in response to mechanical and inflammatory stimuli, has emerged as an important biomarker to guide risk stratification in heart failure (HF). The prognostic value of CA125 in acute coronary syndrome (ACS) patients is less explored.METHODS: In a cohort of 524 ACS patients (73% males, mean age 67 ± 12 years), we assessed the a

Tau Positron Emission Tomography for Predicting Dementia in Individuals With Mild Cognitive Impairment

IMPORTANCE An accurate prognosis is especially pertinent in mild cognitive impairment (MCI), when individuals experience considerable uncertainty about future progression. OBJECTIVE To evaluate the prognostic value of tau positron emission tomography (PET) to predict clinical progression from MCI to dementia. DESIGN, SETTING, AND PARTICIPANTS This was a multicenter cohort study with external valid