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Natural organic matter (NOM) is found in all surface, ground, and soil waters. During recent decades, reports worldwide show a continuing increase in the color and NOM of the surface water, which has an adverse effect on drinking water purification. For several practical and hygienic reasons, the presence of NOM is undesirable in drinking water. Various technologies have been proposed for NOM remo
Aims/hypothesis: Growth differentiation factor 15 (GDF-15) is an anti-inflammatory cytokine of the transforming growth factor-β superfamily. Circulating levels of GDF-15 are associated with hyperglycaemia among people with obesity or diabetes, but longitudinal evidence on the association between GDF-15 levels and diabetes risk is scarce. Our aim was to explore whether circulating levels of GDF-15
Background: The duration of protection provided by varicella vaccines is unclear. We assessed the 10-year vaccine efficacy of two doses of a combined measles-mumps-rubella-varicella vaccine (MMRV), one live attenuated varicella vaccine (V) dose given after one measles-mumps-rubella vaccine (MMR) dose (MMR + V), versus two MMR doses (control vaccine) for the prevention of confirmed varicella. Metho
Background: Ovarian tumours are usually surgically removed because of the presumed risk of complications. Few large prospective studies on long-term follow-up of adnexal masses exist. We aimed to estimate the cumulative incidence of cyst complications and malignancy during the first 2 years of follow-up after adnexal masses have been classified as benign by use of ultrasonography. Methods: In the
Background: Seasonal variation in glucose metabolism might be driven by changes in daylight. Melatonin entrains circadian regulation and is directly associated with daylight. The relationship between melatonin receptor 1B gene variants with glycemic traits and type 2 diabetes is well established. We studied if daylight length was associated with glycemic traits and if it modified the relationship
Lung cancer is a common cancer type associated with poor prognosis. Even in the group of patients with earlystage tumors, for which curative treatment is possible, lung cancer recurrence is frequent. The aim of this thesis was to investigate the potential prognostic role of mutations in tumor specimens, blood-based proteins and circulating tumor DNA.In study I, we performed EGFR mutation detection
Heart failure (HF) is a morbid and heritable disorder for which the biological mechanisms are incompletely understood. We therefore examined genetic associations with HF in a large national biobank, and assessed whether refined phenotypic classification would facilitate genetic discovery. Methods: We defined all-cause HF among 488 010 parti
Objective: To investigate the causal role of cardiometabolic risk factors in osteoarthritis (OA) using associated genetic variants. Methods: We studied 27,691 adults from the Malmö Diet and Cancer Study (MDCS) and replicated novel findings among 376,435 adults from the UK Biobank. Trait-specific polygenic risk scores for low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol
Bergskedjor är uppbyggda av olika slags berggrund som skjutits samman i de zoner på Jorden där tektoniska plattor möts (konvergerar). Sådana processer sker i dag exempelvis i Himalaya, Alperna eller Anderna, men det finns också gamla, nu inaktiva, bergskedjor som de Skandinaviska Kaledoniderna (ca 400 miljoner år gammal) eller den Svekonorvegiska bergskedjan (ca 1000 miljoner år gammal, i sydvästr
Background We recently reported a relationship between plasma levels of cystatin C and incidence of the metabolic syndrome (MetS) among the first 2,369 subjects who participated in the reexamination study of the population-based Malmö and Diet Cancer Cardiovascular cohort (MDC-CC-re-exam). In this study we aimed to replicate these results and also investigate if cystatin C was causally associated
Politisk komedi är en hybridgenre där politiska nyheter och analyser blandas med komedi och underhållning. Allt eftersom politisk komedi ökar i popularitet – i de flesta medieformer och nationella kontexter – arbetar forskare med att förstå dess roll i relation till medborgarskap, och det kan konstateras att genren utmanar den vetenskapliga förståelsen av politiska medier och medborgarskap. Denna Political comedy is a hybrid genre that mixes political news and analysis with comedy and entertainment. As it becomes more and more popular in most media forms and national contexts, researchers struggle to understand its role in relation to other types of political media, and of citizenship; in this sense, it challenges scholarly conceptualisation of political media and citizenship. Thus, this t
The rugged field and group of trees between housing estates or next to the railroad tracks, the left-over space of deserted industrial areas, the vacant demolition site of a central city block – they could all be termed ‘urban voids’. However, they are often anything but voids, in a literal sense, as they are not empty, or deserted. Yet they are ‘urban voids’, lacking an evident function, or a
Importance: The role of ω-3 polyunsaturated fatty acids for primary prevention of coronary heart disease (CHD) remains controversial. Most prior longitudinal studies evaluated self-reported consumption rather than biomarkers. Objective: To evaluate biomarkers of seafood-derived eicosapentaenoic acid (EPA; 20:5 ω-3), docosapentaenoic acid (DPA; 22:5 ω-3), and docosahexaenoic acid (DHA; 22:6 ω-3) an
Vi har lyckan att leva i en föränderlig värld, och med förändringar följer variation. Den stora variationen i yttre egenskaper hos djur, och i synnerhet deras färger, fascinerar både forskare och lekmän. I den här avhandlingen utforskar jag flera aspekter på varför, och hur, färgvariation evolverar hos en karismatisk insektsgrupp. Dammflicksländor är färgglada, dagaktiva och visuellt drivna organiSexual conflict over mating shapes the interactions between males and females in many animals and is also responsible for dramatic adaptations in both sexes. In some species of pond damselflies (Odonata:Coeangrionidae), sexual conflict maintains discrete female-limited colour morphs over multiple generations and within populations. One of the female morphs is typically male-coloured and considered
INDEPENDENCE DAY is a furious and poetic performance that dissolves, destroys and liberates the theatre and the music, the chronology and the linear narratives, letting the world unfold by carefully cutting it apart without putting it together again. October 9, 2002: Aileen Wuornos’s last words before her execution: I'd just like to say I'm sailing with the Rock, and I'll be back like Independence
Importance: Low academic achievement (AA) in childhood and adolescence is associated with increased substance use. Empirical evidence, using longitudinal epidemiologic data, may provide support for interventions to improve AA as a means to reduce risk of drug abuse (DA). Objective: To clarify the nature of the association between adolescent AA and risk of DA by using instrumental variable and co-r
Background: Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British Food St
BACKGROUND: Incidental durotomy (ID) is one of the most common intraoperative complications seen in spine surgery. Conflicting evidence has been presented regarding whether or not outcomes are affected by the presence of an ID. PURPOSE: To evaluate whether outcomes following degenerative spine surgery are affected by ID and the incidence of ID with different diagnoses and different surgical proced
