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Background: White adipose tissue (WAT) dysfunction including an aberrant expression of miRNAs is strongly associated with the risk of developing type 2 diabetes (T2D), with limited evidence linking early changes in the WAT-derived miRNAs and T2D. The present study aims to identify early miRNome changes prognostic for T2D in mice and humans. Methods: Gonadal (g) WAT of diabetes-resistant and diabet
BACKGROUND Surgical site infection (SSI) following orthopedic surgery impacts patient outcomes. Airborne transmission is one potential route of infection. Despite their high cost and resource demands, modern ventilation systems have shown limited efficacy in reducing SSI rates. This trial investigated the effectiveness of a low-cost air purifier in reducing SSI rates after orthopedic surgery. METH
Rapidly evolving academic and professional environments require essential skills such as communication, collaboration, creativity and critical thinking, which are not typically learned and assessed explicitly in formal education. These skills encompass a significant part of the competencies and are increasingly valued in an AI-driven workforce because they cannot be easily replicated by machines.
Background: Midwifery continuity of care (MCoC) is a key aspect of woman-centred midwifery care, associated with improved outcomes for both women and midwives. In many countries, maternity care is fragmented, and MCoC uncommon in clinical practice and midwifery education. To address this gap, a pedagogical project entitled “Midwifery Student All the Way” was introduced in a midwifery programme in
Digital transformation of healthcare has largely been conceptualised throughadoption-centric lenses, relying on “barriers and facilitators” frameworks thatfocus primarily on individual technology adoption or organisational factors.Yet transformation in practice depends on sustained coordination amongmultiple autonomous actors who must align their actions across organisational,professional, and tec
Background/objectives: Glucose-dependent insulinotropic polypeptide (GIP) is secreted by enteroendocrine K cells in response to nutrient ingestion. The aims of this study were: i) to evaluate the cross-sectional associations between plasma GIP change in response to an oral glucose challenge (as a surrogate of GIP secretion) with obesity-related anthropometric measurements, fasting inflammatory bio
Background: The prognostic benefit of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) in stable coronary artery disease (CAD) remains uncertain. Objectives: To evaluate long-term survival following CTO PCI compared with medical therapy (MT) using target trial emulation and a nationwide real-world registry. Methods: We included 7813 patients with stable CAD and a document
Purpose: – We sought to develop an equation, the Alma College Estimation (ACE) equation, to estimate survival equivalent to the Duke treadmill score (DTS) and Duke nomogram. Methods: – Combinations of ST segment deviation (0, 1, 2, 3, and 4 mm), angina (0 = none, 1 = nonlimiting, and 2 = limiting), and metabolic equivalents of task (2–20) were graphed on the Duke nomogram, and the ACE equation was
D-dimer has been proven to be an excellent rule-out marker for acute type A aortic dissection (ATAAD) with a sensitivity exceeding 95% while specificity remains low. We hypothesized that the addition of fibrinogen, which is decreased in ATAAD patients due to consumption coagulopathy, would increase predictive ability. This was an exploratory, retrospective, single-region, observational study compa
Objective: Prior to in vitro fertilization (IVF), physicians can choose either recombinant or urine-derived follicle-stimulating hormone (FSH) for ovarian stimulation. The common polymorphism N680S (rs6166) in the follicle-stimulating hormone receptor (FSHR) has been linked to individual variability in ovarian response to FSH stimulation and IVF outcomes, including live birth rates, highlighting i
Eutrophication, caused by excessive accumulation of key nutrients such as nitrogen and phosphorus in water, is a major environmental problem that significantly affects water quality and aquatic ecosystems. This thesis project aims to evaluate different adsorption-based treatment methods that can effectively reduce the nutrient content of water. Water samples were collected from various water sourc
Most cutaneous malignant melanomas (CMMs) are thin (≤1.0 mm, stage T1) with an expected 10-year melanoma-specific survival of 93%–97%. The incidence of CMM is higher in groups with high socioeconomic status (SES). We aimed to assess overall survival (OS) and detailed characteristics in individuals with thin CMM as compared to the general population matched on age, sex, and county of residence. Mat
PURPOSE: Provision of adequate support is much needed to secure equal educational opportunities for students with developmental language disorder (DLD). Important perspectives on support provision and its impact on academic progress are held by school professionals, caregivers, and students with DLD. This study sought to further the current knowledge on the perceived relation between educational s
Mental imagery allows us to simulate events and experiences and plays a crucial role in language comprehension. Vividness, defined as the subjective richness and clarity of these simulations, varies across individuals and contexts. Whether mental imagery vividness decreases when processing in a non-native (L2) compared to a native (L1) language remains debated (Montero-Melis et al., 2020). Reducti
Maskin- och monteringshallen i Varvsstaden i Malmö är en del av det tidigare Kockums-området, som under 1900-talet var en av stadens viktigaste industrimiljöer. Här byggdes fartyg som exporterades över hela världen, och området kom att spela en central roll i Malmös industriella utveckling. Hallen uppfördes 1912 och är idag ett kulturhistoriskt värdefullt industriminne som bevaras inom ramen för o
PurposeStreptococcus pyogenes is a cause of endometritis, a severe infection in women of reproductive age. S. pyogenes is classified into emm-types based on variations of the emm-gene. We aimed to compare the distribution of emm-types in endometritis to that of controls with bacteraemia, and to assess associations between emm-types and disease severity or clustering of cases.MethodsVaginal or cerv
