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Clinical trials examining insulin-like growth factor-I receptor (IGF1R)-targeting strategies have emphasized that better predictive biomarkers are required to improve patient selection. Immunohistochemical tumor-specific protein expression of IGF1R, insulin receptor (InsR), and phosphorylated IGF1R/InsR (pIGF1R/InsR) individually and combined in relation to breast cancer prognosis was evaluated in
Background and Objectives: The T-cell response to low-density lipoprotein (LDL) in the vessel wall plays a critical role in atherosclerotic plaque formation and stability. In this study, we used a new translational approach to investigate epitopes from human apolipoprotein B100 (ApoB100), the protein component of LDL, which triggers T-cell activation. We also evaluated the potential of two selecte
Gastric bypass surgery results in remission of type 2 diabetes in the majority of patients. The incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) have been implicated in the observed remission. Most knowledge so far has been generated in obese subjects. To isolate the surgical effects of gastric bypass on metabolism and hormone responses from
The performance of truck drivers is crucial to the sustainability, in particular profitability, of motor carrier operations. Despite this, driver efficiency has received scarce attention in the transport and logistics literature. While the literature has focused on mathematical optimization, generic logistics frameworks and conceptual technology applications, measurement of drivers’ efficiency has
Background: Observational studies implicate higher dietary energy density (DED) as a potential risk factor for weight gain and obesity. It has been hypothesized that DED may also be associated with risk of type 2 diabetes (T2D), but limited evidence exists. Therefore, we investigated the association between DED and risk of T2D in a large prospective study with heterogeneity of dietary intake. Meth
Objective: To describe dietary carbohydrate intakes and their food sources among 27 centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods: Between 1995 and 2000, 36 034 subjects, aged between 35-74 years, were administered a standardized, 24-h dietary recall using a computerized interview software programme (EPIC-SOFT). Inta
It is generally recognised that agricultural intensification has lead to simplification of landscape structure, but it has not been clarified if this is a ubiquitous relationship. That is, it has been an open question whether agricultural intensity and landscape simplicity should be regarded as one single or as two separate dimensions. To evaluate this we analysed landscape data in 136 different 1
Background--Atherosclerosis is an inflammatory lipid disorder and the main underlying pathology of acute ischemic events. Despite a vast amount of data from murine atherosclerosis models, evidence of B-cell involvement in human atherosclerotic disease is limited. We therefore investigated the association of circulating B-cell subtypes with the occurrence of secondary cardiovascular events in advan
This master thesis has its setting in the theoretical field of archaeology. The aim is to identify if there are conventional traditions in the archaeological research based on specific periods and if there are, investigate the differences and similarities. The thesis takes inspiration from the well known sociologist Pierre Bourdieu and what he says about the objective structures in society; struct
Rening av avloppsvatten – Nya lösningar och möjligheter Findus Sverige AB i Bjuv strax utanför Helsingborg är en av norra Europas största producenter av frysta grönsaker. De processer som produktionen innebär är extremt vattenkrävande och ger upphov till stora mängder processvatten. Företaget har ett eget reningsverk som används för att rena processvattnet innan det släpps ut till recipienten Veg
Parasitter og cytokiner i en naturlig populasjon I naturen finner vi utallige eksempler på arter som har spesialisert seg på å utnytte andre arter for næring, trygghet og overlevelse. Denne spesialiseringen kalles parasitisme, og har ofte en kostnad for verten i form av redusert helse og livskvalitet. Hos däggdjur, er en stor parasittgruppe innvollsparasitter. nematoder som lever i tarmene og sugAbstract In nature, the coexistence of parasites and hosts has been an important factor in evolution of the immune system, which can be found in all plants and animals. As parasitic infections are by definition affect overall fitness of the host, it is important for the host to be able to counteract the detrimental effects of infections. To ensure this, signaling molecules, known as cytokines, e
Molecular cluster is a nanoparticle that is defined as an agglomerate of few up to 106-7 of molecules (corresponding to 1- 100 nm in size) that can be manipulated by the cluster beams. Molecular cluster properties typically lie between the individual molecule and bulk matter properties. This work describes the employment of the Cold Aerodynamic Source (CAS) to produce a narrow, collimated and iso
Title: The implementation of IFRS and the effects on dividends. Seminar date: 2013-05-30 Course: BUSN69.Degree project-Accounting and auditing, 15 ECTS credits Authors: Henrik Alwén and Johan Rybäck. Supervisor: Kristina Artsberg. Key words: Divided policy, earnings, fair value, gross profit, IFRS. Purpose: The purpose with this thesis is to analyze whether the implementation of IFRS have impacte
I svensk rätt har den som erlagt betalning av misstag som huvudregel, enligt principen om condictio indebiti, rätt att få pengarna åter. Huvudregeln motiveras av det faktum att mottagaren inte har någon rätt till de erhållna medlen och därmed inte heller något beaktansvärt intresse av att få behålla dem. Det finns emellertid fall då omständigheterna vid betalningen och händelseförloppet därefter g
The subject of our master’s thesis is museum exhibitions for children. The thesis is based on three research questions: “What purposes do institutions have when they decide to produce museum exhibitions specifically for children?”, “What are the similarities and differences concerning the intermediation techniques, voice and intent in this type of exhibitions?” and “How does the underlying intenti
