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Background: In order to diagnose children with ADHD, the DSM-IV measures inattention (IA) and hyperactivity/impulsivity (HI) behavior in the context of significant impairment social and academic function. In order to diagnose, symptoms must be present in two different setting, which is commonly established in terms of home and school behaviors with the help of parent and teacher reports. Previous

Sammanfattning: Examensarbetet ingår som det sista momentet på geovetarlinjens fjärde år vid Lunds universitet. Det har utförts vid Studsvik Energiteknik AB inom affärsområdet Säkerhetoch systemanalys vid NPE-gruppen. Studsvik är beläget ca 25 km nordost om Nyköping och ca 90 km söder om Stockholm. Examensarbetet har utgjort en del av ett forsknings- och utvecklingsprojekt, kallat "Recipient

I avtal som ingås mellan kommersiella parter är det idag vanligt att skiljeförfarande väljs som tvistlösningsmetod. Det framhålls särskilt att det är en tvistlösningsmetod som bidrar till ett snabbt avgörande, ger parterna rätten att själva utse skiljemän samt att det är ett förfarande präglat av konfidentiellitet. Samtidigt brukar de kostnader som är förenade med skiljeförfarandet framhållas som Today, when commercial parties are contracting, it is common that they choose arbitration as their method of dispute resolution. In contrast to court proceedings, arbitration gives a quicker judgement, gives the parties the right to elect their arbitrators and is a process that is characterized by confidentiality. On the other hand, arbitration also comes with some disadvantages. One example, whic

HLA-DQA1 and -DQB1 genes have significant and potentially causal associations with autoimmune type 1 diabetes (T1D). To follow on the earlier analysis on high-risk HLA-DQ2.5 and DQ8.1, the current analysis uncovers seven residues (αa1, α157, α196, β9, β30, β57, β70) that are resistant to T1D among subjects with DQ4, 5, 6 and 7 resistant DQ haplotypes. These seven residues form 13 common motifs; si

BACKGROUND: Although the impact of pancreatic infections in acute pancreatitis has been studied extensively, there are no population-based data on extrapancreatic infections and their potential relation to organ failure. We aimed to study the occurrence of pancreatic and extrapancreatic bacterial infections in acute pancreatitis and their relation to patient outcome. PATIENTS AND METHODS: All pati

Soil contamination is a widespread problem and actions need to be taken in order toprevent damage to the groundwater and the life around the contaminated sites. InSweden more than 80.000 sites are potentially contaminated, therefore there is ademand for accurate and efficient methods for site characterization and soilremediation. In the past, the preferred methodology for soil remediation involved

Denna avhandling studerar lokala aktörers roll vid förändringsarbete i gamla industriregioner. En gammal industriregion definieras som ett område med en ensidig och överspecialiserad industristruktur, som är dominerad av mogen industri och som upplever minskad sysselsättning och/eller avindustrialisering. Denna typ av region är ofta starkt påverkad av gamla strukturer och förväntas därför ha svåraThe aim of the dissertation is to develop a better understanding of the role of local agency in the transformation of old industrial regions. Theoretically the dissertation builds on concepts which are important in the debate on regional development in old industrial regions such as path dependency, negative lock-ins, the role of institutions, and new path development, while exploring and unpackin

Industrial symbiosis can move us closer to a circular economy and enable efficient and sustainable use of resources. Its potential has however been far from realized, and to increase our understanding of why that is, we investigate drivers, barriers, and outcomes associated with both broadly defined environmental sustainability initiatives and industrial symbiosis from an organizational context pe

OBJECTIVES: Very early-life conditions are recognized as critical for healthy brain development. This study assesses early-life risk factors for developing dementia. In the absence of historical medical birth records, we leverage an alternative full population approach using demographic characteristics obtained from administrative data to derive proxy indicators for birth complications and unfavor

Alzheimer's disease is a neurodegenerative condition which involves heavy neuronal cell death linked to oligomers formed during the aggregation process of the amyloid β peptide 42 (Aβ42). The aggregation of Aβ42 involves both primary and secondary nucleation. Secondary nucleation dominates the generation of oligomers and involves the formation of new aggregates from monomers on catalytic fibril su

OBJECTIVE: To distinguish among predictors of seroconversion, progression to multiple autoantibodies and from multiple autoantibodies to type 1 diabetes in young children.RESEARCH DESIGN AND METHODS: Genetically high-risk newborns (n = 8,502) were followed for a median of 11.2 years (interquartile range 9.3-12.6); 835 (9.8%) developed islet autoantibodies and 283 (3.3%) were diagnosed with type 1

Background: Skeletal muscle fiber type distribution has implications for human health, muscle function, and performance. This knowledge has been gathered using labor-intensive and costly methodology that limited these studies. Here, we present a method based on muscle tissue RNA sequencing data (totRNAseq) to estimate the distribution of skeletal muscle fiber types from frozen human samples, allow

Differentiation of smooth muscle cells (SMCs) depends on serum response factor (SRF) and its co-activator myocardin (MYOCD). The role of MYOCD for the SMC program of gene transcription is well established. In contrast, the role of MYOCD in control of SMC-specific alternative exon usage, including exon splicing, has not been explored. In the current work we identified four splicing factors (MBNL1,