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Crowdability of Urban Space. : Ordinary rhythms of clustering and declustering and their architectural prerequisites

In the wake of densification and urbanisation, crowding has become an increasingly important issue for social sustainability in cities. This also affects urban design and the ways public spaces stimulate different kinds of crowding and clustering. There are, of course, several factors which affect pedestrian clustering and declustering in public spaces, factors that determine how and why people ac

A hypothesis for insulin resistance in primary human adipocytes involving MRTF-A and suppression of PPARγ

Obesity is the main risk factor behind insulin resistance and type 2 diabetes. Still, the mechanism behind adipocyte dysfunction is not yet resolved. Recently, we reported that rapid actin remodeling correlates with adipose cell size changes after short-term overfeeding. Therefore, we hypothesized that the actin-driven myocardin-related transcription factor (MRTF-A) contributes to impaired mature

Paradoxes of Media and Information Literacy : The Crisis of Information

Paradoxes of Media and Information Literacy: The Crisis of Information contributes to ongoing conversations about control of knowledge and different ways of knowing. It does so by analysing how media and information literacy (MIL) is proposed as a solution for addressing society’s crisis of information. Questioning why MIL is commonly believed to wield such power, the book throws into sharp relief

Creative organizational climate – testing Ekvall’s 10-dimension model

To measure organizational climate for creativity and innovation Ekvall’s 10-dimension model is widely used both in research and in practice. The model consists of the 10 dimensions; challenge, freedom, idea support, trust, dynamism, playfulness, debate, conflicts risk-taking, and idea time. Outgoing from these dimensions Ekvall (1996) developed the Creative Climate Questionnaire (CCQ), shown to di

Joys of Mobility in the On-line game World of Warcraft : “I like my Horse, but I Loove my Flying Mount!”

It is today commonplace that games and virtual worlds are not only multi-billion dollar businesses but also momentous socio-cultural phenomena that require critical attention. Massively Multiplayer On-line Games (MMOGs) are these days becoming recognized not only as grounds for play within ‘magic circles’ but also as complex and significant social spaces with 24-7 access to the millions of gamers

The water-supply system in Roman Pompeii

This study focusses on the urban infrastructure for water supply in Roman Pompeii. The water distribution network of lead pipes was constructed inside the city walls, at the time when the city was connected to an aqueduct. Life for the Pompeiians changed considerably when aqueduct water started running continuously in street fountains all around the city. The study is based on previous research an

Risk factors for unnatural death : Fatal accidental intoxication, undetermined intent and suicide: Register follow-up in a criminal justice population with substance use problems

BACKGROUND: Risk factors for suicide and fatal accidental intoxication are extensively studied, while risk factors for intoxications/injuries of undetermined intent are less well known. The latter have shown an overlap with suicides, but also with fatal accidental intoxications. The objective was to analyze potential differences and similarities in the patterns of risk factors for accidental intox

User value and usability of a web-based mindfulness intervention for families living with mental health problems

Mental health problems affect the patients and their families, who may also need therapeutic interventions. Mindfulness interventions have shown beneficial health effects for clinical and healthy populations. A web-based mindfulness intervention was tailored to address families' needs of support and tested in a pilot intervention study. The aim of this study was to explore the participants' experi

Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes

Aims/hypothesis: Genome-wide association studies (GWAS) have identified more than 65 genetic loci associated with risk of type 2 diabetes. However, the contribution of distorted parental transmission of alleles to risk of type 2 diabetes has been mostly unexplored. Our goal was therefore to search for parent-of-origin effects (POE) among type 2 diabetes loci in families. Methods: Families from the

General practice in the Nordic countries

Background: General practice systems in the Nordic countries share certain common features. The sector is based on the Nordic model of a tax-financed supply of services with a political objective of equal access for all. The countries also share the challenges of increased political expectations to deliver primary prevention and increased workload as patients from hospital care are discharged earl

Operationalizing Ecosystem-Based Adaptation: Harnessing Ecosystem Services to Buffer Communities against Climate Change

Ecosystem-based approaches for climate change adaptation are promoted at international, national, and local levels by both scholars and practitioners. However, local planning practices that support these approaches are scattered, and measures are neither systematically implemented nor comprehensively reviewed. Against this background, this paper advances the operationalization of ecosystem-based a

Genome wide association study identifies two loci associated with cadmium in erythrocytes among never-smokers

BACKGROUND: Cadmium is a non-essential toxic metal with multiple adverse health effects. Exposure in the general population occurs by smoking and diet. Cadmium in erythrocytes is a valid biomarker of exposure and body burden of cadmium.OBJECTIVES: We aimed to identify genetic variants related to concentrations of cadmium in erythrocytes.METHODS: Erythrocyte cadmium was analyzed in 4432 individuals