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Alcohol consumption and risk of urothelial cell bladder cancer in the European prospective investigation into cancer and nutrition cohort

Findings on the association between alcohol consumption and bladder cancer are inconsistent. We investigated that association in the European Prospective Investigation into Cancer and Nutrition cohort. We included 476,160 individuals mostly aged 35–70 years, enrolled in ten countries and followed for 13.9 years on average. Hazard ratios (HR) for developing urothelial cell carcinoma (UCC; 1,802 inc

Loneliness, health and mortality

Aims.: Literature suggests an association between loneliness and mortality for both males and females. Yet, the linkage of loneliness to mortality is not thoroughly examined, and need to be replicated with a long follow-up time. This study assessed the association between loneliness and mortality, including associations to gender, in 1363 adult swedes. Methods.: This community-based prospective co

Analysis of fire barriers with respect to fires with combustible gases and liquids

Fires including flammable gases and/or liquids differ from typical residential fires where the fuel is mainly composed of solid combustibles. The traditional ISO 834 curve was established to represent the timetemperature curve for a fully developed fire. However for combustible gases the type of thermal exposure might be substantially different and therefore other curves have been developed such a

Glucagon-like peptide-1 and glucose-dependent insulinotropic peptide : effects alone and in combination on insulin secretion and glucose disappearance in mice

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) stimulate insulin secretion. They are both released after meal ingestion, and therefore they might cooperate in their actions. However, whether there is a cooperative action of the two incretins is not known. This study therefore investigated the effects on insulin secretion and glucose disappearance of GLP-1 and GI

No independent association between pulse wave velocity and dementia : a population-based, prospective study

OBJECTIVE:: Carotid–femoral pulse wave velocity (CFPWV), a marker of aortic stiffness, has been associated with cognitive test results and markers of cerebral small vessel disease, but its association with dementia has not been studied in detail. Our aim was to assess the association of CFPWV with prevalent and incident dementia in a large population-based study. METHODS:: In total, CFPWV was meas

Discussing the Thesis Writing : How do doctoral students and supervisors communicate?

Effective communication between students and supervisors has been shown to be of importance for a high quality doctoral education by many pedagogical studies (Manathunga [1], Delamont, Aktinson and Parry [2], Halse and Malfroy [3], Bergnéher [4]). This contribution focuses on communication between supervisors and doctoral students with regard to the writing of the doctoral thesis. When it comes toEffective communication between students and supervisors has been shown to be of importance for a high quality doctoral education by many pedagogical studies (Manathunga [1], Delamont, Aktinson and Parry [2], Halse and Malfroy [3], Bergnéher [4]). This contribution focuses on communication between supervisors and doctoral students with regard to the writing of the doctoral thesis. When it comes to

Association between statin use and consultation or surgery for osteoarthritis of the hip or knee : A pooled analysis of four cohort studies

Objective: Experimental findings and previous observational data have suggested lower risk of osteoarthritis (OA) with statin use but results are inconsistent. Large-scale studies with a clinically important outcome are needed. Thus, we aimed to determine whether statin use is associated with a reduced risk of developing clinically-defined hip or knee OA. Design: Pooled analysis based on time-to-e

Metformin treatment significantly enhances intestinal glucose uptake in patients with type 2 diabetes : Results from a randomized clinical trial

Aims Metformin therapy is associated with diffuse intestinal 18F-fluoro-deoxyglucose (FDG) accumulation in clinical diagnostics using routine FDG-PET imaging. We aimed to study whether metformin induced glucose uptake in intestine is associated with the improved glycaemic control in patients with type 2 diabetes. Therefore, we compared the effects of metformin and rosiglitazone on intestinal gluco

Substantial decline of Northern European peatland bird populations : Consequences of drainage

Northern European peatlands are important habitats for biological conservation because they support rich biodiversity and unique species compositions. However, historical management of peatland habitats has had negative consequences for biodiversity and their degradation remains a major conservation concern. Despite increasing awareness of the conservation value of peatlands, the statuses and ecol

Den självorganiserade staden: appropriation av offentliga rum i Rinkeby

The objective of this dissertation is to analyse and discuss the issue of self-organisation from a spatial point of view. The thesis takes its point of departure firstly from the assumption that self-organisation concerns a process through which subjects aspire to become involved in societal development and decision-making from below, and secondly that self-organisation always takes place in a soc

Breast-feeding, nasopharyngeal colonization and otitis media.

This thesis analyzed the relationship between breastfeeding, nasopharyngeal colonization and acute otitis media (AOM) in children. Nasopharyngeal cultures were collected from 400 children and milk samples from their mothers in connection with the scheduled visits to well baby clinics at 1-3, 4-7 and 8-12 months of age, and episodes of AOM and URI were documented. The nasopharyngeal flora was acqui

Creative organizational climate – testing Ekvall’s 10-dimension model

To measure organizational climate for creativity and innovation Ekvall’s 10-dimension model is widely used both in research and in practice. The model consists of the 10 dimensions; challenge, freedom, idea support, trust, dynamism, playfulness, debate, conflicts risk-taking, and idea time. Outgoing from these dimensions Ekvall (1996) developed the Creative Climate Questionnaire (CCQ), shown to di

The integration of customer needs in e-business systems

The establishment of e-businesses has often been implemented from the inside of companies rather than from the customer perspective and the knowledge about customer needs from traditional businesses have been applied directly into new e-business systems. The overall objective of this study is to identify how to better understand customer needs and how to integrate these needs in order to create cu

This Time It’s Personal: Social Networks, Viral Politics and Identity Management

This chapter deals with political mobilisation and participation in social media. The main focus is on the impor¬tance of Internet-mediated social networks in providing a “media filter”, functioning as a kind of collective gatekeeper to spread news and information perceived as important, in contrast to the image of the single individual media consumer faced with an in¬surmount¬able mass of informa

The functional variant V433M of the CYP4F2 and the metabolic syndrome in Swedes.

BACKGROUND AND AIM: The genetic basis of Metabolic syndrome (MetS) is largely unknown but a link with salt sensitivity is recognized. The cytochrome P450 isoform 4F2 (CYP4F2) is involved in renal production of 20-hydroxyeicosatethraenoic acid (20-HETE), a natriuretic substance associated with salt sensitivity. The same enzyme is implicated in ω-hydroxylation of very long and medium chain fatty aci

Dietary intake of total polyphenol and polyphenol classes and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Polyphenols may play a chemopreventive role in colorectal cancer (CRC); however, epidemiological evidence supporting a role for intake of individual polyphenol classes, other than flavonoids is insufficient. We evaluated the association between dietary intakes of total and individual classes and subclasses of polyphenols and CRC risk and its main subsites, colon and rectum, within the European Pro

Familial aggregation and heterogeneity of non-Hodgkin lymphoma in population-based samples

The importance of genetic factors in the etiology of non-Hodgkin lymphoma (NHL) is suggested by case-control and cohort studies. Most previous studies have been too small to estimate accurately risks of specific categories of lymphoproliferative malignancies in relatives of NHL cases or to quantify the contribution of NHL case characteristics to familial risk. We have overcome sample size limitati