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Fibrillin-1 (FBN1) is an important constituent of the vascular wall and earlier studies have indicated an effect of the FBN1 2/3 genotype on blood pressure as well as aortic stiffness in men. The aim of the present study was to determine whether the FBN1 2/3 genotype was associated with the presence of carotid plaque and incident cardiovascular morbidity and mortality in middle-aged subjects. The
Grey scale median (GSM) measured on ultrasound images of carotid plaques has been used for several years now in research to find the vulnerable plaque. Centres have used different software and also different methods for GSM measurement. This has resulted in a wide range of GSM values and cut-off values for the detection of the vulnerable plaque. The aim of this study was to compare the values obta
Coronary heart disease (CHD) is an archetypical multifactorial disorder that is influenced by genetic susceptibility as well as both modifiable and nonmodifiable risk factors, and their interactions. Advances during recent years in the field of multifactorial genetics, in particular genomewide association studies (GWASs) and their meta-analyses, have provided the statistical power to identify and
Background: The Patient-Reported Indices for Multiple Sclerosis (PRIMUS) comprises a suite of three scales for assessing symptoms, activity limitations, and quality of life in multiple sclerosis (MS). It was developed in the UK and has been shown to have excellent psychometric properties. This study describes the adaptation of eight language versions for Canadian English, Canadian French, French,
Genetics, epigenetics and environment may together affect the susceptibility for type 2 diabetes (T2D). Our aim was to dissect molecular mechanisms underlying T2D using genome-wide expression and DNA methylation data in adipose tissue from monozygotic twin pairs discordant for T2D and independent case-control cohorts. In adipose tissue from discordant twins, we found decreased expression of genes
Objective. To study the clinical recovery from acute otitis media ( AOM) in children, 2-16 years of age, managed with or without treatment with phenoxymethylpenicillin ( PcV). Design. An open, prospective randomized trial. Children aged between 2 and 16 years, presenting with one- or double-sided AOM ( without perforation) with symptom duration of less than four days, were included. The children w
Nanoteknik är ‘big business’. Stora summor pengar står på spel då detta innovativa teknikområde expanderar i snabb takt. Denna undersökning utgår från antagandet att ekonomiska intressen snarare än demokratiska värden och hållbar utveckling styr utvecklingen av nanoteknik i Sverige idag. Detta ses som problematiskt, och det övergripande målet är att föreslå alternativa principer för att styra utve
Title: Identifying with fun and family in the time of changes and downsize. Seminar date: June 1st, 2009 Course: Masters thesis in Business Administration Programme for Managing People, Knowledge and Change, 15 University Credit Points (15 ECTS). Author: Ellert Örn Erlingsson and Elvar Ólafsson Advisor: Sara Louise Muhr Key words: Cultural family metaphor, Resistance, Cynicism, Organizational iden
This study challenges existing dogma of economists and environmentalists with a finding that sustainable consumption in industrial societies is impossible within standard models of growth because the approaches that are being taken to investments (in new technologies) are linked with and dependent on increased consumption as a requirement of innovation and as part of ideology in societies. Though
"What should we have for dinner?" is one of the most challenging and anxiety provoking questions of today. In a society where appreciation for eating rituals and common knowledge about food have been almost lost, a new look at layout, space and functions of kitchens is needed to demystify and dedramatize the dogmatic image people have of cooking so they can rediscover the fun in the kitc
The bachelor thesis was to create a GPS tracking system for Svep Design Center AB. The system would consist of two major parts which were linked together through a common database. One part consisted of a cell phone application were the user can transmit their current position and the other part was a web application where the position data is presented on a map outlining the route of the user. Si
Bankerna innehar en stark ställning i vårt finansiella system och både privatpersoner och samhället i stort är beroende av att de fungerar och är stabila. Vad som börjar som en kris hos en bank sprider sig lätt till andra och riskerar att utmynna i en finanskris. När nu banker är så viktiga i vårt samhälle, vilken syn på bankers samhällsansvar framträder då i de svenska rättsreglerna? Genom olika
