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2D Shear Wave Elastography, a promising screening tool for Cystic Fibrosis liver disease, shows a correlation between vitamin D and liver stiffness

Background: Liver disease in Cystic Fibrosis (CFLD) is an early complication of CF. Evidence of CFLD is often subclinical and screening is recommended. Screening includes a biochemical work-up and an ultrasound investigation. Non-invasive methods measuring liver stiffness such as shear wave elastography could be beneficial. This study describes the use of 2D Shear Wave Elastography (2D SWE) in scr

The Child's Best Interests during Hospitalisation - What does it imply?

IntroductionThe child’s best interest has moral foundations in medicine and has existed for decades in the field of paediatrics. Indeed, there are recommendations for the child’s best interests to be a primary consideration in all matters that concern the child. However, there is uncertainty in the literature over how the child’s best interests may be safeguarded within healthcare. AimThe aim of t

Non-Standard Employment and Unemployment during the COVID-19 Crisis : Economic and Health Findings from a Six-Country Survey Study

The COVID-19 crisis is a global event that has created and amplified social inequalities, including an already existing and steadily increasing problem of employment and income insecurity and erosion of workplace rights, affecting workers globally. The aim of this exploratory study was to review employment-related determinants of health and health protection during the pandemic, or more specifical

Embassy of Sharing – testbed for emerging sustainability solutions and novel business models

Sharing is considered as one of the key elements in circular economy, as well as away to deliver social impact. According to the New Bauhaus initiative by the EuropeanCommission, new neighbourhoods should be environmentally sustainable, provide anaesthetic experience, and deliver social inclusion. This study explores the emergence of sharing business models in the real estate industry. The aim is

Four walls and beyond - hybrid spaces delivering content and community

Refuse and reduce are amongst the most influential actions within Circular Economy and refer to the act of using less, reducing consumption. Within the spatial context, sharing is one way of reducing the need for physical space. Recently, other ways have emerged, such as, virtual or hybrid solutions enabling users to be part of a community and access content which would otherwise be delivered with

Does a gluten-free diet lead to better glycemic control in children with type 1 diabetes? Results from a feasibility study and recommendations for future trials

Background: Increasing evidence suggests a link between type 1 diabetes (T1D) and intake of gluten, but no controlled trials have examined whether a gluten-free diet (GFD) has positive effects on glycemic control in children with T1D. Methods: We conducted a non-randomized feasibility study. Twenty-three children with newly diagnosed T1D were included and either followed a GFD (n = 14) or a normal

Emotion and motivation in younger learners’ second foreign language acquisition

Reports and studies repeatedly indicate that foreign languages other than English are facing major challenges in European educational systems (European Commission, 2012). While young learners’ motivation to learn a second foreign language (SFL) is often reported to be low (Tholin & Lindqvist, 2009), studies have only recently started to take emotional factors into account in order to better un

Sustainability with a Cost Perspective – Driving the Industry to Embrace Sustainable Thinking

Previous research has shown that sustainable improvements need incentives to carry them through. An assumption is that it may be easier to incorporatesustainable thinking in an organization if the organization understandswhich actions it is that are having a positive effect on sustainability andon tangible costs. This paper aims to highlight the synergy effects thatoccur in the intersection betwee

An Exploratory Study of Itolizumab on the Preservation of Beta Cell Function in Adults with Recent-Onset Type 1 Diabetes

We conducted a phase I-IIa, randomized, monocentric, double-blind, placebo-controlled clinical trial to evaluate the safety and impact of the combination treatment of Itolizumab and insulin on preserving beta cell function in adults with recent-onset type 1 diabetes. Twelve patients were randomly assigned to three treatment groups, each receiving a different Itolizumab dose (0.4/0.8/1.6 mg/kg body

Changes in Vitamin D Status in Overweight Middle-Aged Adults with or without Impaired Glucose Metabolism in Two Consecutive Nordic Summers

Background. Sun exposure is the main driver of vitamin D synthesis. High latitude, obesity, and type 2 diabetes mellitus (T2DM) are all risk factors for vitamin D deficiency. However, the seasonal variation in vitamin D concentrations (25[OH]D) in such populations before and after sun exposure during the summer is unknown. Therefore, we investigated 25[OH]D status before and after two consecutive

Assessing person-centred care: An item response theory approach

Given recent advances in psychometric assessment, there is a need for assessment studies using modern test theory in the field of person-centred care, mainly due to the dominant use of analytical strategies based on classical test theory. The main objective of the present study was thus to examine whether selected items from commonly used instruments of person-centred care were able to differentia

Microbial functional genes influenced by short-term experimental drought across European agricultural fields

Agricultural intensification and extreme weather events can represent considerable stress to soil microorganisms and their functions by influencing the key players behind the degradation of soil organic matter. A better understanding of the diversity and abundance of microbial functional genes that predict the functional potential of soils, can link the microbial communities to their key ecosystem

Approaches to strengthen the Social Cohesion between Displaced and Host Communities.

A cohesive society is not only characterised by the availability of basic services and facilities, but also promotes economic equality and inclusion, democracy, and social solidarity. Forced displacement due to disasters and conflict constantly disrupt the path to a sustainable and cohesive society. Displaced communities often struggle with a lack of access to livelihood and a lack of financial in

Randomized controlled trial of nasogastric tube use after esophagectomy : study protocol for the kinetic trial

Esophagectomy is a complex and complication laden procedure. Despite centralization, variations in perioparative strategies reflect a paucity of evidence regarding optimal routines. The use of nasogastric (NG) tubes post esophagectomy is typically associated with significant discomfort for the patients. We hypothesize that immediate postoperative removal of the NG tube is non-inferior to current r

Emotive action and reaction in social science/citizenship education

Emotions are prominent in the construction of notions of citizenship. A good liberal-democratic citizen, for instance, cares about others, copes with differences and trusts the political system (Zembylas 2013). Increasing political polarization challenges teachers to prepare youth as citizens who can navigate ideological and affective boundaries (Keegan, 2021). More specifically, emotions play an

Polymorphisms in Intron 1 of HLA-DRA Differentially Associate with Type 1 Diabetes and Celiac Disease and Implicate Involvement of Complement System Genes C4A and C4B

Polymorphisms in genes in the human leukocyte antigen (HLA) class II region comprise the most important inherited risk factors for many autoimmune diseases including type 1 diabetes (T1D) and celiac disease (CD): both diseases are positively associated with the HLA- DR3 haplotype (DRB1*03:01-DQA1*05:01-DQB1*02:01). Studies of two different populations have recently documented that T1D susceptibili