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Brief Admission Skåne (BAS), an intervention for indivi- duals with symptoms of borderline personality disorder, recurrent self-harm, at high risk for suicide. : Brief admission Skåne: Evaluation of fidelity to the method and individual-therapist experiences

Objectives: To measure treatment fidelity and to evaluate patient and clinician experiences with Brief Admission Skåne (BAS) over the pilot phase and first five months of the intervention phase of a randomized controlled trial (RCT) testing BAS. The purpose of the RCT is to determine whether BAS can reduce the frequency of acute psychiatric admissions for individuals with borderline personality di

A kaleidoscope of interactions. : Researching and presenting processes of opera improvisation.

The artistic doctoral project Singing in action – processes of vocal improvisation is an investigation of vocal improvised performance from my point of view as a classically trained singer and vocal improviser. It focuses on an artistic tradition which has its roots in medieval Provence and Italy (Wilén, 2013a) and which is an expanding classical vocal genre of today: opera and art song improvisat

General purpose technology diffusion and labour market dynamics : A spatio-temporal perspective

This dissertation aims at advancing the knowledge about the role of the labour market in the process of the technology-induced economic transformation, taking into account the variety of factors involved at micro-, meso-, and macro-levels of the economy and at different geographical scales. Empirically, the dissertation investigates the co-evolutionary dynamics of industrial restructuring and work

Population genetic structure, differentiation, and diversity in Tetrix subulata pygmy grasshoppers : roles of population size and immigration

Genetic diversity within and among populations and species is influenced by complex demographic and evolutionary processes. Despite extensive research, there is no consensus regarding how landscape structure, spatial distribution, gene flow, and population dynamics impact genetic composition of natural populations. Here, we used amplified fragment length polymorphisms (AFLPs) to investigate effect

The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma

Purpose — We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background — Based on incidence rates from the literature, 8,150 (7,000–9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway,

Type 1 diabetes mellitus

Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease characterized by insulin deficiency due to pancreatic β-cell loss and leads to hyperglycaemia. Although the age of symptomatic onset is usually during childhood or adolescence, symptoms can sometimes develop much later. Although the aetiology of T1DM is not completely understood, the pathogenesis of the diseas

Stroke doctors : Who are we? A World Stroke Organization survey

Background Specialist training provides skilled workforce for service delivery. Stroke medicine has evolved rapidly in the past years. No prior information exists on background or training of stroke doctors globally. Aims To describe the specialties that represent stroke doctors, their training requirements, and the scientific organizations ensuring continuous medical education. Methods The World

Anticipating morphological and syntactic structures : investigating the pre-activation negativity

It is known that listeners can predict upcoming words based on constraining contexts (e.g. DeLong et al., 2005). In a recent study, we proposed a left frontal brain potential, the pre-activation negativity, PrAN (Söderström et al., 2016), thought to reflect pre-activation of expected word continuations. Time-locked to word-initial fragments, PrAN’s amplitude was found to increase in a 136-280 ms t

An 'alpha-beta' of pancreatic islet microribonucleotides

MicroRNAs (miRNAs) are cellular, short, non-coding ribonucleotides acting as endogenous posttranscriptional repressors following incorporation in the RNA-induced silencing complex. Despite being chemically and mechanistically very similar, miRNAs exert a multitude of different cellular effects by acting on mRNA species, whose gene-products partake in a wide array of processes.Here, the aim was to

Searching for delegated knowledge in elementary schools

Introduction. In contemporary society increased access to and dependence on digital technology has produced richer possibilities for outsourcing memory to external systems, an issue that becomes especially tangible in educational settings. The aim of this paper is to make visible how the changing relations between searching for and memorizing information is formed in the context of elementary scho

Temporal trend of autonomic nerve function and HSP27, MIF and PAI-1 in type 1 diabetes

Aim: Diabetes mellitus type 1 (T1D) has numerous complications including autonomic neuropathy, i.e. dysfunction of the autonomous nervous system. This study focuses on Heat Shock Protein 27 (HSP27), Macrophage Migration Inhibitory Factor (MIF), Plasminogen Activator Inhibitor-1 (PAI-1) and HbA1c and their possible roles in effects of diabetes on the autonomic nervous system.Methods: Patients with Aim Diabetes mellitus type 1 (T1D) has numerous complications including autonomic neuropathy, i.e. dysfunction of the autonomous nervous system. This study focuses on Heat Shock Protein 27 (HSP27), Macrophage Migration Inhibitory Factor (MIF), Plasminogen Activator Inhibitor-1 (PAI-1) and HbA1c and their possible roles in effects of diabetes on the autonomic nervous system. Methods Patients with T

Disease dynamics and bird migration-linking mallards Anas platyrhynchos and subtype diversity of the influenza a virus in time and space

The mallard Anas platyrhynchos is a reservoir species for influenza A virus in the northern hemisphere, with particularly high prevalence rates prior to as well as during its prolonged autumn migration. It has been proposed that the virus is brought from the breeding grounds and transmitted to conspecifics during subsequent staging during migration, and so a better understanding of the natal origi

Rosiglitazone drives cavin-2/SDPR expression in adipocytes in a CEBPα-dependent manner

Caveolae are abundant adipocyte surface domains involved in insulin signaling, membrane trafficking and lipid homeostasis. Transcriptional control mechanisms for caveolins and cavins, the building blocks of caveolae, are thus arguably important for adipocyte biology and studies in this area may give insight into insulin resistance and diabetes. Here we addressed the hypothesis that one of the less

High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families

BACKGROUND: : Inherited mutations in the CDKN2A tumor suppressor gene, which encodes the p16(INK4a) protein, and in the cyclin-dependent kinase 4 (CDK4) gene confer susceptibility to cutaneous malignant melanoma. We analyzed families with two or more cases of melanoma for germline mutations in CDKN2A and CDK4 to elucidate the contribution of these gene defects to familial malignant melanoma and to

Fire Behaviour of Less-Combustible Dielectric Liquids in a Nuclear Facility

Transformers, modulators and other high voltage electrical equipment are traditionally filled with mineral oil, which serves as a coolant and dielectric insulator. A rising trend is observed globally towards the adoption of less-combustible, bio-degradable transformer liquids at ever increasing voltages and power ratings. This paper presents a study of the fire behavior of five different dielectri