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OBJECTIVES: Esophageal cancer is a highly fatal malignant neoplasm, with 2 etiologically different histological types. A large prospective study is expected to elucidate the specific risk of the 90% subtype of esophageal cancer, esophageal squamous cell carcinoma (ESCC), with metformin therapy. This study aims to determine the association between metformin use and incident ESCC risk.METHODS: This

Age is a critical determinant of arterial disease, including aneurysm formation. Here, to understand the impact of aging on the arterial transcriptome, we leveraged RNA-sequencing data to define transcripts that change with advancing age in human arteries. Among the most repressed transcripts in agedindividuals were those that are relevant for actomyosin structure and organization, including both Age is a critical determinant of arterial disease, including aneurysm formation. Here, to understand the impact of aging on the arterial transcriptome, we leveraged RNA-sequencing data to define transcripts that change with advancing age in human arteries. Among the most repressed transcripts in aged individuals were those that are relevant for actomyosin structure and organization, including both

INTRODUCTION: The aim of this study was to explore long-term behavioral consequences of early versus delayed cord clamping (CC) in school-aged children. The hypothesis was that early CC would be associated with an increased risk of symptoms associated with attention deficit hyperactivity disorder (ADHD) due to the lower iron stores following early CC compared with delayed CC.METHODS: Exploratory,

Background: The use of unique national personal identification numbers (PIN) for linkage of medical records across health facilities and population-based studies is limited in sub-Saharan Africa (SSA) countries. The disintegration of healthcare research with different participant identifiers creates methodological challenges in linking data from multiple sources to answer a diverse range of policy

The purpose of this study was to examine how young people who have chosen not to drink alcohol experience themselves and their surroundings. The aim was to find out what role temperance plays in their perceived identity. I also wanted to find out how they experienced the views of them, temperance and the temperance movement in their surroundings. Finally, I was interested in the question about alc

This essay in historical archaeology deals with cultural-historical values of buildings and in this case the old train- and ferrystation in Helsingborg. The building has from the day of its opening in 1898 been exposed to threats of demolition since its original purpose was as a temporary building with intension of being replaced within a couple of years. After having seen two World Wars, even

This is a study of the work of a Danish music teacher at a free school (grade 1 9) in Copenhagen. The teaching is based explicitly on playing in ensemble and the pupils play at a high artistic level compared to a normal school. Data collection was made during three days with the help of observation, video recording and qualitative interviews. The report contains video clips where the pupils and th

This essay seeks to explore which country´s laws should be applied when a dispute concerning damages in non-contractual obligations arises från illegal copying. In Europe today we have merely a few documented laws regarding choice of law concerning illegal copying. Thus, a proposition regarding a regulation which shall control the choice of laws applied on disputes in non-contractual obligations h

This paper addresses the problem of urban transport management in Sofia ? the capital city of Bulgaria. It highlights the tensions and contradictions in the current policy and practice and suggests that the adoption of mobility management in policy making would elevate municipal capacity to deal with complex transport-environment conflicts and set the framework for a sustainable development of the