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In mouse early pachytene spermatocytes, the X and Y chromosomes undergo rapid non-homologous (NH) synapsis and desynapsis, but the functional significance remains unknown. Here, we report that pachynema-specific knockout of Speedy A (SpdyA) from telomeres caused persistent Y-X NH synapsis, with the entire Y axis synapsed onto the X axis. This persistent Y-X NH synapsis did not interrupt meiotic se

In the 2000s, same sex partnership laws, new reproductive technologies, and legislation rendering lesbian couples and single women eligible for state-funded assisted reproduction with donated gametes in the Scandinavian nations has resulted in significant changes in family formation. Drawing on two separate qualitative studies, this paper scrutinizes Scandinavia’s alleged progressive LGBTQ politic

PURPOSE: Brief Admission by self-referral (BA) is a standardized crisis-management intervention for individuals with self-harm and risk for suicide. This study explored relatives' experiences of BA. Relatives' perspectives may contribute to an increased understanding of the effects of BA given the relatives' role as support and informal caregivers as well as being co-sufferers.METHODS: Fourteen re

The increased electrification of society and the development of smart grids are often seenas central in the transition towards a more sustainable and secure energy system and necessaryto address the challenges of increasing energy demand and limited resources. Thereare many visions and ideas on what a smart grid is or could be. While most research relatedto environmental impacts on the smart grid

Hybridization allows adaptations to be shared among lineages and may trigger the evolution of new species1,2. However, convincing examples of homoploid hybrid speciation remain rare because it is challenging to demonstrate that hybridization was crucial in generating reproductive isolation3. Here we combine population genomic analysis with quantitative trait locus mapping of species-specific trait

Postural tachycardia syndrome (POTS) is a chronic autonomic disorder characterized by excessive heart rate elevation upon standing or head-up tilt, in the absence of orthostatic hypotension. This debilitating condition affects primarily young to middle-aged individuals, particularly women, and substantially influences quality of life. The main presenting symptoms are lightheadedness, palpitations,

One of the hallmarks of type 1 but also type 2 diabetes is pancreatic islet inflammation, associated with altered pancreatic islet function and structure, if unresolved. IL-1β is a proinflammatory cytokine which detrimentally affects β-cell function. In the course of diabetes, complement components, including the central complement protein C3, are deregulated. Previously, we reported high C3 expre

This anthology explores the memory work performed by Baltic and Central and East European far-right actors in the online space. Situated at the crossroads between memory studies, far-right studies, and media studies, the volume’s seven chapters show how a wide range of far-right actors, from small movements to major parties, have exploited digital communication technologies in order to establish t

Alcohol abuse is associated with an increased risk of osteopenia and fractures. Previous histomorphometric studies on iliac crest bone have found decreased bone formation and increased bone resorption in alcohol abusers but it has not been established whether alcohol abuse has any effect on the anatomical location or the healing time of tibial shaft fractures. We studied, retrospectively, 199 adul

Lathyrus vernus (L.) Bernh. is a diploid, long-lived perennial and insect-pollinated herb with no special adaptation to long-distance dispersal. It occurs on neutral soil in deciduous forests throughout western Eurasia. Due to specific habitat preferences, L. vernus has a fragmented distribution with isolated populations. We investigated allozyme variation at eleven loci in 20 populations of L. ve

The aim of the study is to examine what kind of help the elderly get, if the elderly get the help they want, how the staff treat them and how much contact they have with others than the home-help staff. Further the study looks on how the well-being of the elderly was affected by the relationship with the home-help staff and contact with other people than the home-help staff. To conduct the study i

Abstract Author: Annika Johansson, Anette Elmbert Title: The importance of attachment and the development of emotional bonds between child and drug abusing parents Keywords: attachment bond, abusive parents, treatment and health Supervisor: Anders Lundberg Assessor: Carina Tigervall The aim of this study was to examine the attachment bond between mother and child in treatment of abuse, at the

Evidence in practice The aim of this study was to discover what professionals within alcohol- and drug abuse care think about alternative treating methods in comparison to evidence based care. Also, the aim was to discover if the professionals think differently about this matter depending of their professional role within the organization. To discover this, the study was based on four qualitative