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A head and neck cancer specific questionnaire module designed to be used in quality of life assessments before, during, and after radiotherapy and surgery, with or without combinations with chemotherapy has been developed in accordance with guidelines given by the EORTC Quality of Life Study Group. Relevant issues were generated by means of literature search, and interviews with specialists and pa

Autoimmune T cell responses directed against insulin-producing β cells are central to the pathogenesis of type 1 diabetes (T1D). Detection of such responses is therefore critical to provide novel biomarkers for T1D 'immune staging' and to understand the mechanisms underlying the disease. While different T cell assays are being developed for these purposes, it is important to optimize and standardi

The aim of this paper is to compare the socio-spatial patterns of innovation and knowledge linkages of a biopharmaceutical and an agro-food biotech cluster. Dissimilarities can be expected based on differences in terms of historical technological regimes and sectoral innovation system dynamics between the agro-food and pharmaceutical industries in general and particularly the distinctive analytica

The increase of obesity and type 2 diabetes on a global scale has increased the interest in how to counteract this epidemic. Improved lifestyle in general is a fundamental approach, but other remedies such as specific weight reduction or diabetes preventive drugs and surgery have also been tested. One problem to understand is what really happens after weight loss. Ongoing studies will try to addre

EU:s deponeringsdirektiv har medfört ökade krav på deponier. Mängden deponerat organiskt material har begränsats kraftigt och deponiernas inre skall nu vara så torrt som möjligt. Konsekvenserna av detta är ännu inte helt kända. Fläskebodeponin, den deponi som varit i drift längst av de få svenska deponier som är konstruerade enligt direktivet, har här fungerat som ett exempel på framtidens depo

A growing empirical literature has investigated attitudes towards discounting of health benefits with regard to social choices of life-saving and health-improving measures and individuals' time preferences for the management of their own health. In this study, the authors elicited the time preferences of vascular surgeons in the context of management of small abdominal aortic aneurysms, for which

The present study aimed at investigating the relationship between environmental and individual factors and Stress of Conscience among nursing staff in psychiatric in-patient care. A questionnaire involving six different instruments measuring Stress of Conscience, the ward atmosphere, the psychosocial work environment, Perceived Stress, Moral Sensitivity, and Mastery was answered by 93 nursing staf

OBJECTIVE: Treatment with dopamine agonists has been associated with cardiopulmonary fibrotic reactions, predominantly in patients treated for Parkinson's disease. To our knowledge, these reactions have previously not been associated with low-dose cabergoline treatment for hyperprolactinaemia. METHOD: A case of constrictive pericarditis in a patient treated with cabergoline for hyperprolactinaemia

Studies were conducted to investigate the role of macula densa (MD)-derived nitric oxide (NO) in regulation of the glomerular filtration (GFR) through the tubuloglomerular feedback (TGF) mechanism. Immunocytochemical localization of the neuronal isoform of NO synthase (NOS) in the kidney showed that this isoform was exclusively located in MD cells. Whole kidney clearance measurements of GFR and mi

For ergonomics/human factors solutions to be beneficial for society and its members it is vital to apply a systems level perspective. Students who will be the future engineers, designers, and managers of socio-technical systems need to gain an understanding of how ergonomics/human factors can be integrated in the design of workplaces, organisations, products, and services. This paper gives example