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Pancreatic β-cell mRNA modification as a marker for type 2 diabetes
Diabetes mellitus invariably involves impaired regulation of insulin secretion from pancreatic β cells, as a result of unfavourable environmental influences in combination with aberrant expression of risk genes at either the transcriptional or the translational level. A recent report in Nature Metabolism explores a novel role of mRNA methylation in β-cell function and suggests that its downregulat
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Logistics for Rapid Isolation of Viruses From Humans
Shared reading as an intervention to improve health and well-being in adults: a scoping review
Background: Shared reading (SR) is a group reading concept consisting of weekly meetings led by a trained facilitator where literary fiction and poetry is read aloud and discussed. SR requires no previous knowledge or homework and has been tried out as a health intervention to different vulnerable populations.
Politik och styrning för hållbar konsumtion. : En forskningsöversikt
The ongoing environmental crisis and the growing socio-economic disparities between different population groups are among the most significant challenges facing humanity. These problems are rooted in unsustainable consumption patterns, particularly in the more affluent societies worldwide. We, therefore, need to change existing consumption patterns, which is a considerable challenge. A sustainable
7 Life Science Companies’Engagement with their University-basedEntrepreneurship Ecosystem: A Multi-Layered Approach
Syntetisk biologi - en hållbar lösning på klimatkrisen?
The Meridian S01E04 : Synchrotron radiation at Max IV
Animal husbandry in Iron Age Scania, with a catalogue
Institutional Barriers to PPPs: - A Case Study of a Road User Charging Development Project
A novel RHCE*02 allele, containing the single-nucleotide change c.460A>G, encodes weakened expression of C and e antigens
ESS commissioning plans
Total internal reflection fluorescence microscopy to study GLUT4 trafficking
Total internal reflection fluorescence (TIRF) microscopy is a powerful method that allows examination of plasma membrane close events in real time. The last decade, the method has successfully been used to explore GLUT4 translocation in adipocytes. Here, we describe the procedure for studying GLUT4 trafficking using TIRF microscopy in isolated primary adipocytes.
Urban planning and town foundations
Employment Protection Reform, Enforcement in Collective Agreements and Worker Flows
Practical management in Wolcott-Rallison syndrome with associated hypothyroidism, neutropenia, and recurrent liver failure : A case report
Wolcott-Rallison syndrome is a rare genetic syndrome of neonatal diabetes, liver failure, and growth retardation. We present a case with a EIF2AK3 p.(Arg902Ter) mutation, additionally complicated by hypothyroidism, impaired renal function, and exocrine pancreas insufficiency, focusing on clinical management. For its optimization, thorough care of multiple organ systems is needed.