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Objective: Long-term oxygen therapy (LTOT) during 15 h/day or more prolongs survival in patients with chronic obstructive pulmonary disease (COPD) and severe hypoxemia. No randomized controlled trial has evaluated the net effects (benefits or harms) from LTOT 24 h/day compared with 15 h/day or the effect in conditions other than COPD. We describe a multicenter, national, phase IV, non-superiority,
Water resources are under increasing pressure, and there are tensions between increasing demand and the natural limits to potable water supply. Authorities must find solutions that fulfil societal demands without compromising environmental integrity. As one way to counteract water deficits, desalination has evolved as an attractive solution. This technology is contested and associated with a varie
Research aimThis paper examines place brand communication in marginalised urban areascharacterised by low levels of attractiveness to residents, visitors and investment. Most previous research on marginalised places has focused on issues such as crime prevention and securitydevelopment, rather than on branding and attractiveness. The aim of this research is to explore the roleof place branding eff
Background: Ovarian cancer presents with non-specific symptoms that make early diagnosis challenging and the prognosis poor. Ovarian and endometrial cancers exhibit similar genomic mutations and biomarker profiles. Endogenous volatile organic compounds (VOCs) are products of metabolic activity. In cancer, metabolites increase due to tumour necrosis, leading to cancer-specific VOC patterns. The aim
The aim of Task 4.1 is to derive emission factors based on bottom-up land surface modelling, using two process-based dynamic global vegetation models (DGVMs), LPJ-GUESS and ORCHIDEE. In recent years, emission factors have been proposed as a useful methodology for estimating greenhouse gas emissions under different land-management strategies. Whilst emission factors are straightforward to implement
Access to outdoor leisure activities is central to supporting active and healthy ageing. To address the lack of research on services supporting continued engagement, this study examines how public, voluntary and private sectors provide outdoor recreation services for older adults. This study uses a qualitative research design to draw on interviews, a workshop, and field observations conducted in a
