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STUDY QUESTION: Has cumulative live birth rate (CLBR) improved over time and which factors are associated with such an improvement? SUMMARY ANSWER: During an 11-year period, 2007-2017, CLBR per oocyte aspiration increased significantly, from 27.0% to 36.3%, in parallel with an increase in blastocyst transfer and cryopreservation by vitrification. WHAT IS KNOWN ALREADY: While it has been shown that

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The general objective of the research underlying this dissertation was to conduct clinical and basic scientific studies to further elucidate the hemophilia and the coagulation process, with the goal of improving the care of families with these disorders. More specific aims were to evaluate epidemiological, genetic, clinical, and biochemical aspects of the development of inhibitors (antibodies) aga

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The air traffic control industry in Europe is under mounting pressure due to increasing air traffic and inefficient routines caused by a fragmented air space. In order to handle the demands the European Commission has launched a program entitled the Single European Sky initiative which seeks to promote a more efficient way of handling the air traffic over Europe. A reorganization of air traffic ma