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AbstractBackgroundThe role of nutrient intake in celiac disease pathogenesis is poorly understood.ObjectiveTo examine whether longitudinal childhood intake of selected vitamins and minerals is associated with celiac disease autoimmunity (CDA, primary outcome) and celiac disease (secondary outcome) in genetically at-risk children.MethodsA total of 6,520 HLA-conferred at-risk children in the observa
BackgroundSuicide is a leading cause of premature mortality worldwide, but the impact of system-level mental health resources remains unclear despite the central role of psychiatric inpatient care and declining bed capacity. Prior research has yielded inconsistent findings with limited control for confounding. We aimed to estimate the effect of psychiatric inpatient bed availability on suicide mor
Importance In randomized trials, early prophylactic hydrocortisone improved survival without bronchopulmonary dysplasia (BPD) with few adverse effects in extremely preterm infants. Large scale implementation data are needed to evaluate clinical effects and safety. Objective To examine the association between early prophylactic hydrocortisone and survival without BPD at 36 weeks’ postmenstrual age
Background: Despite advances in surgical technique and perioperative care, liver surgery remains associated with high morbidity, varying oncological outcomes and postoperative pain. This thesis evaluates aspects of the surgical technique and perioperative pain management, and their influence on the postoperative recovery, morbidity and overall survival.Methods: The thesis includes four studies. Pa
BACKGROUND: Drug-coated balloons (DCB) are frequently used during percutaneous coronary intervention. Despite this there are limited data from studies comparing different types of DCB, particularly for a paclitaxel-coated balloon (PCB) using urea as the excipient. This study aimed to assess the clinical efficacy of the PCB with urea compared with other frequently used DCB, attempting to emulate a
OBJECTIVES: To develop a group-based COMbined Fatigue Intervention (COMFI) that integrates a cognitive behavioural approach with physical activity to enhance self-management of fatigue and reduce fatigue severity and impact in people with inflammatory arthritis (IA).METHODS: The development was guided by the British Medical Research Council's framework for complex interventions and was based on: (
Background: Ensuring that national governance and healthcare systems include the organization and provision of palliative care in all care settings for all patients in need is a global imperative. In cancer care, early palliative care can improve quality of life for patients and families and receiving specialised palliative care increases opportunities for care and death in the preferred place, wh
Under den snabba urbaniseringen kring sekelskiftet 1900 införde de flesta större svenska städer så kallad reglementerad prostitution. Reglementeringen innebar att kvinnor som av polisen bedömdes sälja sex tvingades registrera sig som prostituerade och bland annat tvingades att bo och verka på av polisen anvisade gator. I Malmö låg dessa gator, med ett undantag, i den östra delen av den äldre bebyg
Many risks addressed in land use planning, such as flooding and accidents involving hazardous materials, have widely different characteristics which makes them difficult to compare. Yet, these risks sometimes need to be considered together in order to support decision-making. Furthermore, risks can sometimes affect each other, which differentiate the land use planning context from situations where
Objectives Dietary supplements may ameliorate SARS-CoV-2 infection, although scientific evidence to support such a role is lacking. We investigated whether users of the COVID-19 Symptom Study app who regularly took dietary supplements were less likely to test positive for SARS-CoV-2 infection. Design App-based community survey. Setting 445 850 subscribers of an app that was launched to enable self
Conventional social mobility research misses substantial inequalities of opportunity. To capture intergenerational persistence of family social status we need to move beyond parent-child associations in occupation or income. Models that incorporate surname group belonging show that families do not regress to a population mean at the speed implied by parent-child associations. Their mobility is fur
