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BACKGROUND: HLA-DR4, a common antigen of HLA-DRB1, has multiple subtypes that are strongly associated with risk of type 1 diabetes (T1D); however, some are risk neutral or resistant. The pathobiological mechanism of HLA-DR4 subtypes remains to be elucidated.METHODS: We used a population-based case-control study of T1D (962 patients and 636 controls) to decipher genetic associations of HLA-DR4 subt
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Many risks addressed in land use planning, such as flooding and accidents involving hazardous materials, have widely different characteristics which makes them difficult to compare. Yet, these risks sometimes need to be considered together in order to support decision-making. Furthermore, risks can sometimes affect each other, which differentiate the land use planning context from situations where
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Avhandlingen består av fyra artiklar som alla kretsar kring hur ett effektivt nyttjande av infrastruktur kan uppnås. Tre av artiklarna berör externaliteter i transportsektorn medan den fjärde artikeln rör bostadsmarknaden och hur en skattereform påverkade äldre småhusägares flyttbeteende. Externaliteter uppstår när de beslut som en person (eller företag) tar har effekter även för andra och detta iAll four papers in the thesis share a common theme: how to achieve an efficient use of infrastructure and the built environment. In the presence of externalities, pricing according to the (short-run) marginal cost is one answer on how this can be achieved and the first two papers estimates parts of the marginal cost of traffic. Paper I examines the effect of road and railway noise on property pric
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Classroom language ecologies are increasingly diverse as a result of mobility, migration, and information technology. In these spaces, interlocutors may draw upon shared linguistic and cultural resources but also bring in others. Prime examples are additional-language (AL) classrooms, where there is a shared target language, but where students may have different first languages from their classmat
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Rättsfallspodd från Juridiska fakulteten
