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An outpouring of scholarly editions: Media history perspectives on the editing of historical sources in Sweden, 1834–1847This article examines the scholarly editing of historical sources for publication in nineteenth-century Sweden. The analysis focuses on the approximately 500 letters exchanged between Hans Järta, the Director General of the National Archives of Sweden, and Bror Emil Hildebrand,
Different aspects of porphyrin proteins have been studied with theoretical methods. For example, we have studied: - The importance of hydrogen bonds for the discrimination between carbon monoxide and molecular oxygen by myoglobin, the oxygen carrier in muscles, modelling the active site both in vacuum and in the protein matrix - The inner-sphere reorganisation energy during electron transfer for
Ferrochelatase catalyses the synthesis of heme by inserting Fe(II) into protoporphyrin IX. The structure of ferrochelatase from yeast has been determined (2.4 Å). The structure is homodimeric with each of the monomer made up of two Rossmann type domains with an active-site cleft between them. Metal binding studies with Co(II) and Cd(II) ions reveal the metal binding residues as being the His-Glu
An increase in the plasma level of creatine kinase MB (CKMB) has long been used to indicate acute myocardial infarction (AMI). For optimal treatment an early diagnosis is important. An increase in the ratio between the two isoforms of CKMB is seen much earlier than an increase in the total level of CKMB. One possible method for separating these isoforms could be weak affinity chromatography (WAC).
From 1990 to 1998, estimations of the effective dose from external as well as internal irradiation from 137Cs and 134Cs were carried out for inhabitants in rural villages in the Bryansk region, Russia, highly contaminated due to the Chernobyl accident in 1986. The villages were situated about 180 km from the Chernobyl power plant and the deposition of 137Cs was in the range 0.9-2.7 MBq m-2. Yearly
Acute liver failure is accompanied by a high rate of bacterial septic complications. High portal level of lipopolysaccharide (LPS) can lead to a pronounced secretion by Kupffer cells of pro-inflammatory mediators which have been shown to be early and important mediators of liver injury. Pathogenesis of inflammatory bowel disease (IBD) is complex; involving environmental, genetic, microbial, and im
In this project, the potential of magnetic resonance (MR) imaging and spectroscopy in studies of microcirculation and haemodynamics was evaluated. The spatial and temporal characteristics of human pulsatile brain-tissue movements in healthy individuals, relevant for the understanding of the cerebrospinal-fluid (CSF) circulation and the pathogenesis of hydrocephalus, were thoroughly investigated. A
Calreticulin (CRT) is an endoplasmic reticulum (ER)-located protein involved in quality control of newly synthesized proteins as well as in calcium homeostasis of the cell. Most of what is known about CRT arises from studies of mammalian systems. However, using a Arabidopsis thaliana CRT gene expressed in mouse fibroblasts deficient of endogenous CRT, the wild type phenotype could be rescued with
The polyamines, putrescine, spermidine, and spermine, are essential for all forms of life. The polyamine biosynthetic pathway has been shown to be a potential target for drugs against various trypanosomal parasitic diseases. The two main enzymes in the biosynthesis of polyamines are ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (AdoMetDC). ODC catalyzes the first step of pol
Studies have found that depressive states in old age that do not fulfil the criteria for major depression are clinically important depressive states. These depressive states are common in primary care patients. Therefore, studies of late-life depression from a primary care perspective are needed. A depressive rating scale, Hopkins Symptom Checklist-25 (HSCL-25), was used in a community survey in 1
In this thesis, in situ doping during growth of III-V semiconductor nanowires, primarily for photovoltaic applications, is investigated. The nanowires were grown by metalorganic vapor phase epitaxy (MOVPE), with gold seed particles. After growth the nanowires were characterized using various techniques, including photoluminescence, transmission electron microscopy and electrical measurements of co
An essential part of the development of new radiopharmaceuticals for use in diagnostic nuclear medicine is the determination of its biokinetic properties. The uptake and turn-over of the radiopharmaceutical in the source organs is of great interest since this could determine whether the radiopharmaceutical would be suitable for clinical use or not. It is also important that the biokinetics and dos
Transient absorption laser spectroscopy and resonance Raman spectrscopy have been used to study conjugated polymers and oligomers. To extract more information the measurements have been compared to computer simulations and calculations. In order to obtain a better understanding of the role of conformational disorder in the photophysics of light-emitting, conjugated polymers the ultrafast transient
A new type of Bioelectronic Nanosensor Device with potential applications in medicine,biotechnology and environmental analysis was designed. The nanosensor is based on RISFET (Regional Ion Sensitive Field Effect Transistor) technology. The design of the nanosensor involves use of a set of nano-sized electrodes on the surface of a silicon chip, giving the chip the ability to sense extremely low con
Quantum dots (QDs) are semiconductor nanocrystals with quantum confinement. This thesis uses various time-resolved spectroscopic techniques to study ultrafast charge carrier dynamics in colloidal CdSe quantum dots that are important both from a theoretical point of view and for their relevance for solar cell applications. Using 2D electronic spectroscopy, we follow charge carrier relaxation and tr
Incorporation of the triamine, bis(2-diethylaminoethyl) amine as a side chain substituent on triphenylphosphine, (2S,4S)-4-diphenylphosphino-2-diphenylphosphino-methylpyrrolidine (PPM) or (R,R)-3,4-bis(diphenylphosphin)pyrrolidine (Pyrphos) gives the three new amphiphilic ligands N3P, N3PPM and N3-Pyrphos respectively. Because of the triamine functionality the distribution of the ligands and their
Thermoelectricity is being intensively researched as it is believed to hold great promise for applications in power generation and cooling. One way to quantify the electrical power output of a thermoelectric material is the power factor, a function of electrical conductivity and thermopower. There are relationships between these relevant material properties that make efficient thermoelectric mater
This thesis focuses on the magnetotransport properties of highly Mn-doped crystalline GaAs nanowires. The GaAs nanowires were first grown by metal-organic vapor phase epitaxy from gold seed particles, and subsequently implanted with Mn ions under varying conditions, e.g., ion fluence and acceleration voltage. The implantation process was carefully analyzed and optimized within the research project
Nanowires constitute one of the fundamental building blocks in assembled nanodevices. Due to the high surface to volume ratio, the fraction of surface atoms is not negligible for nanosized elements. Because of the reduced coordination of surface atoms, the physical properties deviate from those of the bulk, which influences the overall physical properties of nanostructures. Consequently, this prov
In this M.Sc. Thesis of a comparison for sewerage system of the three main municipalities of Turkish Republic of Northern Cyprus (T R N C) has been studied and discussed. The study covers the future population calculations for three municipalities, Nicosia, Famagusta and Kyrenia, by means of Turkish and European standards. The comparisons for sewerage system of the three municipalities are compare
