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In 2005 two research groups independently reported the isolation of a series of structurally intriguing C-19 terpenolides from the plants Thapsia transtagana and Thapsia garganica. The compounds were shown to be potent inhibitors of the sarco/endoplasmic reticulum Ca2+-ATPases. The interesting biological properties and the unique structural characteristics of the transtaganolides/basiliolides (the

Cytochromes P450 constitute a super-family of heme containing mixed function mono-oxygenases that is found in all branches of life. They introduce single oxygen atoms, mostly in the form of hydroxyl groups, into lipophilic substances and thereby render them more hydrophilic and susceptible to further reactions. Little is known about the bacterial cytochromes P450. I have in my thesis given an over

Ultrafine particles, their sources and fate in the atmosphere are currently key issues in atmospheric research owing to concern about their effects on human health and global climate. Traffic emissions are a dominating source of ultrafine particles, especially in urban areas. After release into the atmosphere, the particles are subjected to complex dilution and transformation processes that are of

This dissertation aims at showing that Chrétien de Troyes' Conte du Graal does not, as often affirmed, uphold traditional chivalrous values, but discloses a problematic ideology, mostly as a result of multiple interactions at the textual level. In order to examine ideology, Le Conte du Graal is analysed in the light of the poetics elaborated by Vincent Jouve in his Poétique des valeurs (2001). Fol

Calculations on a Homogeneous Charge Compression Ignition (HCCI) engine have been performed. Zero-dimensional models were used. The simplest model compressed the gas to auto-ignition, using temperature and pressure at a certain crank angle position obtained from engine experiments. It was found that calculations with good agreement could be accomplished, if using correct temperature, pressure and

This dissertation is about the way buildings archaeology approaches historical buildings. The aim is to show how buildings archaeology can be renewed and developed. The motivation is my belief that buildings archaeology does not fully utilize the potential of standing buildings as historical sources, which is mainly due to the traditional outlook on buildings as two-dimensional objects. When three

In this dissertation I have sought to test the possibility of recreating a detailed picture of an individual medieval person, tracing the Danish archbishop Absalon's own world of thought and action through those surviving sources that he has left behind. The sources are both written and material, and they include the cloister church in Sorø, the Havn Castle, the Medieval history Gesta Danorum, the

Knowledge on intermetallic compounds and alloys is essential for technology leaps. The latest of these, the so-called digital revolution, started the period of the information age which is characterized by fast information transfer. The constant development of faster and smaller electronic devices comes with the drawback of increased amounts of waste, meaning products that used to by high-end tech

The topic of the thesis is control of Homogeneous Charge Compression Ignition (HCCI) engine dynamics. HCCI offers a potential to combine high efficiency with very low emissions. In order to fulfill the potential benefits, closed-loop control is needed. The thesis discusses sensors, feedback signals and actuators for closed-loop control of the HCCI combustion. Closed-loop control of the HCCI combu

Enterprise Systems are one of the most important developments in corporate information systems during the last decade. These integrated information systems are characterized by a number of features which include a very broad scope and functionality, as well as being generic, master data, and business-process orientated. Together, these features make Enterprise Systems unique vis-à-vis other inform

The study analyses various aspects of international economics related to foreign direct investment, trade and specialisation. These issues are considered in view of the increased internationalisation - through trade and foreign direct investment - in recent decades. Special interest is devoted to the effects of economic integration. Chapter two examines the importance of FDI and country capabiliti

Very little is known about a considerable part of all proteins and it is time consuming and expensive to study each individual protein to determine its function, structure and cellular role. Proteins retain structural, functional and sequential characteristics from ancestral proteins and hence two proteins that share a common ancestor, i.e. are homologs, will to some extent have similar sequen

As a co-author of the Formula of Concord, Martin Chemnitz (1522-86) codified the sola scriptura principle of the Reformation, that the prophetic and apostolic Scriptures are the only rule for all Church doctrine. This principle is clearly expressed in Chemnitz' own theological treatises as well, but in his argumentation one is also confronted with an astonishing number of quotations from the Churc

In the beginning of the Common Era, a number of religious texts were written recounting heavenly journey adventures. These narratives have come to constitute a recurring theme in research regarding ancient religions. Round Trips to Heaven features several early Jewish and Christian heavenly journey texts. Most of them are included in the apocalyptic literature. During the earlier research, the he

One of the most common diseases occurring in old age groups is dementia. Caring for a relative with dementia poses many challenges for family caregivers and they bear the main responsibility for the persons with dementia living at home. The overall aim of this thesis, which consists of five community-based studies, was to explore experiences of burden and satisfaction among family caregivers (FC)

The focus of the environmental policy-making has shifted noticeably during the last decade. From having played a fairly insignificant role in the 1980s and earlier, product-related environmental problems have attracted an ever-increasing interest from policy-makers, especially in industrialised countries in North-Western Europe. Considerable attention has been devoted to the concept of extended pr

This study is devoted to the use of the Bible in the Greek systematic collection of Apophthegmata Patrum (AP). After an introductory survey of earlier research on the use of Scripture in general, and that of AP in particular, the main purpose of the investigation is formulated: to describe how the Bible text is contextualized, i.e., how the text is integrated with the teachings and ideals in the s

This thesis summarizes work in which time-resolved X-ray diffraction has been used to probe crystalline materials, thereby revealing the dynamics of phonons and phase transitions. X-ray diffraction is the standard tool in investigations of structure on the atomic scale. It has been used for a long time, and has successfully helped scientists to find the structure of a wide range of materials. The