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Nociceptive withdrawal reflexes (NWRs) were studied in adult rats in which the movement patterns produced by single muscles had been altered by neonatal tendon transfer. NWRs evoked by cutaneous noxious mechanical and thermal (CO2-laser) stimulation were recorded using electromyography in a decerebrate spinal preparation. The sensitivity distribution within the receptive fields of the NWRs of the
We present a statistical mechanics theory of rubber-like elasticity in swollen and unswollen polymer networks characterized by explicitly non-Gaussian distribution functions (Laplace's, Cauchy's, and continuous Poisson's in the exponential limit). An important outcome is the derivation of new families of statistical and mechanical laws, including a discussion of energy functions of strain invarian
Popular Abstract in Swedish Östrogen är ett av de viktigaste/ mest studerade kvinnliga könshormonerna som styr utvecklingen av våra fortplantningsorgan och deras reproduktionsförmåga. Östrogen påverkar dessutom många av kroppens andra organ, bland annat hjärnan, skelettet, och hjärt-kärlsystemet. Mängden östrogen som finns i kroppen varierar vanligtvis under menstruationscykeln och med kvinnans ålEstrogen effects are mediated either through genomic action involving the classical estrogen receptors, estrogen receptor alpha (ERα) and beta (ERß), which function as transcription factors in the nucleus, or through rapid non-genomic action via receptors associated with plasma membrane. Recently, a member of the G protein-coupled receptor family was ascribed estrogen receptor properties and propo
A cohesive interface model based on a master curve is proposed for the analysis of delamination in paperboard under various loading, unloading, and reloading conditions. The model is thermodynamically consistent and considers the effects of elasticity, plasticity, and damage. The proposed model is verified by comparing its predictions with experimental data obtained from multiple loading–unloading
Popular Abstract in Swedish Nervsignaler som förmedlar känsel från huden och kommandon till kroppsmuskulaturen passerar genom ryggmärgen eller dess motsvarighet i hjärnstammen. Kunskap om hur ryggmärgens nervkretsar är uppbyggda och hur de bearbetar nervsignaler är därför av fundamental betydelse för att kunna förstå och behandla exempelvis smärta och ryggmärgskador. I detta avhandlingsarbete studPrinciples for sensorimotor transformation and plasticity in the spinal cord and functional repair in the root-avulsed spinal cord were studied. A comparative study confirmed that the nociceptive withdrawal reflex (NWR) system is composed of reflex modules, with each performing a finely tuned transformation of skin sensory input to activity in one muscle. This suggests that modularity of the NWR s
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) in which oligodendrocytes, the CNS cells that stain most robustly for iron and myelin are the targets of injury. Metals are essential for normal CNS functioning, and metal imbalances have been linked to demyelination and neurodegeneration. Using a multidisciplinary approach involving synchro
PURPOSE: To study the feasibility of an interleaved gradient-echo, echo-planar imaging (iGE-EPI) sequence for multiplanar magnetic resonance temperature imaging (MRTI) to monitor intracerebral thermal treatment three-dimensionally using multielement ultrasound applicators.MATERIALS AND METHODS: Transmissible venereal tumor (TVT) fragments were injected into the right cerebral hemisphere of five do
A significant part of non-exhaust particle emissions in cities comes from the wear of vehicle components. Several studies on airborne particles from the wear of disc brakes and tires have been completed. However, few publications can be found in the scientific literature regarding airborne emissions from dry clutches used in road vehicles. With this in mind, this preliminary study designs a clutch
Popular Abstract in Swedish Tjocktarmcancer är en av de vanligaste cancerformerna i västvärlden. I Sverige drabbas årligen ca 5000 människor. Ungefär 10% av fallen går att härleda till ärftliga faktorer medan den övervägande delen orsakas av miljöfaktorer. Kända riskfaktorer är fysisk inaktivitet, fetma och rökning. Risken för cancer påverkas dock mest av den kost vi äter. Allmänt kan sägas att enSphingomyelin (SM) is present both in eucaryotic cells and the diet. Sphingomyelinase (SMase) hydrolyses SM and generates ceramide that has been implicated in the regulation of cell growth, differentiation and apoptosis. Previously a SMase with alkaline pH optimum was identified in the intestinal tract. The thesis studied the distribution pattern, the species difference and the clinical implicatio
Kvaliteten på kliniska bilder har stor betydelse för korrekt medicinsk diagnostik. I konventionella morfologiska MR-bilder är signalen normalt relativt hög i förhållande till bruset. Vissa nya MR-metoder för s.k. funktionsdiagnostik bygger emellertid på en avsiktlig degradering av signalen för att vissa kvantitativa parametrar skall kunna beräknas. I sådana studier kan följaktligen signal-till-bruNoise is a well-known problem in many imaging modalities. In magnitude magnetic resonance images, obtained by quadrature detection, the associated Rician distribution of noise constitutes a further complication. This type of noise is especially problematic at low signal-to-noise ratio (SNR) regions. The Rician noise distribution causes a non-zero minimum signal in the image, often referred to as t
In recent years several aids for automated interpretation of visual field data have been suggested. We believed that incorporation of thorough knowledge of normal visual field variability would allow improvements in the performance of such aids since more attention would be paid to field results in areas with low physiological variability. Two visual field models for classification of fields in gl
The advancements in biometric technology have amplified the need for more robust fingerprint synthesis techniques. In this thesis, we first explored the application of synthesizing normal fingerprint images in high fidelity using deep generative models (e.g., generative adversarial networks and diffusion models) and created synthetic fingerprints that retain the uniqueness and complexity of the or
Popular Abstract in Swedish Information om vår omvärld förmedlas med hjälp av elektriska och kemiska signaler i kroppens olika nervbanor till hjärnan där vi tolkar signalerna. Dessa s.k. sensoriska signaler förmedlar information om så skilda saker som hur maten smakar till hur varmt det är, hur ett föremål ser ut, känns osv, till smärtinformation som hjälper oss att undvika farliga situationer. I Neuropeptide expression in the nervous system is abundant and plastic, and an altered expression after injury is an example of a functional response, helping the neuron to cope with adverse changes, and involves effects on differentiation, synthesis, repair/regeneration, survival, and modulation of signal transmission. I have investigated the distribution/expression of the neuropeptides, orphanin
Popular Abstract in Swedish Det är välkänt att utflödesobstruktion kan leda till förstoring av blåsan med åtföljande minskning av kontraktionskraften, något som kan påvisas både in vivo och in vitro. I arbete I undersöktes därför om det fanns regionala skillnader i blåsmuskelfunktion hos kaniner med experimentell utflödesobstruktion. Efter 2 veckors obstruktion utfördes cystometri och därefter undThe consequences of bladder outlet obstruction (BOO) with respect to detrusor hypertrophy, structural and functional changes, and obstruction-induced detrusor overactivity were investigated in vivo and in vitro utilizing various animal models. Possible pathophysiological pathways and therapeutic approaches were tested by drug treatment and the use of knockout models. Furthermore the role of estrog
Cancer är en otrevlig sjukdom, som drabbar många människor. Man söker ständigt nya och bättre sätt att bota patienter eller åtminstone lindra sjukdomens framfart. Ett vanligt sätt att behandla cancer är med strålning. Strålningen kan bestå av sk fotoner. Fotoner är samma slags partiklar som t.ex. vanligt ljus. Skillnaden är att de fotoner som används vid strålbehandling av cancer har högre energi "Purpose: The aim of this study was to investigate whether inversely planned intensity modulated radiation therapy (IMRT), using the clinical radiotherapy equipment at hand in our department, renders any advantages regarding dose distribution over conventional radiotherapy for head and neck cancer patients in the ARTSCAN (Accelerated RadioTherapy of Squamous cell Carcinoma in the head And Nec
Aims: The Atrophodermas include a large group of disorders appearing as localized or widespread depressed skin areas and characterized by underlying dermal atrophy. The present study aims to report a peculiar form of previously unreported focal dermal atrophy. Methods: We studied over a period of 5 years a boy who manifested, since birth, multiple hypopigmented cutaneous atrophic lesions of the at
Popular Abstract in Swedish Behandling med radionuklidterapi baseras på radioaktiva läkemedel, d.v.s. läkemedel som i sig består av ett radioaktivt ämne, eller som kopplats till en radionuklid. Den strålningsenergi som avges vid de radioaktiva sönderfallen absorberas i vävnad och ger en lokalt absorberad stråldos där läkemedlet tas upp. Viktigt är härvid att upptaget är högre i patologisk vävnad äIndividual-based determinations of the absorbed dose in radionuclide therapy largely rely on absolute measurement of the activity distribution and its redistribution over time. Scintillation-camera imaging is the most commonly employed measuring technique, applied in planar or SPECT mode, sometimes in combination with structural images from CT. In this thesis, methods for processing and analysis o
This thesis is focused on electronic cigarettes and the formulations (also known as e-juices) associated with these. The reason is that there have been countless studies on the health effects and nicotine delivery of normal cigarettes, but not as much on electronic cigarettes. This work aims to provide some insights into how electronic cigarettes behaves as nicotine delivery system. The overall re
Brevmall Postadress Box 117, 221 00 Lund Besöksadress MNO-huset Sölvegatan 16 Telefon 046-222 84 31, 046-222 00 00 E-post ulrika.verngren@service.lu.se Förva l tn ingschefen Posthantering vid Lunds universitet Bakgrund Sedan 2002 har antalet brev som skickas i Sverige minskat med ca 30 procent. Denna förändring syns också inom Universitetsposten. I verksamhetsdialog med samtliga fakulteter har fra
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/posthantering-vid-lunds-universitet.pdf - 2026-10-05
