SHANK genes code for scaffold proteins located at the post-synaptic density of glutamatergic synapses. In neurons, SHANK2 and SHANK3 have a positive effect on the induction and maturation of dendritic spines, whereas SHANK1 induces the enlargement of spine heads. Mutations in SHANK genes have been associated with autism spectrum disorders (ASD), but their prevalence and clinical relevance remain t

Background: Results from several cohort and case-control studies suggest a protective association between current alcohol intake and risk of thyroid carcinoma, but the epidemiological evidence is not completely consistent and several questions remain unanswered. Methods: The association between alcohol consumption at recruitment and over the lifetime and risk of differentiated thyroid carcinoma wa

Fruit and vegetable (F&V) intake is considered as probably protective against overall cancer risk, but results in previous studies are not consistent for thyroid cancer (TC). The purpose of this study is to examine the association between the consumption of fruits, vegetables, fruit juices and differentiated thyroid cancer risk within the European Prospective Investigation into Cancer and Nutr

Purpose: Coffee and tea constituents have shown several anti-carcinogenic activities in cellular and animal studies, including against thyroid cancer (TC). However, epidemiological evidence is still limited and inconsistent. Therefore, we aimed to investigate this association in a large prospective study. Methods: The study was conducted in the EPIC (European Prospective Investigation into Cancer

To identify common alleles associated with different histotypes of epithelial ovarian cancer (EOC), we pooled data from multiple genome-wide genotyping projects totaling 25,509 EOC cases and 40,941 controls. We identified nine new susceptibility loci for different EOC histotypes: six for serous EOC histotypes (3q28, 4q32.3, 8q21.11, 10q24.33, 18q11.2 and 22q12.1), two for mucinous EOC (3q22.3 and

BackgroundPregnant women who gain excess weight are at risk of complications during pregnancy and in the long term. Interventions based on diet and physical activity minimise gestational weight gain with varied effect on clinical outcomes. The effect of interventions on varied groups of women based on body mass index, age, ethnicity, socioeconomic status, parity, and underlying medical conditions

There is a growing evidence of the protective role of the Mediterranean diet (MD) on cancer. However, no prospective study has yet investigated its influence on lymphoma. We evaluated the association between adherence to the MD and risk of lymphoma and its subtypes in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. The analysis included 476,160 participants, recruite

Introduction: Chronic inflammation plays a critical role in lymphomagenesis and several dietary factors seem to be involved its regulation. The aim of the current study was to assess the association between the inflammatory potential of the diet and the risk of lymphoma and its subtypes in the European Investigation into Cancer and Nutrition (EPIC) study. Methods: The analysis included 476,160 sub

Background: Activated phosphoinositide 3-kinase δ syndrome (APDS) 2 (p110δ-activating mutations causing senescent T cells, lymphadenopathy, and immunodeficiency [PASLI]-R1), a recently described primary immunodeficiency, results from autosomal dominant mutations in PIK3R1, the gene encoding the regulatory subunit (p85α, p55α, and p50α) of class IA phosphoinositide 3-kinases. Objectives: We sought

The advent of high-resolution magnetic resonance imaging (MRI) has enabled in vivo research in a variety of populations and diseases on the structure and function of hippocampal subfields and subdivisions of the parahippocampal gyrus. Because of the many extant and highly discrepant segmentation protocols, comparing results across studies is difficult. To overcome this barrier, the Hippocampal Sub

Bile acids (BAs) play different roles in cancer development. Some are carcinogenic and BA signaling is also involved in various metabolic, inflammatory and immune-related processes. The liver is the primary site of BA synthesis. Liver dysfunction and microbiome compositional changes, such as during hepatocellular carcinoma (HCC) development, may modulate BA metabolism increasing concentration of c

Hepatocellular carcinoma (HCC) development entails changes in liver metabolism. Current knowledge on metabolic perturbations in HCC is derived mostly from case-control designs, with sparse information from prospective cohorts. Our objective was to apply comprehensive metabolite profiling to detect metabolites whose serum concentrations are associated with HCC development, using biological samples

Open science and collaboration are necessary to facilitate the advancement of Parkinson’s disease (PD) research. Hackathons are collaborative events that bring together people with different skill sets and backgrounds to generate resources and creative solutions to problems. These events can be used as training and networking opportunities, thus we coordinated a virtual 3-day hackathon event, duri

Verksamhetsberättelse 2014 | LUNDS UNIVERSITETS BIBLIOTEK Redaktör: Lena Landgren Omslagsfoto: Fredrik Vanek Innehållsförteckning 1. Inledning.................................................................... 4 1.1 Biblioteksorganisationen ....................................... 4 Lunds universitets bibliotek................................... 4 Biblioteksstyrelsen ..............................

https://www.lub.lu.se/sites/lub.lu.se/files/vb_lub_2014.pdf - 2025-07-28

ÖVERVAKNING AV FÅGLARNAS POPULATIONSUTVECKLING Årsrapport för 2024 ÖVERVAKNING AV FÅGLARNAS POPULATIONSUTVECKLING Årsrapport för 2024 MARTIN GREEN, FREDRIK HAAS & ÅKE LINDSTRÖM | LUNDS UNIVERSITET Övervakning av fåglarnas populationsutveckling Årsrapport för 2024 Martin Green, Fredrik Haas & Åke Lindström Innehållsförteckning .......................................... .............................

https://www.fageltaxering.lu.se/sites/fageltaxering.lu.se/files/2025-04/arsrapport2024_del1.pdf - 2025-07-28

Professor Kontaktinformation E-post: ulf [dot] gerdtham [at] med [dot] lu [dot] se Telefon: +46 46 222 48 10 Mobil: +46 76 887 12 04Organisation Hälsoekonomi Rumsnummer: alfa 4005, BMC E15 Hämtställe: 90 WebbplatsUlf Gerdthams profil i Lunds universitets forskningsportalPersonlig webbplats:https://sites.google.com/site/ulfgerdtam/Andra roller Forskargruppschef Hälsoekonomi Professor Nationalekonom

https://www.ehl.lu.se/ulf-gerdtham - 2025-07-27

lum_2006_08 LUM Lunds universitets magasin | Nr 8 | 2006 sLäkten är bäst! Inredningspengar tog slut på SOL Politikerfritt i styrelsen? LUM nr 8 | 2006 MersMak LUM nr 8 | 2006 Det gick åt cirka 0 kilo choklad för att hålla igång den mörkt drop- pande chokladfontänen som blev många barns höjdpunkt under Ve- tenskapskarnevalen. Kakao var te- mat i den deckargåta som främst mellanstadiebarn från hel

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-8-2006.pdf - 2025-07-28

Professor Kontaktinformation E-post: tommy [dot] bengtsson [at] ekh [dot] lu [dot] se Telefon: +46 46 222 73 80Organisation Ekonomisk-historiska institutionen Besöksadress: Scheelevägen 15 B, Lund Rumsnummer: Alfa 1:2021 Hämtställe: 10 WebbplatsTommy Bengtssons profil i Lunds universitets forskningsportalAndra roller Professor Centrum för ekonomisk demografi Professor EpiHealth: Epidemiology for H

https://www.ehl.lu.se/tommy-bengtsson - 2025-07-27

Professor emeritus Kontaktinformation E-post: per [dot] wickenberg [at] soclaw [dot] lu [dot] se Telefon: +46 46 222 88 15 Mobil: +46 72 741 82 72Organisation Rättssociologiska institutionen Hämtställe: 31 WebbplatsPer Wickenbergs profil i Lunds universitets forskningsportalAndra roller Profilområdesmedlem LU profilområde: Mänskliga rättigheterForskningsområdenNormer och normbildning inom utbildni

https://www.soclaw.lu.se/wickenberg - 2025-07-27