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07-Farligt-avfall-Smittforande-biologiskt-lakemedelsavfall-250110

Avfallshandbok: Del 7. Farligt avfall – smittförande, biologiskt och läkemedelsavfall Sida 1 av 14 Diarienummer: V 2024/2581 Handlingstyp: 2.3.2 Rutin Ämnesområde: Miljöledning Gäller för: Lunds universitet Datum: 2025-01-01 Version: 1.0 Framtaget av: Miljöfunktionen, LU Byggnad Godkänd av: Miljöchef Avfallshandbok: Del 7. Farligt avfall – smittförande, biologiskt och läkemedelsavfall Denna rutin

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2025-01/07-Farligt-avfall-Smittforande-biologiskt-lakemedelsavfall-250110.pdf - 2025-12-16

Den utvidgade straffskalan för mord - En studie av straffmätningen i tingsrätt och hovrätt

Murder is the most serious crime of violence according to Swedish law. The punishment for a person who commits a murder has been either 10 years or a lifetime in imprisonment since the year of 1965. In order to create a more nuanced sentencing for murder and increased punishments for murders that do not give rise to life imprisonment imposed on 1 July 2009 an expanded scale of punishment for murde

Thyroid-Stimulating Hormone, Thyroglobulin, and Thyroid Hormones and Risk of Differentiated Thyroid Carcinoma: The EPIC Study

Background Increased levels of thyroglobulin (Tg) and thyroid-stimulating hormone (TSH) are associated with differentiated thyroid carcinoma (TC) risk, but strong epidemiological evidence is lacking. Methods Three hundred fifty-seven incident TC case patients (n = 300 women and 57 men; mean age at blood collection = 51.5 years) were identified in the EPIC cohort study and matched with 2 (women) or

Polyphenol intake and differentiated thyroid cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Polyphenols are bioactive compounds with several anticarcinogenic activities; however, human data regarding associations with thyroid cancer (TC) is still negligible. Our aim was to evaluate the association between intakes of total, classes and subclasses of polyphenols and risk of differentiated TC and its main subtypes, papillary and follicular, in a European population. The European Prospective

Energy and macronutrient intake and risk of differentiated thyroid carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.

Incidence rates of differentiated thyroid carcinoma (TC) have increased in many countries. Adiposity and dietary risk factors may play a role, but little is known on the influence of energy intake and macronutrient composition. The aim of this study is to investigate associations between TC and the intake of energy, macronutrients, glycemic index (GI) and glycemic load in the European Prospective

Insulin-like Growth Factor-I and Risk of Differentiated Thyroid Carcinoma in the European Prospective Investigation into Cancer and Nutrition

Background: Little is known about the causes of thyroid cancer, but insulin-like growth factor-I (IGF-I) might play an important role in its development due to its mitogenic and antiapoptotic properties. Methods: This study prospectively investigated the association between serum IGF-I concentrations and risk of differentiated thyroid carcinoma in a case-control study nested within the European Pr

Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort.

Hepatocellular carcinoma (HCC), the most prevalent form of liver cancer, is difficult to diagnose and has limited treatment options with a low survival rate. Aside from a few key risk factors, such as hepatitis, high alcohol consumption, smoking, obesity, and diabetes, there is incomplete etiologic understanding of the disease and little progress in identification of early risk biomarkers.

Fruit and vegetable intake and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Several dietary factors have been studied in relation to prostate cancer; however, most studies have not reported on subtypes of fruit and vegetables or tumor characteristics, and results obtained so far are inconclusive. This study aimed to examine the prospective association of total and subtypes of fruit and vegetable intake with the incidence of prostate cancer overall, by grade and stage of d

Blood Metabolic Signatures of Body Mass Index : A Targeted Metabolomics Study in the EPIC Cohort

Metabolomics is now widely used to characterize metabolic phenotypes associated with lifestyle risk factors such as obesity. The objective of the present study was to explore the associations of body mass index (BMI) with 145 metabolites measured in blood samples in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Metabolites were measured in blood from 392 men from t

Characteristics of children and young adults with Marfan syndrome and aortic root dilation in a randomized trial comparing atenolol and losartan therapy

BACKGROUND: The Pediatric Heart Network designed a clinical trial to compare aortic root growth and other short-term cardiovascular outcomes in children and young adults with Marfan syndrome randomized to receive atenolol or losartan. We report here the characteristics of the screened population and enrolled subjects.METHODS AND RESULTS: Between 2007 and 2011, 21 clinical sites randomized 608 subj

Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition

Background: The mechanisms underlying the obesity-cancer relationship are incompletely understood. This study aimed to characterise metabolic signatures of greater body size and to investigate their association with two obesity-related malignancies, endometrial and colorectal cancers, and with weight loss within the context of an intervention study. Methods: Targeted mass spectrometry metabolomics

Novel Biomarkers of Habitual Alcohol Intake and Associations with Risk of Pancreatic and Liver Cancers and Liver Disease Mortality

BACKGROUND: Alcohol is an established risk factor for several cancers, but modest alcohol-cancer associations may be missed due to measurement error in self-reported assessments. Biomarkers of habitual alcohol intake may provide novel insight into the relationship between alcohol and cancer risk.METHODS: Untargeted metabolomics was used to identify metabolites correlated with self-reported habitua

Impacts of climate change on surface hydrology in the source region of the Yellow River

Popular Abstract in Swedish Nästan 35% av den totala avrinningen i Gula floden härstammar från dess källområde och vattenförsörjningen nedströms är därför beroende av de rådande förhållandena i detta område. Minskad vattenföring i floden på grund av klimatförändringar förväntas leda till negativa konsekvenser för de 110 miljoner invånarna i avrinningsområdet och problem uppstår för såväl jordbrukeThe source region of the Yellow River contributes about 35% of the total water yield in the Yellow River basin playing an important role for meeting the downstream water resources requirements. The declining water availability caused by climate change in the source region of the Yellow River is expected to have severe repercussions for the 110 million basin inhabitants in terms of water resources

Dietary methyl-group donor intake and breast cancer risk in the european prospective investigation into cancer and nutrition (EPIC)

(1) Background: Methyl-group donors (MGDs), including folate, choline, betaine, and methionine, may influence breast cancer (BC) risk through their role in one-carbon metabolism; (2) Methods: We studied the relationship between dietary intakes of MGDs and BC risk, adopting data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort; (3) Results: 318,686 pre-and postmen

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

Genetic studies promise to provide insight into the molecular mechanisms underlying type 2 diabetes (T2D). Variants associated with T2D are often located in tissue-specific enhancer clusters or super-enhancers. So far, such domains have been defined through clustering of enhancers in linear genome maps rather than in three-dimensional (3D) space. Furthermore, their target genes are often unknown.

Haplotypes of the estrogen receptor beta gene and breast cancer risk

Exposure to exogenous (oral contraceptives, postmenopausal hormone therapy) and endogenous (number of ovulatory cycles, adiposity) steroid hormones is associated with breast cancer risk. Breast cancer risk associated with these exposures could hypothetically be modified by genes in the steroid hormone synthesis, metabolism and signaling pathways. Estrogen receptors are the first step along the pat

Selection criteria for genetic assessment of patients with familial melanoma

Approximately 5% to 10% of melanoma may be hereditary in nature, and about 2% of melanoma can be specifically attributed to pathogenic germline mutations in cyclin-dependent kinase inhibitor 2A (CDKN2A). To appropriately identify the small proportion of patients Who benefit most from referral to a genetics specialist for consideration of genetic testing for CDKN2A, We have reviewed available publi

Hand injuries - epidemiology, costs and outcome

Popular Abstract in Swedish Händerna utsätts dagligen för olika typer av faror. Handskador av varierande omfattning är därför inte ovanliga. Dessa kan drabba både barn och vuxna, såväl under fritiden som i arbetslivet. Panoramat av handskador har förändrats. För omkring 40 år sedan var handskador vanligt förekommande på arbetsplatsen, men har sedan dess minskat så att de för 20 år sedan utgjorde uHand injuries have a profound impact not only on the patient’s activity of daily living and during leisure time but also on working capability. Such injuries may therefore also generate substantial costs for society in terms of sick-leave and treatment. In the present thesis, the panorama, costs (within the health-care system, due to lost production and total costs), outcome and health status of p

Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition

Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estim

Lymphatic Disorder Management in Pediatric Patients With Congenital Heart Disease in European Pediatric Cardiology Centers : Current Status, Disparities, and Future Considerations

BACKGROUND: Lymphatic disorders such as protein-losing enteropathy, plastic bronchitis, and chylothorax are important complications of the Fontan circulation and ultimately result in an increased risk of early death. Several European centers are now performing lymphatic procedures. The aim of this study is to map the extent of these lymphatic disorders and treatments provided across European pedia