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Indistinguishable genomic profiles and shared prognostic markers in undifferentiated pleomorphic sarcoma and leiomyosarcoma: different sides of a single coin?
Soft tissue sarcoma (STS) diagnostics and prognostics are challenging, particularly in highly malignant and pleomorphic subtypes such as undifferentiated pleomorphic sarcoma (UPS) and leiomyosarcoma (LMS). We applied 32K BAC arrays and gene expression profiling to 18 extremity soft tissue LMS and 31 extremity soft tissue UPS with the aim of identifying molecular subtype signatures and genomic prog
Are aggressive pituitary tumors and carcinomas two sides of the same coin? Pathologists reply to clinician’s questions
Pituitary adenohypophyseal tumors are considered as benign and termed “adenomas”. However, many tumors are invasive and a proportion of these exhibit an “aggressive behavior” with premature death due to progressive growth. Only very rare (0.2%) tumors with metastases are considered malignant and termed “carcinomas”. Taking into account this variability in behavior and the oncological definition, p
Public diplomacy and development communication : Two sides of the same coin?
This chapter seeks to develop a theoretical basis for better understanding the intersections between public diplomacy (PD) and development communication (Devcom). It will be argued that both fields involve (1) theories of influence over social change in foreign countries; (2) a voluntary transfer of resources from an actor promoting a specific cause or agenda to a group or organization in a foreig
Coagulation Systems of Invertebrates and Vertebrates and Their Roles in Innate Immunity: The Same Side of Two Coins?
Bacterial infections represent a serious health care problem, and all multicellular organisms have developed defense mechanisms to eliminate pathogens that enter the host via different paths including wounds. Many invertebrates have an open circulatory system, and effective coagulation systems are in place to ensure fast and efficient closure of wounds. It was proposed early on that coagulation sy
Aggressive pituitary tumours and carcinomas : two sides of the same coin?
The European Society of Endocrinology (ESE) survey reported on the largest cohort of 125 aggressive pituitary tumours (APT) and 40 pituitary carcinomas (PC). Whilst the survey focused on treatment effectiveness, all pathological data were not explored in detail. Here, we comment on some interesting pathological findings, notably the difference between APT and PC.
The Other Side of the Coins : The Environmental Impact of Greenfield FDI in Sub-Saharan Africa´s Pollution-Intensive Industries and the Role of Governance
While foreign direct investments (FDI) are promoted as a vehicle for economic development their environmental consequences are less estab-lished. This study tests the hypotheses that 1) FDI led to environmental deg-radation in form of increased greenhouse gas emissions during Sub-Saharan Africa´s recent growth spurt but that 2) this impact was felt to a lesser extent in countries with a higher qua
Two sides of the same coin : The experiences of high-achieving women in the Swedish workplace
Adopting a qualitative approach to the investigation of high achievement, the authors analyzed how high-achieving women in the Swedish workplace made meaning of positive and negative experiences in their work. The data consisted of interviews with 15 women identified as being high achieving in their respective field, and it was analyzed using grounded theory methodology. The women described five d
Reconstructing Stobaeus's lost collection of coins and medals
Among farmers and city people : coin use in early medieval Denmark c. 1000-1250
The other side of the coin: the e-government implementation in an Italian municipality
This paper ad to the body of knowledge on the implementation ofthe e-Government and aims to describe how this process was carried out inthe Delta municipality in Northern Italy. This organization is a public organization in an economically important Region and provides services to entrepreneurs such as validation for opening a new business. An interpretativeapproach used with several interviewees
Bet on both sides of the coin to improve the organizational climate: The impact of congruent task and role clarity between leaders and staff
Four organizations at Stockholm-Arlanda airport are going through various organizational changes. They are preparing for present and future demands through structural changes, implementation of new technology, training, and other efficiency and capacity improving measures. The change processes will be followed during two years of which this paper presents the baseline measurement. The key factors
Anandamide - The other side of the coin
Coins and People in Central Blekinge
Reply to 'Blood pressure during moderate or maximal exercise : hardly two sides of the same coin'
Coins have both sides : Revealing the structure and pattern of global interdependence network for five critical metals
Evaluating the trade interdependence among countries is the key to understanding critical metal minerals security. By constructing a novel interdependence network, this paper reveals a more comprehensive world hierarchy and risk system of critical metals, and focuses on the interdependencies between China and the US-led MSP countries before and after the Sino-US trade disputes. The results indicat
The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A
Demonstration of the non-identity between the Fc receptor for human IgG from group A streptococci type 15 and M protein, peptidoglycan and the group specific carbohydrate
Fc epsilon RI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis
The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. However, their respective roles in allergic diseases, such as rhinitis, are unclear.
