Filetype
The uptake and killing of bacteria by human neutrophils are dependent on the fusion of secretory granules with forming phagosomes. The earliest component of exocytosis was found to precede phagosome closure, so that granular membrane constituents were detectable on the plasmalemma. We show that during phagocytosis of IgG-opsonized particles, this early secretory response is highly polarized in the
Background: p21-activated kinase 1 (Pak1) phosphorylates many proteins in both normal and transformed cells. Its ability to phosphorylate and thereby activate the estrogen receptor alpha (ER alpha) potentially limits the effectiveness of antiestrogen treatment in breast cancer. Here we studied associations between Pak1 expression and subcellular localization in tumor cells and tamoxifen resistance
C2MDS#090606 1..6 Brief Report Characterization of Lewy Body Pathology in 12- and 16-Year-Old Intrastriatal Mesencephalic Grafts Surviving in a Patient With Parkinson’s disease Jia-Yi Li, MD, PhD,1* Elisabet Englund, MD,2 Håkan Widner, MD, PhD,3 Stig Rehncrona, MD,4 Anders Björklund, MD,5 Olle Lindvall, MD, PhD,3,6 and Patrik Brundin, MD, PhD1 1Neuronal Survival Unit, Wallenberg Neuroscience Cen
https://www.wnc.lu.se/sites/wnc.lu.se/files/li_et_al_mvdis_2010.pdf - 2026-10-02
OP-BRAI160351 1..15 Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli Daniel Tornero,1 Oleg Tsupykov,2 Marcus Granmo,3 Cristina Rodriguez,1 Marita Grønning- Hansen,1 Jonas Thelin,3 Ekaterina Smozhanik,2 Cecilia Laterza,1 Somsak Wattananit,1 Ruimin Ge,1 Jemal Tatarishvili,1 Shane Grealish,4 Oliver Brüstle,5 Galina Skibo,2 Malin Parmar
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_brain.pdf - 2026-10-02
Activity in grafted human iPS cell–derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior Activity in grafted human iPS cell–derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior Sara Palma-Tortosaa,1, Daniel Torneroa,b,1 , Marita Grønning Hansena, Emanuela Monnia, Mazin Hajya, Sopiko Kartsivadzea,c, Sibel Aktaya, Oleg Tsupykov
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_pnas_6.pdf - 2026-10-02
Embedded 3D Printing in Self‐Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs RESEARCH ARTICLE www.advancedscience.com Embedded 3D Printing in Self-Healing Annealable Composites for Precise Patterning of Functionally Mature Human Neural Constructs Janko Kajtez,* Milan Finn Wesseler, Marcella Birtele, Farinaz Riyahi Khorasgani, Daniella Rylander Ot
Identification and validation of novel engineered AAV capsid variants targeting human glia Frontiers in Neuroscience 01 frontiersin.org Identification and validation of novel engineered AAV capsid variants targeting human glia Jessica Giacomoni 1, Malin Åkerblom 2, Mette Habekost 1, Alessandro Fiorenzano 1, Janko Kajtez 1, Marcus Davidsson 2, Malin Parmar 1 and Tomas Björklund 2* 1 Developmental a
let‐7 regulates radial migration of new‐born neurons through positive regulation of autophagy Article let-7 regulates radial migration of new-born neurons through positive regulation of autophagy Rebecca Petri, Karolina Pircs, Marie E Jönsson, Malin Åkerblom, Per Ludvik Brattås, Thies Klussendorf & Johan Jakobsson* Abstract During adult neurogenesis, newly formed olfactory bulb (OB)
https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/embj.201695235.full_.pdf - 2026-10-02
ANNUAL REPORT FOR 2017 HISTORY 1988 The Nanometer Structure Consortium (nmC) is initiated 1995 SSF funds nmC with several major grants until 2012 2000 Major nanowire research programme initiated 2003 Undergraduate education programme in Engineering Nanoscience starts 2007 Inauguration of Lund Nano Lab 2010 Strategic Research Area funded by the Swedish Government 2015 nmC becomes NanoLund, the Cent
https://www.nano.lu.se/sites/nano.lu.se/files/arsrapport_nanolund_2017_ed2_web.pdf - 2026-10-02
Research Article Directly Converted Human Fibroblasts Mature to Neurons and Show Long-Term Survival in Adult Rodent Hippocampus Natalia Avaliani,1 Ulrich Pfisterer,2 Andreas Heuer,2,3 Malin Parmar,2 Merab Kokaia,1 and My Andersson1 1Epilepsy Centre, Lund University Hospital, Lund, Sweden 2Developmental Neurobiology, Lund University, Lund, Sweden 3Molecular Neuromodulation, Lund University, Lund, S
Journal of Visualized Experiments www.jove.com Copyright © 2019 Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License June 2019 | 148 | e59465 | Page 1 of 9 Video Article In Vivo Direct Reprogramming of Resident Glial Cells into Interneurons by Intracerebral Injection of Viral Vectors Maria Pereira1, Marcella Birtele1, Daniella Rylander Ottosson1 1Department of Experimental Medi
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/jove_0.pdf - 2026-10-02
56TH ANNUAL MEETING OF THE EUROPEAN ASSOCIATION FOR THE STUDY OF DIABETES Content Page EASD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Morgagni Prize . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
https://www.ludc.lu.se/sites/ludc.lu.se/files/easd2020_finalprogramme.pdf - 2026-10-02
© The Author(s) 2021. Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. 1 Distinct subcellular aut
© 2022. Published by The Company of Biologists Ltd. Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain Marcella Birtele 1 , Petter Storm 1 , Yogita Sharma 1 , Janko Kajtez 1 , Jenny Nelander Wahlestedt 1 , Edoardo Sozzi 1 , Fredrik Nilsson 1 , Simon Stott 3 , Xiaoling L He 3 , Bengt Mattsson 1 , Daniella Rylander
doi:10.1016/j.expneurol.2006.04.022 Retrovirally delivered Islet-1 increases recruitment of Ng2 expressing cells from the postnatal SVZ into the striatum Nina Rogelius a,⁎, Josephine B. Jensen a,b, Cecilia Lundberg a, Malin Parmar a,b,⁎ a Wallenberg Neuroscience Center, Department of Experimental Medical Science, Lund University, BMC A11, SE-221 84 Lund, Sweden b Lund Strategic Center for Stem Cel
doi:10.1016/S1044-7431(03)00097-6 A transplantation study of expanded human embryonic forebrain precursors: evidence for selection of a specific progenitor population Malin Parmar,* Charlotta Skogh, and Ulrica Englund1 Wallenberg Neuroscience Center, BMC A11, Section of Neurobiology, Lund University, SE-221 84 Lund, Sweden Received 2 January 2003; revised 12 March 2003; accepted 17 March 2003 Abst
Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids ARTICLE Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids Alessandro Fiorenzano 1✉, Edoardo Sozzi 1, Marcella Birtele 1, Janko Kajtez 1, Jessica Giacomoni 1, Fredrik Nilsson 1, Andreas Bruzelius 2, Yo
In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain–striatum–cortex assembloids Nature Methods nature methods https://doi.org/10.1038/s41592-023-02080-xArticle In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain–striatum–cortex assembloids Ventral midbrain dopaminergic neurons project to the striatum as well as the c
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease ARTICLE Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease Katarína Tiklová1,2,6, Sara Nolbrant 3,6, Alessandro Fiorenzano3,6, Åsa K. Björklund 4, Yogita Sharma3, Andreas Heuer 3, Linda Gillberg1,2, Deirdre B. Hoban3, Tiago Cardoso
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_nature_com.pdf - 2026-10-02
Cardoso_et_al-2018-Journal_of_Comparative_Neurology(1).pdf R E S E A R CH AR T I C L E Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats Tiago Cardoso1,2 | Andrew F. Adler1,2 | Bengt Mattsson1,2 | Deirdre B. Hoban1,2 | Sara Nolbrant1,2 | Jenny Nelander Wahlestedt1,2 | Agnete Kirkeby1,3 | Shane Grealis
