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Aim: Several studies have addressed the association between changes in the female sex hormones estrogen and progesterone levels and changes in parameters of periodontitis. In order to understand how these hormones affect periodontal health it is of major importance to obtain information on their physiological importance. We have previously shown that periodontal ligament cells (PDL cells) express
The node of Ranvier is the key element in saltatory conduction along myelinated axons, but its specific protein organization remains elusive in the human species. To shed light on nanoscale anatomy of the human node of Ranvier in health and disease, we assessed human nerve biopsies of patients with polyneuropathy by super-resolution fluorescence microscopy. We applied direct stochastic optical rec
Formerly known as the Live Cell Imaging platform Live imaging is an important tool for studying the molecular and cellular functions of neuronal and non-neuronal cells and tissue. It has a broad range of applications, such as exploring disease mechanisms, assisting with clinical diagnosis and development of new treatments. This system gives MultiPark scientists an opportunity to study single molec
https://www.multipark.lu.se/infrastructures/microscopy-and-imaging-software/nikon-eclipse-ti-live-imaging-system - 2026-10-01
Introduktion: Flera studier har påpekat att det kan finnas ett samband mellan förändringar i nivån av kvinnligt könshormon och förvärrad tandlossning. Hur östrogen påverkar tandfästet är inte kartlagt. Det finns två östrogenreceptorer (ER), ERα och ERβ och betydelsen av de båda receptorerna är inte kartlagda. Målet med denna avhandling har varit att undersöka uttrycket av ER i bindvävsceller i rotAbstract INTRODUCTION: Several studies have addressed the association between changes in levels of the female sex hormone, estrogen, and changes in the parameters of periodontitis, but the mechanism behind estrogenic effects in the periodontium is poorly understood. There are two subtypes of estrogen receptors (ER), ERalpha and ERbeta. The objectives of the present studies were to map periodontal
250224 Name of PI Malin Parmar Faculty/Department Faculty of medicine/Experimental medical science (EMV) E-mail malin.parmar@med.lu.se Telephone +46 46 222 06 20 Cost center 314062 Responsible researcher Edoardo Sozzi E-mail to researcher edoardo.sozzi@med.lu.se Project title Fabrication of microfluidic devices for connectoid formation Aim of project (max 1100 characters) The aim of this first exp
https://www.bme.lth.se/sites/bme.lth.se/files/2025-10/12_MalinParmar_250224.pdf - 2026-10-03
https://www.admire.lu.se/links/ - 2026-10-01
Cell-type-specific neuronal activation the sensorimotor cortex in L-DOPA-induced dyskinesia Markus Aldén1, Osama Elabi1, Martina Harley Leanza1, M. Angela Cenci1 1. Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, Lund, Sweden L-DOPA-induced dyskinesia (LID) is a common complication of Parkinson´s disease pharmacotherapy. Knowledge about the involvem
https://www.neuroscience.lu.se/sites/neuroscience.lu.se/files/2026-05/all_abstracts.pdf - 2026-10-03
Due to their unique optical properties, III-V nanowires are promising candidates for the development of efficient solar cells, LEDs and nanoscaled lasers. The interaction of nanowires with fluorescent molecules is also of interest, as these nanostructures can act as nanoscaled optical fibers. The light emitted by a fluorophore close to a nanowire surface can in fact couple into the supported waveg
Popular Abstract in English 111-Indium is a radioactive isotope that can be chemically linked to different molecules. When this compound is given to patients is distributed heterogeneously within the structures that build up the testicle. Different parts of the so-called germ cells are sensitive to radiation in different ways. Therefore, if a radioisotope that send out electrons with low energies It is well known that the testicles are among the most radiosensitive tissue, and constitute an important critical target for both external and internal radiation during diagnostic and therapeutic use of radionuclides. In systemic radionuclide therapy where very high activities are administered, the testis may become a dose-limiting organ; often with a complex, non-uniform activity distribution an
Nanowires hold great promise as tools for probing and interacting with various molecular and biological systems. Their unique geometrical properties (typically <100 nm in diameter and a few micrometers in length) enable minimally invasive interactions with living cells, so that electrical signals or forces can be monitored. All such experiments require in situ high-resolution imaging to provide co
MultiPark infrastructure survey MultiPark infrastructure survey May 2018 Overview • Sent out to 48 senior researchers, 33 responded (68,75%) • Included 26 platforms/infrastructures (one platform missed, one under startup) • Analysis scoring » Disagree= 1 point » Slightly Disagree= 2 points » Neutral= 3 points » Slightly Agree= 4 points » Agree= 5 points » N.A./don’t know: not included in the calcu
https://www.multipark.lu.se/sites/multipark.lu.se/files/summary_revised_infrastructure_report.pdf - 2026-10-03
Budget follow-up 2019_excel Budget 2019 UTFALL 2019.12.31 INKL OH Diff vs budget General Budget MultiPark EMV OH 23,5% Income 28 842 000 28 842 000 0 Balance from previous year (estimated) 10 975 226 10 273 062 702 164 Rent subvention 246 202 253 330 7 128 Income Total 40 063 428 39 368 392 -695 036 40 063 428 Management Coordinators (2 persons 50%) 951 755 951 865 -110 Admin personnel (1 person,
https://www.multipark.lu.se/sites/multipark.lu.se/files/2021-09/Budget%20follow-up%202019.pdf - 2026-10-03
Nanoscience_Colloquium_2018_01_21_Ed_Boyden_lores For full program of NanoScience Colloquia see: http://www.nano.lu.se/news-and-events/nanoscience-colloquia NNAANNOOSSCCIIEENNCCEE CCOOLLLLOOQQUUIIUUMM Prof. Edward S. Boyden Monday January 21st, 2019 at 15:15, in Rydbergssalen, Fysicum Nanotechnology for Mapping, Controlling, and Building Brain Circuits and Other Complex Systems Y. Eva Tan Professo
https://www.nano.lu.se/sites/nano.lu.se/files/nanoscience_colloquium_2018_01_21_ed_boyden_lores.pdf - 2026-10-03
PRELP is a heparin-binding leucine-rich repeat protein in connective tissue extracellular matrix. In search of natural ligands and biological functions of this molecule, we found that PRELP binds the basement membrane heparan sulfate proteoglycan perlecan. Also recombinant perlecan domains I and V carrying heparan sulfate bound PRELP, whereas other domains without glycosaminoglycan substitution di
A better understanding of skeletal muscle lipid metabolism is needed to identify the molecular mechanisms relating intramuscular triglyceride (IMTG) to muscle metabolism and insulin sensitivity. An increasing number of proteins have been reported to be associated with intracellular triglyceride (TG), among them the PAT family members: perilipin, ADRP ( for adipocyte differentiation-related protein
Preclinical trials of cancer drugs in animal models are important for drug development. The Rip1Tag2 (RT2) transgenic mouse, a model of pancreatic neuroendocrine tumours (PNET), has provided immense knowledge about PNET biology, although tumour progression occurs in a location inaccessible for real-time monitoring. To overcome this hurdle we have developed a novel platform for intravital 3D imagin
Budget 2021 BUDGET MULTIPARK EMV OH 24% Income 29 901 000 Rent subvention 687 700 Balance from previous year (estimated) 1 450 000 Income total 32 038 700 A - Management Coordinator salary "intrångsersättning" (35%) 625 619 Vice-oordinators salary "intrångsersättning" (15%) 383 653 Research administrator salary (100%) 806 623 Remuneration board members 60 000 Management (meetings, computer, travel
https://www.multipark.lu.se/sites/multipark.lu.se/files/2020-12-15.pdf - 2026-10-03
