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Ficolins are soluble molecules that bind carbohydrate present on the surface of microorganisms and function as recognition molecules in the lectin complement pathway. Three ficolins have been identified in humans: ficolin-1, ficolin-2, and ficolin-3. Ficolin-1 is synthesized in monocytes and type II alveolar epithelial cells. Ficolin-1 has been shown to be present in secretory granules of human ne
Coxsackievirus A24 variant (CVA24v) is a major causative agent of acute hemorrhagic conjunctivitis outbreaks worldwide, yet the evolutionary and transmission dynamics of the virus remain unclear. To address this, we analyzed and compared the 3C and partial VP1 gene regions of CVA24v isolates obtained from five outbreaks in Cuba between 1986 and 2009 and strains isolated worldwide. Here we show tha
This study conducted a comprehensive evaluation of three satellite precipitation products (TRMM (Tropical Rainfall Measuring Mission) 3B42, CMORPH (the Climate Prediction Center (CPC) Morphing algorithm), and PERSIANN (Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks)) using data from 52 rain gauge stations over the Meichuan watershed, which is a represent
Solar variability has been hypothesized to be a major driver of North Atlantic millennial-scale climate variations through the Holocene along with orbitally induced insolation change. However, another important climate driver, volcanic forcing has generally been underestimated prior to the past 2,500 years partly owing to the lack of proper proxy temperature records. Here, we reconstruct seasonall
The Arctic is a popular place to do research. Many countries fund scientific research projects in the region, and international scientists are a considerable part of the Arctic population. Knowledge and expertise about the Arctic is no longer restricted to the Arctic states. Less controversial than flag planting at the North Pole and test drilling for oil, scientists and research stations are ofte
This paper is dedicated to a global correlation of marine Permian-Triassic boundary layers on the basis of partially published and original data on the δ13Corg and δ13Ccarb values of the Suol section (Setorym River, South Verkhoyansk region). The section consists of six carbon isotopic intervals, which are easily distinguishable in the carbon isotopic curves for a series of Permian-Triassic refere
Translational regulation of ornithine decarboxylase (ODC), which catalyses the first step in the biosynthesis of polyamines, appears to be an important mechanism in the strong feedback control as well as in the hypotonic induction of the enzyme. However, the exact mechanisms are not yet understood. The ODC mRNA has long 5' and 3' untranslated regions (UTRs) which may be involved in the translation
To keep global warming within 1.5 °C of pre-industrial levels, there needs to be a substantial decline in the use of coal power by 20301,2 and in most scenarios, complete cessation by 2050. The members of the Powering Past Coal Alliance (PPCA), launched in 2017 at the UNFCCC Conference of the Parties, are committed to “phasing out existing unabated coal power generation and a moratorium on new coa
I sverige använder man främst geologisk kartering, geofysik och borrning som prospekteringsmetoder, men forskning och internationella fallstudier visar att grundvattnet är en outnyttjad informationskälla som kan göra letandet efter malm både träffsäkrare och mer hållbart. När mineraliseringar vittrar läcker exempelvis metaller som koppar, zink eller litium ut i grundvattnet och sprids med flödet. In Sweden, geological mapping, geophysics, and drilling are primarily used as exploration methods, but research and international case studies show that groundwater is an untapped source of information that can make the search for ore both more accurate and more sustainable. As mineralisations weather, metals such as copper, zinc, or lithium leach into the groundwater and are transported with the
Internal social media (ISM) platforms have transformed internal communication by enabling dialogue, participation, and shared meaning-making across organizational hierarchies and locations. While previous research has highlighted ISM’s role in knowledge sharing and employee engagement, less attention has been paid to its function in shaping organizational identity from a managerial perspective. Th
