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One hypothesis for the reduction of vision in cave animals, such as the eyeless Mexican cavefish, is the high energetic cost of neural tissue and low food availability in subterranean habitats. However, data on relative brain and eye mass in this species or on any measure of the energetic cost of neural tissue are not available, making it difficult to evaluate the "expensive tissue hypothesis." We
Cost-benefit-analyses (CBA) are widely used to assess transport projects. Comparing various CBA frameworks, this paper concludes that the range of parameters considered in EU transport CBA is limited. A comprehensive list of criteria is presented, and unit costs identified. These are used to calculate the external and private cost of automobility, cycling and walking in the European Union. Results
Title: A framework for understanding the cost of servicing customers when orders are at risk of late delivery – A case study at Tetra Pak Authors: Simon Lundqvist and Alexander Olsson Supervisors: Eva Berg, Division of Industrial Management and Logistics, Lund University Michael Hultberg, Global supply planning manager, Tetra Pak Examiner: Jan Olhager, Division of Industrial Management and Logisti
Multi-functionality and the provision of eco-system services are politically highly prioritised aspects of farming. This study uses a Symmetric Generalised McFadden cost function to analyze the relationship between costs of production and the provision of biodiversity for Swedish milk farms. Biodiversity indicators are based on the number of valuable plant species present at the farm and are model
Inbreeding depression is assumed to be a central factor contributing to the stability of plant mating systems. Predicting the fitness consequence of inbreeding in natural populations is complicated, however, because it may be affected by the mating histories of populations generating variation in the amount of purging of deleterious alleles. Furthermore, the level of inbreeding depression may depe
Even as the public awareness and concern about climate change are increasing, and the younger generations are urging for political action, support for more costly and ambitious mitigation policies is not given. The low-cost hypothesis theory provides an explanation for why our concern about climate change fails to translate into supporting policies when the personal cost is high. However, research
The international prognostic index (IPI) and similar models form the cornerstone of clinical assessment in newly diagnosed diffuse large B-cell lymphoma (DLBCL). While being simple and convenient to use, their inadequate use of the available clinical data is a major weakness. In this study, we compared performance of the International Prognostic Index (IPI) and its variations (R-IPI and NCCN-IPI)
Electric Road Systems (ERS) have emerged as an alternative to deal with the main drawbacks that battery electric vehicles present (i.e., higher cost, short driving range, long charging times, etc.). This paper analyses the societal cost of electrifying all road transport in Denmark under four different scenarios. The first scenario considered in this study is based on today's approach of having el
This paper examines whether Sweden's shift towards New Public Management (NPM) has affected unemployment and crime rates at the municipal level. Using panel data from 290 Swedish municipalities (1995–2021) and a regression discontinuity design, I test whether left-wing governance (as a proxy for lower NPM adoption) impacts these social outcomes. Results show that narrower left-wing coalition g
ObjectiveTo evaluate the long-term costs and quality of life (QoL) with and without disease-modifying treatments (DMTs) of patients with multiple sclerosis (MS).MethodsData on resource consumption, productivity losses, QoL (utility), and fatigue were collected from 1355 patients registered with a patient association and descriptive analyses was performed.A Markov model was developed to estimate co
Thermodynamics connects our knowledge of the world to our capability to manipulate and thus to control it. This crucial role of control is exemplified by the third law of thermodynamics, Nernst's unattainability principle, which states that infinite resources are required to cool a system to absolute zero temperature. But what are these resources and how should they be utilized And how does this r
Background: There is an intense debate about the cost of cancer and the value of new treatments. However, there is limited data on the cost of cancer in the European Union (EU) and how costs relate to the burden of disease. This paper presents new estimates on the development of the cost of cancer in the EU 1995–2014, with a focus on the major cost components: total health expenditure, cancer drug
Background and Objective: Epilepsy is one of the most common neurological disorders, affecting more than 3 million people in Europe. This paper reviews the published evidence regarding the cost effectiveness of second-generation antiepileptic drugs (AEDs). Methods: A systematic literature search was performed, using the databases Academic Search Complete, Econlit, EMBASE and MEDLINE. Health econom
