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OBJECTIVES: Esophageal cancer is a highly fatal malignant neoplasm, with 2 etiologically different histological types. A large prospective study is expected to elucidate the specific risk of the 90% subtype of esophageal cancer, esophageal squamous cell carcinoma (ESCC), with metformin therapy. This study aims to determine the association between metformin use and incident ESCC risk.METHODS: This
INTRODUCTION: Esophageal squamous cell carcinoma (ESCC) carries a poor prognosis, but earlier tumor detection would improve survival. We aimed to develop and externally validate a risk prediction model based on exposure to readily available risk factors to identify high-risk individuals of ESCC.METHODS: Competing risk regression modeling was used to develop a risk prediction model. Individuals' ab
Introduction: The CVA24 antigenic variant is the causal agent of epidemics of acute hemorrhagic conjunctivitis that has prevailed to date. To study the transmission dynamics and evolution of this variant, we molecularly characterized Cuban isolates obtained in 5 epidemic periods between 1986 and 2009. Methods: Using the BEAST v1.8.4 program, it was performed the phylogenetic and phylodynamic analy
Background: Timely and safe elective health care facilitates return to normal activities for patients and prevents emergency admissions. Surgery is a cornerstone of elective care and relies on complex pathways. This study aimed to take a whole-system approach to evaluating access to and quality of elective health care globally, using inguinal hernia as a tracer condition. Methods: This was a prosp
1 VERKSAMHETSPLAN FÖR MEDICINSKA FAKULTETEN 2024 Diarienr STYR 2023/2082 2 3 1 Inledning ................................................................................................................................... 5 2 Universitetets och fakultetens omvärld ..................................................................................... 6 2.1 Budgetpropositionen för 2024 ...............
STUDY PROTOCOL 2010-11-08 Study protocol: EpiHealth Version 1 CLINICAL STUDY PROTOCOL EpiHealth (Epidemiology for Health) – A multicenter longitudinal cohort study A Lund-Uppsala University collaborative project 1 2010-11-08 Study protocol: EpiHealth Version 1 UCR Project No: U-10-012 Sponsor: Uppsala University Sponsor Representative: Professor Lars Lind, MD, PhD Department of Medical Sciences, U
https://www.epihealth.lu.se/sites/epihealth.lu.se/files/epihealth_studieprotokoll_101103.pdf - 2026-06-24
Background: In a previous study, we explored real-world programmed death-ligand 1 (PD-L1) testing and treatment patterns for patients with advanced non-small cell lung cancer (NSCLC) in the era of immune-oncology. The present study aimed to investigate overall survival (OS) with PD-(L)1 inhibitors with longer-term follow-up in the Swedish setting. Materials and methods: Data were extracted from th
BACKGROUND: There is limited data regarding SARS-CoV-2 vaccine uptake in people with HIV (PWH) compared to people without HIV (PWoH).METHODS: Swedish nationwide study of individuals born 1930-2003, assessing SARS-CoV-2 vaccine uptake of 1-5 doses by HIV-status from first SARS-CoV-2 vaccination (2020-12-27) until 2023-02-23. PWH were categorized by prioritization: clinically vulnerable (CD4+ T-cell
Introduction: Alcohol use has significant health implications, yet the association between alcohol use and respiratory symptoms remains relatively understudied. This study examines the prevalence of hazardous alcohol use and its associations with breathlessness, chronic cough, and health-related quality of life (HRQoL) and whether these associations with chronic airway limitation (CAL) differ by a
Many cities in the Global South are facing challenges as they increasingly experience extreme weather events, which disproportionately affect the urban poor. Focussing on severe heat and surface water flooding, this paper explores how these extreme weather events impact on infrastructure provision and livelihoods in low-income urban communities in Ghana. Climate series, including temperature data
Gourse analysis GEON09 Global Environmental Change from a Geological Perspective Spring term 2022 General: The course was taught for the first time during the spring term of 2022. Therefore, this course analysis is especially important for our further development of the course. Twelve students completed the course, of which eight responded to the course evaluation (appended below). The course, whi
https://www.geology.lu.se/sites/geology.lu.se/files/2022-10/Coure%20analysis%20GEON09%202022.pdf - 2026-06-24
LIFEGENE EpiHealth Ethics Policy, Version 1, 2010-11-09 Page 1 of 18 EpiHealth Ethics Policy Version 1, November 9, 2010 2 Table of Contents Table of Contents ............................................................................................... 2 EpiHealth - Purpose and overview ..................................................................... 4 I. Relationship with participants ....
https://www.epihealth.lu.se/sites/epihealth.lu.se/files/epihealth_ethics_policy_101108_0.pdf - 2026-06-24
Utbildningsplan Naturvetenskapligt kandidatprogram Naturvetenskapliga fakulteten NGNAT, Naturvetenskapligt kandidatprogram, 180 högskolepoäng Sciences, 180 credits Program utan akademiska förkunskapskrav och med slutlig examen på grundnivå / First cycle degree programme not requiring previous university study Beslutsuppgifter Utbildningsplanen är fastställd av Naturvetenskapliga fakultetsstyrelsen
https://www.geologi.lu.se/sites/geologi.lu.se/files/2021-11/NGNAT.pdf - 2026-06-24
Evaluation GEOM10-2021 Answer Count: 9 Please grade the statements below from 1-5: Disagree (1) – Agree (5) Overall, I was satisfied with the quality of this course. Overall, I was satisfied with the quality of this course. Number of res- ponses 1 0 (0.0%) 2 0 (0.0%) 3 0 (0.0%) 4 4 (44.4%) 5 5 (55.6%) Total 9 (100.0%) Mean Standard Deviation Overall, I was satisfied with the quality of this course
https://www.geology.lu.se/sites/geology.lu.se/files/2022-03/GEOM10%20Course%20evaluation%202021.pdf - 2026-06-24
Lineage tracing of stem cell–derived dopamine grafts in a Parkinson’s model reveals shared origin of all graft-derived cells Storm et al., Sci. Adv. 10, eadn3057 (2024) 18 October 2024 S c i e n c e A d v A n c e S | R e S e A R c h A R t i c l e 1 of 14 N E U R O S C I E N C E Lineage tracing of stem cell–derived dopamine grafts in a Parkinson’s model reveals shared origin of all graft- derived c
This work consists of seven essays, with each concerning a specific subject that is related to architecture. There is additional text, which pertains to this work's examination requirements for graduating the architecture-program at Lund Technical University. This work is a creative explorations through writing as a tool; through text; becoming able to formulate, conceptualize, develop and ext
Background: We set out to profile the immune mechanisms active in treatment-naïve oligoarticular JIA (oJIA) to improve the knowledge of its immunopathogenesis, to identify potential biomarkers that can aid diagnosis, predictions and that correlate with clinical disease parameters. Methods: Using Olink proteomics (inflammation panel measuring 92 markers), we defined and compared the inflammation pr
In Nordic countries, demand response (DR) programs are critical for enhancing energy flexibility and reducing peak electricity consumption in buildings and industry. Accurate short-term demand forecasting is essential to support these programs, especially in the context of cities with varying levels of data availability. This paper compares three different forecasting approaches for hourly electri
Background In several countries, whole-body imaging has been introduced in the routine follow-up of individuals with high-risk cutaneous malignant melanoma after surgery. However, there is scarce evidence that earlier detection of recurrent disease by regular scanning improves survival. In this interim analysis, we investigated whether imaging in the follow-up programme for high-risk cutaneous mal
RATIONALE: Acute otitis media (AOM) is one of the most common bacterial infections in children worldwide, and the most common reason for prescribing antibiotics. Although serious complications (e.g. mastoiditis or meningitis) are rare, the infection causes acute pain and can lead to hearing impairment. Since AOM often resolves spontaneously, current treatment guidelines recommend an approach of wa
