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Several quantitative trait loci regulating murine Lyme arthritis severity have been mapped, including a highly significant linkage found on chromosome 5, termed Bb2Bb3. Within this region, the Ncf1 gene of the phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase has recently been identified as a major regulator of arthritis severity in rodent models of rheumatoid arthritis, an eff
The ternary Zintl phase Ca3Ag1+xGe3x (x = 1/3) was synthesized by the high-temperature solid-state technique and its crystal structure was refined from single-crystal diffraction data. The compound Ca3Ag1.32Ge2.68(1) adopts the Sc3NiSi3 type structure, crystal data: space group C2/m, a = 10.813(1) angstrom, b = 4.5346(4) angstrom, c = 14.3391(7) angstrom, beta = 110.05(1)degrees and V = 660.48(10)
BACKGROUND:: The differentiation between a giant fibroadenoma and a phyllodes tumor can be a precarious diagnostic task. However, the distinction between the 2 lesions is important to make, especially since the latter can be malignant and consequently the prognoses differ. PROCEDURE:: We used various genetic approaches to study a breast tumor showing features of both entities in a 10-year-old girl
Progression to hormone-refractory growth of prostate cancer has been suggested to be mediated by androgen receptor (AR) gene alterations. We analyzed AR for mutations and amplifications in 21 locally recurrent prostate carcinomas treated with orchiectomy, estrogens, or a combination of orchiectomy and estramustine phosphate using fluorescence in situ hybridization, single-strand conformation polym
A remote sensing system for combined fluorescence spectral recordings and multi-colour fluorescence imaging of vegetation will be presented. The system configuration will be explained and data from several field campaigns will be shown. The excitation light pulses for remote fluorescence detection are produced by a frequency tripled Nd:YAG laser emitting at 355 nm and shifted to 397 nm in a deuter
The purpose of this study was testing and performance simulation of an innovative tracking hybrid solar system being developed by the Swedish Company Arontis. The Solar8 collector produces both electrical and thermal energy in one system. Its performance was compared with conventional photovoltaic panels and solar thermal collectors working side-by-side which are already on the market. The solar8
For treatment of systemic malignancies, when external radiation therapy is not applicable, radionuclide therapy can be an alternative. In this form of therapy, radionuclides are administered to the patient, often in a form where the radionuclide is labelled to a molecule that plays the active part in the localization of the tumor. Since the aim is to impart lethal damage to tumor cells while maint
The p16 (CDKN2/MTS1/INK4a) malignant melanoma susceptibility gene was analyzed in 10 melanoma kindreds from southern Sweden using single-stranded conformation polymorphism analysis of all three exons and flanking intron regions followed by sequence analysis. A novel germline mutation, constituting an in-frame 3-bp duplication at nucleotide 332 in exon 2, was identified in two families (Lund M2 and
Mint/X11 is one of the four neuronal trafficking adaptors that interact with amyloid precursor protein (APP) and are linked with its cleavage to generate β-amyloid peptide, a key player in the pathology of Alzheimer's disease. How APP switches between adaptors at different stages of the secretory pathway is poorly understood. Here, we show that tyrosine phosphorylation of Mint1 regulates the desti
Halide perovskites are emerging as revolutionary materials for optoelectronics. Their ionic nature and the presence of mobile ionic defects within the crystal structure have a dramatic influence on the operation of thin-film devices such as solar cells, light-emitting diodes, and transistors. Thin films are often polycrystalline and it is still under debate how grain boundaries affect the migratio
A wind-borne plume of sex pheromone from a female moth or a synthetic source has a fine, filamentous structure that creates steep and rapid fluctuations in concentration from a male moth flying up the plume's axis. The firing rates from single antennal neurons on Agrotis segetum antennae decreased to nearly zero within seconds after the antennae were placed in a pheromone plume 70 cm downwind of a
The first measured results for massive multiple input, multiple-output (MIMO) performance in a line-of-sight (LOS) scenario with moderate mobility are presented, with 8 users served in real-time using a 100 antenna base Station (BS) at 3.7 GHz. When such a large number of channels dynamically change, the inherent propagation and processing delay has a critical relationship with the rate of change,
Uropathogenic Escherichia coli elicit a host response that determines the severity of urinary tract infection (UTI). Specific adherence mechanisms allow the bacteria to initiate this process by targeting epithelial cells in the urinary tract mucosa. Epidemiological studies show a strong association of P-fimbriae with disease severity, suggesting that adherence mediated by these organelles has a di
Flowers and fruits of Zlivifructus microtriasseris, originally described as Caryanthus microtriasseris from the late Turonian to Santonian of the South Bohemian Basins and the late Coniacian to early Santonian of the North Sudetic Basin, are reinterpreted here. Zlivifructus microtriasseris is represented by small, flat fruits, round in outline with persistent perianths, which are fused basally, fo
A cellular automaton algorithm with probabilistic cell switches is employed in the simulation of dynamic discontinuous recrystallization. Recrystallization kinetics are formulated on a microlevel where, once nucleated, new grains grow under the driving pressure available from the competing processes of stored energy minimization and boundary energy reduction. Simulations of the microstructural cha
Time to AIDS infection is longer with HIV-2, compared to HIV-1, but without antiretroviral therapy both infections will cause AIDS-related mortality. In HIV-2 infection, monitoring of antiretroviral treatment (ART) efficacy is challenging since a large proportion of HIV-2-infected individuals displays low or undetectable plasma RNA levels. Hence, quantification of cellular DNA load may constitute
The alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (ppGpp), collectively referred to as (p)ppGpp, are key regulators of bacterial growth, stress adaptation, antibiotic tolerance and pathogenicity. We have recently shown that the Small Alarmone Synthetase (SAS) RelQ from the Gram-positive pathogen Enterococcus faecalis has an RNA-binding activity (Beljantseva et al. 2017)
Phytantriol Q224 cubic phase, as a bicontinuous meso-structured material stable in contact with aqueous electrolyte, has found applications in drug delivery and cosmetics and is employed here as a free-standing film separating two aqueous compartments in order to study i) ion conductivity (at low potential bias within ±0.8 V), ii) conductivity switching effects (at high potential bias beyond ±0.8
Professor Contact details Email: martin [dot] berggren [at] mgeo [dot] lu [dot] seOrganisation Department of Earth and Environmental Sciences (MGeo) Service point: 16 WebpageMartin Berggrens profile in Lund University research portalOther affiliations Director of third cycle studies Department of Earth and Environmental Sciences (MGeo) Member of Strategic Research Area BECC: Biodiversity and Ecosy
https://www.nateko.lu.se/martin-berggren - 2026-10-05
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