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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 195488 hits

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Objective: Diabetes is known to be associated with increased arterial stiffness. However, the temporal association between increased carotid-femoral pulse wave velocity (c-f PWV) and diabetes is unclear. The aim of this study is to explore the relationship between arterial stiffness, as determined by c-f PWV, and incidence of diabetes. Research Design and Methods: The study population included par

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Due to phonemic restoration, listeners can reliably perceive words when a phoneme is replaced with noise. The cost associated with this process was investigated along with the effect of lexical uniqueness on phonemic restoration, using data from a lexical decision experiment where noise replaced phonemes that were either uniqueness points (the phoneme at which a word deviates from all nonrelated w

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Populations adapting independently to the same environment provide important insights into the repeatability of evolution at different levels of biological organization. In the 20th century, common wall lizards (Podarcis muralis) from southern and western Europe were introduced to England, north of their native range. Nonnative populations of both lineages have adapted to the shorter season and lo

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Migration is energetically demanding and physiologically challenging. Migrating birds, for example, need to boost their antioxidant defenses to defeat the pro-oxidants produced during high energetic activity. The enhanced antioxidant defense possibly withdraws limited resources (e.g., energy or micronutrients) from other physiological functions, such as immune defense. Such a trade-off might not o

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In 2 studies with a total of over 300 participants, the Epstein Creativity Competencies Inventory for Individuals (ECCI-i) was shown to be a reliable measuring instrument. In the first of these studies, the test was also shown to be a valid predictor of 2 measures of creative expression. The test is derived from empirical research on the creative process in individuals, which suggests that creativ

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We develop a method for patterning a buried two-dimensional electron gas (2DEG) in silicon using low kinetic energy electron stimulated desorption (LEESD) of a monohydride resist mask. A buried 2DEG forms as a result of placing a dense and narrow profile of phosphorus dopants beneath the silicon surface; a so-called δ -layer. Such 2D dopant profiles have previously been studied theoretically, and

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Hospitalised patients are faced with a brute reorientation of their normal spatial needs andpreferences and forced to adjust spatially to a new environment. Patients start to re-arrangetheir own situation according to personal needs and the site-specific circumstances. It is are-arrangement that includes furniture, private objects and spatial positioning, but also theadjustment to the presence and

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The publication of 'A darker side of hypermobility' (Cohen and Gössling, 2015), which reviewed the personal and social consequences of frequent travel, led to considerable media coverage and sparking of the public imagination, particularly with regards to the impacts of business travel. It featured in more than 85 news outlets across 17 countries, engendering over 150,000 social media shares and 4

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Following an adverse event in a Swedish university hospital in 2010, three separate investigations seeking causal factors were conducted. We here review each of the analyses to see whether they together generate the kind of epistemological pluralism that could contribute to a systemic understanding of, and learning from, the event. Our content analysis shows that, while using vastly different amou

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In this pilot study, the authors introduce a new system to assess hypnosis style. The Feature-Based Coding System (FBCS) comprises 24 standard individual hypnosis sessions, which were videotaped and coded according to both a previous and the new coding system. In addition, both subjects and hypnotists filled the Archaic Involvement Measure (AIM), the Phenomenology of Consciousness Inventory (PCI),

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The recycling, S-nitrosylated heparan sulfate (HS) proteoglycan glypican-1 releases anhydromannose (anMan)-containing HS chains by a nitrosothiol-catalyzed cleavage in endosomes that can be constitutive or induced by ascorbate. The HS-anMan chains are then transported to the nucleus. A specific nuclear target for HS-anMan has not been identified. We have monitored endosome-to-nucleus trafficking o

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Objective: To determine if blood neurofilament light chain (NfL) protein can discriminate between Parkinson disease (PD) and atypical parkinsonian disorders (APD) with equally high diagnostic accuracy as CSF NfL, and can therefore improve the diagnostic workup of parkinsonian disorders. Methods: The study included 3 independent prospective cohorts: the Lund (n = 278) and London (n = 117) cohorts,

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This review article considers the purposes and mechanisms of regulation of placental transfer in general terms and then illustrates some key points with reference to the Na+/H+ exchanger (NHE), a transport protein found in the syncytiotrophoblast. NHE probably has a role in the homeostasis of syncytiotrophoblast intracellular pH and may also be involved in syncytiotrophoblast cell volume regulatio

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Place branding is commonly understood as the general phenomenon of marketing, branding, promoting and regeneration of a particular city, region and/or location. Place branding has attracted an increasing number of researchers belonging to different disciplines producing a highly interdisciplinary literature. However, the complexity and problems connected with it has not been coped with sufficientl