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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 194805 hits

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Blood coagulation and complement pathways are two important natural defense systems. The high affinity interaction between the anticoagulant vitamin K-dependent protein S and the complement regulator C4b-binding protein (C4BP) is a direct physical link between the two systems. In human plasma, similar to 70% of total protein S circulates in complex with C4BP; the remaining is free. The anticoagula

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Aims: To explore the association between tooth loss and obesity in an adult Swedish population, and to investigate the influence of socioeconomy, life-style, and co-morbidity. Methods: A cross-sectional population health survey conducted in 2001-2005 in 2816 randomly selected Swedish men and women (age: 30-74 years; participation rate 76%). Main measures were; tooth loss: < 20 remaining teeth (sel

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The ability to invent means to deceive others, where the deception lies in the perceptually or contextually detached future, appears to require the coordination of sophisticated cognitive skills toward a single goal. Meanwhile innovation for a current situation has been observed in a wide range of species. Planning, on the one hand, and the social cognition required for deception on the other, hav

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Context Software startups are newly created companies with no operating history and fast in producing cutting-edge technologies. These companies develop software under highly uncertain conditions, tackling fast-growing markets under severe lack of resources. Therefore, software startups present a unique combination of characteristics which pose several challenges to software development activitie

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We present the radial velocity curve of a single-lined spectroscopic binary in the faint Hercules dwarf spheroidal (dSph) galaxy, based on 34 individual spectra covering more than 2 yr of observations. This is the first time that orbital elements could be derived for a binary in a dSph. The system consists of a metal-poor red giant and a low-mass companion, possibly a white dwarf, with a 135 day p

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Background: In recent years, research on the association between physical environments and cardiovascular disease outcomes has gained momentum with growing attention being paid to Geographic Information Systems (GIS). This nationwide study is the first to examine the effect of neighbourhood physical environments on individual-level stroke, using GIS-based measures of neighbourhood availability of

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Model-Based Design is a development method that is becoming popular to use when creating control systems. In this thesis a demonstration of the advantages of using this method is made for Combine Control Systems AB. The 3D simulation software IndustrialPhysics is used to represent a real process in form of a gantry crane. A controller for this crane is developed in Simulink and Model-in-the-Loop (

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Green innovations are becoming more apparent in today’s business world, and therefore this thesis aims to contribute to the understanding of green product innovation. Particularly in the startup phase of a company, many challenges exist, and the strategic planning process is an important tool in assessing the market and in developing a superior strategy to go against competitors. To understand how

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This paper investigates if inflation dynamics in Sweden can be properly modelled by the New Keynesian Phillips Curve (NKPC). Four versions of the NKPC are tested on quarterly data between 1995 and 2016 using Generalized Method of Moments (GMM) as the estimation method. The following versions are empirically tested: the NKPC with output gap, the NKPC with marginal costs, the hybrid NKPC and the sec

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Lots of old properties in Italy are in need of getting a restoration, renovation or modernization. Most of these buildings have been abandoned many years ago, and people are now trying to raise awareness about the situation in Italy. The general Italian attitude towards old buildings has in many years been of almost total neglect. Due to this, lots of historical and old buildings are in danger of

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This master thesis explores how implementing UX design on a product with predetermined technology affects the design process and the methods applied. A UI for the display version of an Axis Door Station is designed from a human-centered design perspective. The development process is based on prototyping and usability studies focusing on the user experience. The thesis discusses if it is possible

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The intensification of forest management over the recent decades, in combination with the effects of a warming climate, leaves forestry and forest management with the challenging task of maintaining forest ecosystems’ further abilities to provide ecosystem services. By systematically reviewing peer- reviewed academic literature this study analyzes the concept of multifunctionality and its applicat

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The project was performed for FAS Converting Machinery AB (FAS) in Ystad with supervision from Industriell Elektroteknik och Automation at LTH. FAS is a company that makes machines for producing plastic bags on a roll. The problem given was to develop a sensor for detecting the perforations in the bags to ensure that the correct amount of bags was rolled up and that the tearing was in the right pl

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The present article is a functional analysis of intonation in Russian declarative utterances. Pragmatically relevant tonal patterns and their functions are identified and described. Utterances are analysed in terms of theme and rheme. Theme is signalled by a tonal rise and rheme by a falling tonal gesture. Beside thematic and rhematic tonal gestures, other rising accents in the utterance are ident

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Reaction of the tricobalt carbyne cluster [Co-3(mu(3)-CH)(CO)(9)] with chiral diphosphines of the Josiphos and Walphos families affords the new clusters [Co-3(mu(3)-CH)(CO)(7)(P-P*)] in good yield (P-P* = J004 (1), J005 (2), J007 (3), W001 (4), W003 (5)). The new alkylidyne tricobalt clusters, and the previously known [Co-3(mu(3)-CH)(CO)(7)(mu-J003)], have been tested as catalysts/catalyst precurs

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Introducing a new cat to a home with resident cats may lead to stress, aggression and even fights. In this case study 468 agonistic cat vocalisations were recorded as one cat was introduced to three resident cats in her new home. Six vocalisation types were identified: growl, howl, howl-growl, hiss, spit and snarl. Numerous other intermediate and complex vocalisations were also observed. An acoust

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A nonionic lamellar phase was prepared using C10E3 in buffer solution at pH = 7.6. A suitable T4DNA concentration around 5 wt % was immobilized in a lamellar phase with 40 wt % C10E3. The mixed system was investigated at two temperatures, 25 and 5 degrees C by using cryo-fracture TEM direct imaging, fluorescence microscopy and small-angle X-ray scattering. The surprising results where obtained sho